205 research outputs found
PointAtrousGraph: Deep Hierarchical Encoder-Decoder with Point Atrous Convolution for Unorganized 3D Points
Motivated by the success of encoding multi-scale contextual information for
image analysis, we propose our PointAtrousGraph (PAG) - a deep
permutation-invariant hierarchical encoder-decoder for efficiently exploiting
multi-scale edge features in point clouds. Our PAG is constructed by several
novel modules, such as Point Atrous Convolution (PAC), Edge-preserved Pooling
(EP) and Edge-preserved Unpooling (EU). Similar with atrous convolution, our
PAC can effectively enlarge receptive fields of filters and thus densely learn
multi-scale point features. Following the idea of non-overlapping max-pooling
operations, we propose our EP to preserve critical edge features during
subsampling. Correspondingly, our EU modules gradually recover spatial
information for edge features. In addition, we introduce chained skip
subsampling/upsampling modules that directly propagate edge features to the
final stage. Particularly, our proposed auxiliary loss functions can further
improve our performance. Experimental results show that our PAG outperform
previous state-of-the-art methods on various 3D semantic perception
applications.Comment: 11 pages, 10 figure
On Optimal Neighbor Discovery
Mobile devices apply neighbor discovery (ND) protocols to wirelessly initiate
a first contact within the shortest possible amount of time and with minimal
energy consumption. For this purpose, over the last decade, a vast number of ND
protocols have been proposed, which have progressively reduced the relation
between the time within which discovery is guaranteed and the energy
consumption. In spite of the simplicity of the problem statement, even after
more than 10 years of research on this specific topic, new solutions are still
proposed even today. Despite the large number of known ND protocols, given an
energy budget, what is the best achievable latency still remains unclear. This
paper addresses this question and for the first time presents safe and tight,
duty-cycle-dependent bounds on the worst-case discovery latency that no ND
protocol can beat. Surprisingly, several existing protocols are indeed optimal,
which has not been known until now. We conclude that there is no further
potential to improve the relation between latency and duty-cycle, but future ND
protocols can improve their robustness against beacon collisions.Comment: Conference of the ACM Special Interest Group on Data Communication
(ACM SIGCOMM), 201
The Sources of Country and Industry Variations in ASEAN Stock Returns
This paper examines the possible determinants for the sources of variations in ASEAN stock returns across financial crises. Using a comprehensive data of 4043 firms from six ASEAN countries and 40 industries, we find that lagged country return and concentration are among the determinants that explain the country factors in the region, while size proved to be the determinant of industry factors for both tradable and non-tradable industries. In general, a higher previous return and lower industrial concentration would increase the country factor. We documented the loss of explanatory power of these determinants in the presence of crisis effects
Aging male symptoms scale (AMS) for health-related quality of life in aging men: translation and adaptation in Malay
The Aging Male Symptoms Scale (AMS) measures health-related quality of life in aging men. The objective of this paper is to describe the translation and validation of the AMS into Bahasa Melayu (BM). The original English version of the AMS was translated into BM by 2 translators to produce BM1 and BM2, and subsequently harmonized to produce BM3. Two other independent translators, blinded to the English version, back-translated BM3 to yield E2 and E3. All versions (BM1, BM2, BM3, E2, E3) were compared with the English version. The BM pre-final version was produced, and pre-tested in 8 participants. Proportion Agreement, Weighted Kappa, Spearman Rank Correlation Coefficient, and verbatim responses were used. The English and the BM versions showed excellent equivalence (weighted Kappa and Spearman Rank Coefficients, ranged from 0.72 to 1.00, and Proportion Agreement values ranged from 75.0% to 100%). In conclusion, the BM version of the AMS was successfully translated and adapted
Failure mechanisms of a SiC particles 2024Al composite under dynamic loading
Dynamic mechanical response of a 20 vol% silicon carbide particles (SiCp) reinforced 2024 Al composite prepared by powder metallurgy techniques were studied with a split Hopkinson bar. The fracture mechanisms and the deformation microstructure were examined with Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM). The present results indicate that the composite has a strong SiC-Al interfacial bonding; failure of the material is mainly caused by fracture of SiC particles and tearing failure of the SiC-Al interface. This failure by interface tearing with adhesion of an aluminium layer on SiC particles on the fracture surfaces has not been reported in SiC particle-reinforced aluminium composites. High-resolution transmission electron microscopy studies showed that many of the SiC-Al interfaces have coincident site lattice structures, which are considered to make a significant contribution to the strong interfacial bonding
Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity
BACKGROUND
Given the unceasing worldwide surge in COVID-19 cases, there is an imperative need to develop highly specific and sensitive serology assays to define exposure to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
METHODS
Pooled plasma samples from PCR positive COVID-19 patients were used to identify linear B-cell epitopes from a SARS-CoV-2 peptide library of spike (S), envelope (E), membrane (M), and nucleocapsid (N) structural proteins by peptide-based ELISA. Hit epitopes were further validated with 79 COVID-19 patients with different disease severity status, 13 seasonal human CoV, 20 recovered SARS patients and 22 healthy donors.
FINDINGS
Four immunodominant epitopes, S14P5, S20P2, S21P2 and N4P5, were identified on the S and N viral proteins. IgG responses to all identified epitopes displayed a strong detection profile, with N4P5 achieving the highest level of specificity (100%) and sensitivity (>96%) against SARS-CoV-2. Furthermore, the magnitude of IgG responses to S14P5, S21P2 and N4P5 were strongly associated with disease severity.
INTERPRETATION
IgG responses to the peptide epitopes can serve as useful indicators for the degree of immunopathology in COVID-19 patients, and function as higly specific and sensitive sero-immunosurveillance tools for recent or past SARS-CoV-2 infections. The flexibility of these epitopes to be used alone or in combination will allow for the development of improved point-of-care-tests (POCTs)
Teacher led school-based surveillance can allow accurate tracking of emerging infectious diseases - evidence from serial cross-sectional surveys of febrile respiratory illness during the H1N1 2009 influenza pandemic in Singapore
10.1186/1471-2334-12-336BMC Infectious Diseases12-BIDM
General Public’s knowledge, awareness, and perception of Cardiometabolic diseases: data from a Singapore study population
BackgroundHealth literacy and illness perception play crucial roles in tackling the cardiometabolic disease epidemic. We aim to compare the attitudes, knowledge, self-perceived risks and actions taken, between individuals with and without metabolic risk factors (MFs).MethodsFrom 5 June to 5 October 2022, participants of the general public were invited to complete a self-administered questionnaire. MF status was defined as the presence of hypertension, hyperlipidemia, diabetes mellitus and/or current/previous smoking. Participants were assessed based on four categories (knowledge-based, attitude-based, perceived risk, and action-based) of questions pertaining to four cardiometabolic diseases – diabetes mellitus, hypertension, hyperlipidemia, and non-alcoholic fatty liver disease.ResultsA total of 345 participants were enrolled, of whom 34.5% had at least one MF. Compared to those without MFs, participants with MFs had lower knowledge scores, but higher perceived risk scores across all cardiometabolic diseases. The largest knowledge gap pertained to hypertension-related questions. After adjustment, linear regression demonstrated that the presence of MFs (β:2.752, 95%CI: 0.772–4.733, p = 0.007) and higher knowledge scores (β:0.418, 95%CI: 0.236–0.600, p < 0.001) were associated with higher perceived risk. Despite increased perceived risk in those with MFs, this translated to only few increased self-reported preventive actions, when compared to those without MFs, namely the reduction in red meat/processed food consumption (p = 0.045) and increase in fruits/vegetables consumption (p = 0.009).ConclusionThis study identified a vulnerable subpopulation living with MFs, with high perceived risks, and discordant levels of knowledge and preventive actions taken. Nationwide efforts should be channeled into addressing the knowledge-to-action gap
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