Investigation of the effects of the control parameters and outputs on power factor of switched reluctance motor drive systems

Author name used in this publication: X. D. XueAuthor name used in this publication: K. W. E. ChengAuthor name used in this publication: S. L. HoAuthor name used in this publication: N. C. CheungRefereed conference paper2001-2002 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

Virtual laboratory development for teaching power electronics

Author name used in this publication: Cheng K. W. E.Author name used in this publication: Cheung N. C.Author name used in this publication: Sutanto D.Power Electronics Research Centre, Department of Electrical EngineeringRefereed conference paper2001-2002 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

Chemical Printing of Biological Tissue by Gold Nanoparticle-Assisted Laser Ablation

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Investigation of voltage dip restorer using square wave inverter

Author name used in this publication: K. W. E. ChengAuthor name used in this publication: S. L. HoAuthor name used in this publication: K. P. WongRefereed conference paper2004-2005 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

Study of motoring operation of in-wheel switched reluctance motor drives for electric vehicles

Author name used in this publication: X. D. XueAuthor name used in this publication: K. W. E. ChengAuthor name used in this publication: N. C. CheungAuthor name used in this publication: Z. ZhangAuthor name used in this publication: J. K. LinRefereed conference paper2008-2009 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

LED lighting development for intelligent clothing

Author name used in this publication: K. W. E. ChengAuthor name used in this publication: Y. L. KwokAuthor name used in this publication: K. W. ChanAuthor name used in this publication: N. C. CheungAuthor name used in this publication: K. W. KwokVersion of RecordPublishe

Zebrafish cerebrospinal fluid mediates cell survival through a retinoid signaling pathway

Cerebrospinal fluid (CSF) includes conserved factors whose function is largely unexplored. To assess the role of CSF during embryonic development, CSF was repeatedly drained from embryonic zebrafish brain ventricles soon after their inflation. Removal of CSF increased cell death in the diencephalon, indicating a survival function. Factors within the CSF are required for neuroepithelial cell survival as injected mouse CSF but not artificial CSF could prevent cell death after CSF depletion. Mass spectrometry analysis of the CSF identified retinol binding protein 4 (Rbp4), which transports retinol, the precursor to retinoic acid (RA). Consistent with a role for Rbp4 in cell survival, inhibition of Rbp4 or RA synthesis increased neuroepithelial cell death. Conversely, ventricle injection of exogenous human RBP4 plus retinol, or RA alone prevented cell death after CSF depletion. Zebrafish rbp4 is highly expressed in the yolk syncytial layer, suggesting Rbp4 protein and retinol/RA precursors can be transported into the CSF from the yolk. In accord with this suggestion, injection of human RBP4 protein into the yolk prevents neuroepithelial cell death in rbp4 loss-of-function embryos. Together, these data support the model that Rbp4 and RA precursors are present within the CSF and used for synthesis of RA, which promotes embryonic neuroepithelial survival

A γA-Crystallin Mouse Mutant Secc with Small Eye, Cataract and Closed Eyelid

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Identification of “sarsasapogenin-aglyconed” timosaponins as novel Aβ-lowering modulators of amyloid precursor protein processing

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The extraordinary evolutionary history of the reticuloendotheliosis viruses

The reticuloendotheliosis viruses (REVs) comprise several closely related amphotropic retroviruses isolated from birds. These viruses exhibit several highly unusual characteristics that have not so far been adequately explained, including their extremely close relationship to mammalian retroviruses, and their presence as endogenous sequences within the genomes of certain large DNA viruses. We present evidence for an iatrogenic origin of REVs that accounts for these phenomena. Firstly, we identify endogenous retroviral fossils in mammalian genomes that share a unique recombinant structure with REVs—unequivocally demonstrating that REVs derive directly from mammalian retroviruses. Secondly, through sequencing of archived REV isolates, we confirm that contaminated Plasmodium lophurae stocks have been the source of multiple REV outbreaks in experimentally infected birds. Finally, we show that both phylogenetic and historical evidence support a scenario wherein REVs originated as mammalian retroviruses that were accidentally introduced into avian hosts in the late 1930s, during experimental studies of P. lophurae, and subsequently integrated into the fowlpox virus (FWPV) and gallid herpesvirus type 2 (GHV-2) genomes, generating recombinant DNA viruses that now circulate in wild birds and poultry. Our findings provide a novel perspective on the origin and evolution of REV, and indicate that horizontal gene transfer between virus families can expand the impact of iatrogenic transmission events