An Empirical Assessment of IAS 40 Investment Property

This study examines the value relevance of the fair value model versus the cost model for evaluating investment properties under IAS 40 Investment Property. Contrary to the popular belief that fair value is the most relevant measurement attribute, we find that the coefficient estimate of investment properties for Chinese companies that adopted IAS 40’s fair value model is significantly smaller than its theoretical value, and is not significantly different from zero, suggesting that reported fair values are not value relevant as perceived by investors for the sample firms. Furthermore, investors tend to adjust the valuation of fair value companies’ non-investment property assets downward. The findings do not support the claim that fair value is superior to historical cost for the investment property valuation. Our findings highlight the need for more implementation guidelines from the IASB to enhance the value relevance of fair value estimates under IAS 40

Quantum error pre-compensation for quantum noisy channels

Most previous efforts of quantum error correction focused on either extending classical error correction schemes to the quantum regime by performing a perfect correction on a subset of errors, or seeking a recovery operation to maximize the fidelity between a input state and its corresponding output state of a noisy channel. There are few results concerning quantum error pre-compensation. Here we design an error pre-compensated input state for an arbitrary quantum noisy channel and a given target output state. By following a procedure, the required input state, if it exists, can be analytically obtained in single-partite systems. Furthermore, we also present semidefinite programs to numerically obtain the error pre-compensated input states with maximal fidelities between the target state and the output state. The numerical results coincide with the analytical results.Comment: 10 pages, 3 figures

Genome-wide identification and evolution of ATP-binding cassette transporters in the ciliate Tetrahymena thermophila: A case of functional divergence in a multigene family

<p>Abstract</p> <p>Background</p> <p>In eukaryotes, ABC transporters that utilize the energy of ATP hydrolysis to expel cellular substrates into the environment are responsible for most of the efflux from cells. Many members of the superfamily of ABC transporters have been linked with resistance to multiple drugs or toxins. Owing to their medical and toxicological importance, members of the ABC superfamily have been studied in several model organisms and warrant examination in newly sequenced genomes.</p> <p>Results</p> <p>A total of 165 ABC transporter genes, constituting a highly expanded superfamily relative to its size in other eukaryotes, were identified in the macronuclear genome of the ciliate <it>Tetrahymena thermophila</it>. Based on ortholog comparisons, phylogenetic topologies and intron characterizations, each highly expanded ABC transporter family of <it>T</it>. <it>thermophila </it>was classified into several distinct groups, and hypotheses about their evolutionary relationships are presented. A comprehensive microarray analysis revealed divergent expression patterns among the members of the ABC transporter superfamily during different states of physiology and development. Many of the relatively recently formed duplicate pairs within individual ABC transporter families exhibit significantly different expression patterns. Further analysis showed that multiple mechanisms have led to functional divergence that is responsible for the preservation of duplicated genes.</p> <p>Conclusion</p> <p>Gene duplications have resulted in an extensive expansion of the superfamily of ABC transporters in the <it>Tetrahymena </it>genome, making it the largest example of its kind reported in any organism to date. Multiple independent duplications and subsequent divergence contributed to the formation of different families of ABC transporter genes. Many of the members within a gene family exhibit different expression patterns. The combination of gene duplication followed by both sequence divergence and acquisition of new patterns of expression likely plays a role in the adaptation of <it>Tetrahymen </it>a to its environment.</p

Experimental Study of the Nematic Transition in Granular Spherocylinder Packings under Tapping

Using x-ray tomography, we experimentally investigate the nematic transition in granular spherocylinder packings induced by tapping. Upon the validation of the Edwards ensemble framework in spherocylinders, we introduce an empirical free energy that accounts for the influence of gravity and the mechanical stability requirements specific to granular systems. This free energy can predict not only the correct phase transition behavior of the system from a disordered state to a nematic phase, but also a phase coexistence range and nucleation energy barriers that agree with experimental observations.Comment: 19 pages, 5 figure

Rethinking the Metric in Few-shot Learning: From an Adaptive Multi-Distance Perspective

Few-shot learning problem focuses on recognizing unseen classes given a few labeled images. In recent effort, more attention is paid to fine-grained feature embedding, ignoring the relationship among different distance metrics. In this paper, for the first time, we investigate the contributions of different distance metrics, and propose an adaptive fusion scheme, bringing significant improvements in few-shot classification. We start from a naive baseline of confidence summation and demonstrate the necessity of exploiting the complementary property of different distance metrics. By finding the competition problem among them, built upon the baseline, we propose an Adaptive Metrics Module (AMM) to decouple metrics fusion into metric-prediction fusion and metric-losses fusion. The former encourages mutual complementary, while the latter alleviates metric competition via multi-task collaborative learning. Based on AMM, we design a few-shot classification framework AMTNet, including the AMM and the Global Adaptive Loss (GAL), to jointly optimize the few-shot task and auxiliary self-supervised task, making the embedding features more robust. In the experiment, the proposed AMM achieves 2% higher performance than the naive metrics fusion module, and our AMTNet outperforms the state-of-the-arts on multiple benchmark datasets

Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies.

IntroductionQuantitative in vivo measurement of brain amyloid burden is important for both research and clinical purposes. However, the existence of multiple imaging tracers presents challenges to the interpretation of such measurements. This study presents a direct comparison of Pittsburgh compound B-based and florbetapir-based amyloid imaging in the same participants from two independent cohorts using a crossover design.MethodsPittsburgh compound B and florbetapir amyloid PET imaging data from three different cohorts were analyzed using previously established pipelines to obtain global amyloid burden measurements. These measurements were converted to the Centiloid scale to allow fair comparison between the two tracers. The mean and inter-individual variability of the two tracers were compared using multivariate linear models both cross-sectionally and longitudinally.ResultsGlobal amyloid burden measured using the two tracers were strongly correlated in both cohorts. However, higher variability was observed when florbetapir was used as the imaging tracer. The variability may be partially caused by white matter signal as partial volume correction reduces the variability and improves the correlations between the two tracers. Amyloid burden measured using both tracers was found to be in association with clinical and psychometric measurements. Longitudinal comparison of the two tracers was also performed in similar but separate cohorts whose baseline amyloid load was considered elevated (i.e., amyloid positive). No significant difference was detected in the average annualized rate of change measurements made with these two tracers.DiscussionAlthough the amyloid burden measurements were quite similar using these two tracers as expected, difference was observable even after conversion into the Centiloid scale. Further investigation is warranted to identify optimal strategies to harmonize amyloid imaging data acquired using different tracers