1,038 research outputs found
Extended calculations with spectroscopic accuracy : energy levels and radiative rates for O-like ions between Ar XI and Cr XVII
Using the multiconfiguration Dirac–Hartree–Fock and the relativistic configuration interaction methods, a consistent set of transition energies and radiative transition data for the main states of the 2s22p4, 2s2p5, 2p6, 2s22p33s, 2s22p33p, 2s22p33d, 2s2p43s, 2s2p43p, and 2s2p43d configurations in O-like Ions between Ar XI (Z=18) and Cr XVII (Z=24) is provided. Our data set is compared with the NIST compiled values and previous calculations. The data are accurate enough for identification and deblending of new emission lines from hot astrophysical and laboratory plasmas. The amount of data of high accuracy is significantly increased for the n=3 states of several O-like ions, where experimental data are very scarce
Blow up criterion for compressible nematic liquid crystal flows in dimension three
In this paper, we consider the short time strong solution to a simplified
hydrodynamic flow modeling the compressible, nematic liquid crystal materials
in dimension three. We establish a criterion for possible breakdown of such
solutions at finite time in terms of the temporal integral of both the maximum
norm of the deformation tensor of velocity gradient and the square of maximum
norm of gradient of liquid crystal director field.Comment: 22 page
A SUSY SU(5) Grand Unified Model of Tri-Bimaximal Mixing from A4
We discuss a grand unified model based on SUSY SU(5) in extra dimensions and
on the flavour group A4xU(1) which, besides reproducing tri-bimaximal mixing
for neutrinos with the accuracy required by the data, also leads to a natural
description of the observed pattern of quark masses and mixings.Comment: 19 page
Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer development through reciprocal regulation of the MAP kinase and TGF-β signaling pathways
Grainyhead-Like 2 (GRHL2) is an epithelial-specific transcription factor that regulates epithelial morphogenesis and differentiation. Prior studies suggested inverse regulation between GRHL2 and TGF-β in epithelial plasticity and potential carcinogenesis. Here, we report the role of GRHL2 in oral carcinogenesis in vivo using a novel Grhl2 knockout (KO) mouse model and the underlying mechanism involving its functional interaction with TGF-β signaling. We developed epithelial-specific Grhl2 conditional KO mice by crossing Grhl2 floxed mice with those expressing CreER driven by the K14 promoter. After induction of Grhl2 KO, we confirmed the loss of GRHL2 and its target proteins, while Grhl2 KO strongly induced TGF-β signaling molecules. When exposed to 4-nitroquinoline 1-oxide (4-NQO), a strong chemical carcinogen, Grhl2 wild-type (WT) mice developed rampant oral tongue tumors, while Grhl2 KO mice completely abolished tumor development. In cultured oral squamous cell carcinoma (OSCC) cell lines, TGF-β signaling was notably induced by GRHL2 knockdown while being suppressed by GRHL2 overexpression. GRHL2 knockdown or KO in vitro and in vivo, respectively, led to loss of active p-Erk1/2 and p-JNK MAP kinase levels; moreover, ectopic overexpression of GRHL2 strongly induced the MAP kinase activation. Furthermore, the suppressive effect of GRHL2 on TGF-β signaling was diminished in cells exposed to Erk and JNK inhibitors. These data indicate that GRHL2 activates the Erk and JNK MAP kinases, which in turn suppresses the TGF -β signaling. This novel signaling represents an alternative pathway by which GRHL2 regulates carcinogenesis, and is distinct from the direct transcriptional regulation by GRHL2 binding at its target gene promoters, e.g., E-cadherin, hTERT, p63, and miR-200 family genes. Taken together, the current study provides the first genetic evidence to support the role of GRHL2 in carcinogenesis and the underlying novel mechanism that involves the functional interaction between GRHL2 and TGF-β signaling through the MAPK pathways
Distribution and density of the partition function zeros for the diamond-decorated Ising model
Exact renormalization map of temperature between two successive decorated
lattices is given, and the distribution of the partition function zeros in the
complex temperature plane is obtained for any decoration-level. The rule
governing the variation of the distribution pattern as the decoration-level
changes is given. The densities of the zeros for the first two
decoration-levels are calculated explicitly, and the qualitative features about
the densities of higher decoration-levels are given by conjecture. The Julia
set associated with the renormalization map is contained in the distribution of
the zeros in the limit of infinite decoration level, and the formation of the
Julia set in the course of increasing the decoration-level is given in terms of
the variations of the zero density.Comment: 8 pages,8figure
Harmonic maps from degenerating Riemann surfaces
We study harmonic maps from degenerating Riemann surfaces with uniformly
bounded energy and show the so-called generalized energy identity. We find
conditions that are both necessary and sufficient for the compactness in
and modulo bubbles of sequences of such maps.Comment: 27 page
Parity Violating Measurements of Neutron Densities
Parity violating electron nucleus scattering is a clean and powerful tool for
measuring the spatial distributions of neutrons in nuclei with unprecedented
accuracy. Parity violation arises from the interference of electromagnetic and
weak neutral amplitudes, and the of the Standard Model couples primarily
to neutrons at low . The data can be interpreted with as much confidence
as electromagnetic scattering. After briefly reviewing the present theoretical
and experimental knowledge of neutron densities, we discuss possible parity
violation measurements, their theoretical interpretation, and applications. The
experiments are feasible at existing facilities. We show that theoretical
corrections are either small or well understood, which makes the interpretation
clean. The quantitative relationship to atomic parity nonconservation
observables is examined, and we show that the electron scattering asymmetries
can be directly applied to atomic PNC because the observables have
approximately the same dependence on nuclear shape.Comment: 38 pages, 7 ps figures, very minor changes, submitted to Phys. Rev.
Hybrid Stars in a Strong Magnetic Field
We study the effects of high magnetic fields on the particle population and
equation of state of hybrid stars using an extended hadronic and quark SU(3)
non-linear realization of the sigma model. In this model the degrees of freedom
change naturally from hadrons to quarks as the density and/or temperature
increases. The effects of high magnetic fields and anomalous magnetic moment
are visible in the macroscopic properties of the star, such as mass, adiabatic
index, moment of inertia, and cooling curves. Moreover, at the same time that
the magnetic fields become high enough to modify those properties, they make
the star anisotropic.Comment: Revised version with updated reference
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