16,925 research outputs found
Computer-aided boundary delineation of agricultural lands
The National Agricultural Statistics Service of the United States Department of Agriculture (USDA) presently uses labor-intensive aerial photographic interpretation techniques to divide large geographical areas into manageable-sized units for estimating domestic crop and livestock production. Prototype software, the computer-aided stratification (CAS) system, was developed to automate the procedure, and currently runs on a Sun-based image processing system. With a background display of LANDSAT Thematic Mapper and United States Geological Survey Digital Line Graph data, the operator uses a cursor to delineate agricultural areas, called sampling units, which are assigned to strata of land-use and land-cover types. The resultant stratified sampling units are used as input into subsequent USDA sampling procedures. As a test, three counties in Missouri were chosen for application of the CAS procedures. Subsequent analysis indicates that CAS was five times faster in creating sampling units than the manual techniques were
Optimization and resilience of complex supply-demand networks
Acknowledgments This work was supported by NSF under Grant No. 1441352. SPZ and ZGH were supported by NSF of China under Grants No. 11135001 and No. 11275003. ZGH thanks Prof Liang Huang and Xin-Jian Xu for helpful discussions.Peer reviewedPublisher PD
Interpretation of Millikan Library's Vibrating Modes Using A Magneto Coil To Measure Phase Shifts
A new set of natural frequencies for the 9-story reinforced concrete Millikan Library building on the Caltech campus is computed using the observed phase shift between the driving force of a shaker installed on the buildingâs roof and structural response at resonance. The phase of the shakerâs output force was recorded by a magneto coil and magnet attached to the shakerâs rotating mechanism, and the phase of the structural response was obtained from acceleration time series recorded by an accelerometer on the roof. These new results refute previous studiesâ identification of the 3rd EW and 2nd torsional modes which used spectral analysis of forced and free vibrations, but did not consider the phase shift. In addition, the newly identified 3rd EW mode shape is independent of the other EW mode shapes, unlike previous findings. This new interpretation is compatible with results from subspace system identification based on two sets of earthquake records
The Community Seismic Network and Quake-Catcher Network: enabling structural health monitoring through instrumentation by community participants
A new type of seismic network is in development that takes advantage of community volunteers to install low-cost accelerometers
in houses and buildings. The Community Seismic Network and Quake-Catcher Network are examples of
this, in which observational-based structural monitoring is carried out using records from one to tens of stations in a single
building. We have deployed about one hundred accelerometers in a number of buildings ranging between five and 23
stories in the Los Angeles region. In addition to a USB-connected device which connects to the hostâs computer, we
have developed a stand-alone sensor-plug-computer device that directly connects to the internet via Ethernet or wifi. In
the case of the Community Seismic Network, the sensors report both continuous data and anomalies in local acceleration
to a cloud computing service consisting of data centers geographically distributed across the continent. Visualization
models of the instrumented buildingsâ dynamic linear response have been constructed using Google SketchUp and an
associated plug-in to matlab with recorded shaking data. When data are available from only one to a very limited number
of accelerometers in high rises, the buildings are represented as simple shear beam or prismatic Timoshenko beam models
with soil-structure interaction. Small-magnitude earthquake records are used to identify the first set of horizontal vibrational
frequencies. These frequencies are then used to compute the response on every floor of the building, constrained
by the observed data. These tools are resulting in networking standards that will enable data sharing among entire
communities, facility managers, and emergency response groups
Prediction of Wave Propagation in Buildings Using Data from a Single Seismometer
Crowdâsourced seismic networks in buildings collect important scientific data, in addition to allowing a diverse audience to visualize the vibrations of buildings. Visualization of a buildingâs deformation requires spatiotemporal interpolation of motions from seismometers that are located wherever the crowd places them. In many cases, a crowdâsourced building network may actually be just a single seismometer. A method to rapidly estimate the total displacement response of a building based on limited observational data, in some cases from only a single seismometer, is presented. In general, the earliest part of the response is simulated by assuming a vertically propagating shear wave. Later motions are simulated using mode shapes derived from a beam model (a shear beam, or more generally a Timoshenko beam), the parameters of which are determined from the ratios of the modal frequencies and the buildingâs exterior dimensions. The method is verified by (1) comparing predicted and actual records from a 54âstory building in downtown Los Angeles, California, and (2) comparing finiteâelement simulations of the 17âstory University of California, Los Angeles (UCLA) Factor building. The response of each of these buildings can be simulated with a simple shear beam. The importance of including the traveling wave part of the solution depends on the characteristics of the base ground shaking; the traveling wave becomes more apparent as the excitation becomes more impulsive. The method can be straightforwardly applied to multiple instrumented buildings, resulting in a tool to visualize linear elastic motions of those buildings
The chromatin remodeller ACF acts as a dimeric motor to space nucleosomes.
Evenly spaced nucleosomes directly correlate with condensed chromatin and gene silencing. The ATP-dependent chromatin assembly factor (ACF) forms such structures in vitro and is required for silencing in vivo. ACF generates and maintains nucleosome spacing by constantly moving a nucleosome towards the longer flanking DNA faster than the shorter flanking DNA. How the enzyme rapidly moves back and forth between both sides of a nucleosome to accomplish bidirectional movement is unknown. Here we show that nucleosome movement depends cooperatively on two ACF molecules, indicating that ACF functions as a dimer of ATPases. Further, the nucleotide state determines whether the dimer closely engages one or both sides of the nucleosome. Three-dimensional reconstruction by single-particle electron microscopy of the ATPase-nucleosome complex in an activated ATP state reveals a dimer architecture in which the two ATPases face each other. Our results indicate a model in which the two ATPases work in a coordinated manner, taking turns to engage either side of a nucleosome, thereby allowing processive bidirectional movement. This novel dimeric motor mechanism differs from that of dimeric motors such as kinesin and dimeric helicases that processively translocate unidirectionally and reflects the unique challenges faced by motors that move nucleosomes
The nucleon's octet axial-charge g_A^8 with chiral corrections
The value of the nucleon's flavour-singlet axial-charge extracted from
polarised deep inelastic scattering is sensitive to the value of the octet
axial-charge g_A^8 which is usually taken from an analysis of hyperon
beta-decays within the framework of SU(3) symmetry, namely 0.58 \pm 0.03. Using
the Cloudy Bag model we find that the value of g_A^8 is reduced by as much as
20% below the usual phenomenological value. This increases the value of the
flavour singlet axial charge (g_A^0|_inv) derived from deep inelastic data and
significantly reduces the difference between it and g_A^8.Comment: 12 page
The effect of 14 weeks of vitamin D3 supplementation on antimicrobial peptides and proteins in athletes
Heavy training is associated with increased respiratory infection risk and antimicrobial proteins are important in defence against oral and respiratory tract infections. We examined the effect of 14 weeks of vitamin D3 supplementation (5000 IU/day) on the resting plasma cathelicidin concentration and the salivary secretion rates of secretory immunoglobulin A (SIgA), cathelicidin, lactoferrin and lysozyme in athletes during a winter training period. Blood and saliva were obtained at the start of the study from 39 healthy men who were randomly allocated to vitamin D3 supplement or placebo. Blood samples were also collected at the end of the study; saliva samples were collected after 7 and 14 weeks. Plasma total 25(OH)D concentration increased by 130% in the vitamin D3 group and decreased by 43% in the placebo group (both P=0.001). The percentage change of plasma cathelicidin concentration in the vitamin D3 group was higher than in the placebo group (P=0.025). Only in the vitamin D3 group, the saliva SIgA and cathelicidin secretion rates increased over time (both P=0.03). A daily 5000 IU vitamin D3 supplement has a beneficial effect in up-regulating the expression of SIgA and cathelicidin in athletes during a winter training period which could improve resistance to respiratory infections
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Disrupted CXCR2 Signaling in Oligodendroglia Lineage Cells Enhances Myelin Repair in a Viral Model of Multiple Sclerosis.
CXCR2 is a chemokine receptor expressed on oligodendroglia that has been implicated in the pathogenesis of neuroinflammatory demyelinating diseases as well as enhancement of the migration, proliferation, and myelin production by oligodendroglia. Using an inducible proteolipid protein (Plp) promoter-driven Cre-loxP recombination system, we were able to assess how timed ablation of Cxcr2 in oligodendroglia affected disease following intracranial infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV). Generation of Plp-Cre-ER(T)::Cxcr2flox/flox transgenic mice (termed Cxcr2-CKO mice) allows for Cxcr2 to be silenced in oligodendrocytes in adult mice following treatment with tamoxifen. Ablation of oligodendroglia Cxcr2 did not influence clinical severity in response to intracranial infection with JHMV. Infiltration of activated T cells or myeloid cells into the central nervous system (CNS) was not affected, nor was the ability to control viral infection. In addition, the severity of demyelination was similar between tamoxifen-treated mice and vehicle-treated controls. Notably, deletion of Cxcr2 resulted in increased remyelination, as assessed by g-ratio (the ratio of the inner axonal diameter to the total outer fiber diameter) calculation, compared to that in vehicle-treated control mice. Collectively, our findings argue that CXCR2 signaling in oligodendroglia is dispensable with regard to contributing to neuroinflammation, but its deletion enhances remyelination in a preclinical model of the human demyelinating disease multiple sclerosis (MS).IMPORTANCE Signaling through the chemokine receptor CXCR2 in oligodendroglia is important for developmental myelination in rodents, while chemical inhibition or nonspecific genetic deletion of CXCR2 appears to augment myelin repair in animal models of the human demyelinating disease multiple sclerosis (MS). To better understand the biology of CXCR2 signaling on oligodendroglia, we generated transgenic mice in which Cxcr2 is selectively ablated in oligodendroglia upon treatment with tamoxifen. Using a viral model of neuroinflammation and demyelination, we demonstrate that genetic silencing of CXCR2 on oligodendroglia did not affect clinical disease, neuroinflammation, or demyelination, yet there was increased remyelination. These findings support and extend previous findings suggesting that targeting CXCR2 may offer a therapeutic avenue for enhancing remyelination in patients with demyelinating diseases
Projectable Horava-Lifshitz gravity in a nutshell
Approximately one year ago Horava proposed a power-counting renormalizable
theory of gravity which abandons local Lorentz invariance. The proposal has
been received with growing interest and resulted in various different versions
of Horava-Lifshitz gravity theories, involving a colourful potpourri of new
terminology. In this proceedings contribution we first motivate and briefly
overview the various different approaches, clarifying their differences and
similarities. We then focus on a model referred to as projectable
Horava-Lifshitz gravity and summarize the key results regarding its viability.Comment: 8 pages, no figures, to appear in the proceedings of First
Mediterranean Conference on Classical and Quantum Gravity Conference (MCCQG),
Kolymbari (Crete, Greece), September 14-18, 200
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