885 research outputs found
Small ruminant production in the humid tropics
Research review on sheep and goat production in the humid zone of West Africa, w. respect to animal population, production parameters, reproduction, forage production, supplementary feeding based on agro - industrial byproducts, disease incidence, particularly peste petits ruminants & helminthiasis, housing, and economic aspects of small and large scale production, w. proposals for further research
Autonomous and controlled motivational regulations for multiple health related behaviors: between- and within-participants analyses
Self-determination theory has been applied to the prediction of a number of health-related behaviors with self-determined or autonomous forms of motivation generally more effective in predicting health behavior than non-self-determined or controlled forms. Research has been confined to examining the motivational predictors in single health behaviors rather than comparing effects across multiple behaviors. The present study addressed this gap in the literature by testing the relative contribution of autonomous and controlling motivation to the prediction of a large number of health-related behaviors, and examining individual differences in self-determined motivation as a moderator of the effects of autonomous and controlling motivation on health behavior. Participants were undergraduate students (N = 140) who completed measures of autonomous and controlled motivational regulations and behavioral intention for 20 health-related behaviors at an initial occasion with follow-up behavioral measures taken four weeks later. Path analysis was used to test a process model for each behavior in which motivational regulations predicted behavior mediated by intentions. Some minor idiosyncratic findings aside, between-participants analyses revealed significant effects for autonomous motivational regulations on intentions and behavior across the 20 behaviors. Effects for controlled motivation on intentions and behavior were relatively modest by comparison. Intentions mediated the effect of autonomous motivation on behavior. Within-participants analyses were used to segregate the sample into individuals who based their intentions on autonomous motivation (autonomy-oriented) and controlled motivation (control-oriented). Replicating the between-participants path analyses for the process model in the autonomy- and control-oriented samples did not alter the relative effects of the motivational orientations on intention and behavior. Results provide evidence for consistent effects of autonomous motivation on intentions and behavior across multiple health-related behaviors with little evidence of moderation by individual differences. Findings have implications for the generalizability of proposed effects in self-determination theory and intentions as a mediator of distal motivational factors on health-related behavior
Origins and evolution of stomatal development
The fossil record suggests stomata-like pores were present on the surfaces of land plants over 400 million years ago.
Whether stomata arose once or whether they arose independently across newly evolving land plant lineages has long been
a matter of debate. In Arabidopsis, a genetic toolbox has been identified that tightly controls stomatal development and
patterning. This includes the basic helix-loop-helix (bHLH) transcription factors SPEECHLESS (SPCH), MUTE, FAMA, and
ICE/SCREAMs (SCRMs), which promote stomatal formation. These factors are regulated via a signaling cascade, which
includes mobile EPIDERMAL PATTERNING FACTOR (EPF) peptides to enforce stomatal spacing. Mosses and hornworts,
the most ancient extant lineages to possess stomata, possess orthologs of these Arabidopsis (Arabidopsis thaliana) stomatal
toolbox genes, and manipulation in the model bryophyte Physcomitrella patens has shown that the bHLH and EPF
components are also required for moss stomatal development and patterning. This supports an ancient and tightly
conserved genetic origin of stomata. Here, we review recent discoveries and, by interrogating newly available plant
genomes, we advance the story of stomatal development and patterning across land plant evolution. Furthermore, we
identify potential orthologs of the key toolbox genes in a hornwort, further supporting a single ancient genetic origin of
stomata in the ancestor to all stomatous land plants
The effectiveness of structured sport and exercise interventions in enhancing the mental health of adolescents with mild to moderate mental health problems: a systematic review
Between 10% and 20% of adolescents globally have a diagnosed mental health disorder and a big proportion of individuals experience their first mental health problem during adolescence. However, limited research has investigated how an adult-led structured sport and exercise intervention can be used to support adolescents with mild to moderate mental health problems. A systematic review of the literature (five databases) was performed. Included studies (qualitative and quantitative) explored structured sport and exercise interventions aiming to help adolescents (aged 10–19 years) experiencing mild to moderate mental health problems. From 3506 studies screened, nine met the inclusion criteria (RCT = 6 and non-RCT = 3) following the PICOS, TIDieR frameworks and assessing quality of studies using the Mixed Methods Appraisal Tool. Activities included a group-based circuit training, high-intensity interval training, dance, group-based aerobic exercise, mindfulness-based Tai Chi Chuan and rugby. All included studies showed clinical improvements in adolescents’ anxiety or depression (anxiety, n = 5 and depression, n = 7). There is evidence that structured sport and exercise interventions can support adolescents with mild to moderate mental health problems. However, more research is needed to understand the mechanisms of how these outcomes are achieved, specifically using well-designed interventions tailored to specific exercises/sports, populations, and mental health outcomes
Origins and evolution of stomatal development
The fossil record suggests stomata-like pores were present on the surfaces of land plants over 400 million years ago.
Whether stomata arose once or whether they arose independently across newly evolving land plant lineages has long been
a matter of debate. In Arabidopsis, a genetic toolbox has been identified that tightly controls stomatal development and
patterning. This includes the basic helix-loop-helix (bHLH) transcription factors SPEECHLESS (SPCH), MUTE, FAMA, and
ICE/SCREAMs (SCRMs), which promote stomatal formation. These factors are regulated via a signaling cascade, which
includes mobile EPIDERMAL PATTERNING FACTOR (EPF) peptides to enforce stomatal spacing. Mosses and hornworts,
the most ancient extant lineages to possess stomata, possess orthologs of these Arabidopsis (Arabidopsis thaliana) stomatal
toolbox genes, and manipulation in the model bryophyte Physcomitrella patens has shown that the bHLH and EPF
components are also required for moss stomatal development and patterning. This supports an ancient and tightly
conserved genetic origin of stomata. Here, we review recent discoveries and, by interrogating newly available plant
genomes, we advance the story of stomatal development and patterning across land plant evolution. Furthermore, we
identify potential orthologs of the key toolbox genes in a hornwort, further supporting a single ancient genetic origin of
stomata in the ancestor to all stomatous land plants
Physics of Psychophysics: Stevens and Weber-Fechner laws are transfer functions of excitable media
Sensory arrays made of coupled excitable elements can improve both their
input sensitivity and dynamic range due to collective non-linear wave
properties. This mechanism is studied in a neural network of electrically
coupled (e.g. via gap junctions) elements subject to a Poisson signal process.
The network response interpolates between a Weber-Fechner logarithmic law and a
Stevens power law depending on the relative refractory period of the cell.
Therefore, these non-linear transformations of the input level could be
performed in the sensory periphery simply due to a basic property: the transfer
function of excitable media.Comment: 4 pages, 5 figure
Pleomorphic adenoma of the nasal septum
SummaryIntroductionPleomorphic adenoma is the most common benign tumour of the salivary glands. The major salivary glands are most commonly involved, or more rarely accessory salivary glands, especially the oral cavity. Other locations, such as the nasal cavity, paranasal sinuses or upper aerodigestive tract, are exceptional.Case reportA 26-year-old female presented with right-sided nasal obstruction. Radiology found a lesion involving the anterior third of the nasal septum. The patient underwent complete surgical resection of the tumour via an endonasal approach. Histological examination found a mixed cellular component (epithelial and myoepithelial) and mesenchymatous tissue with chondromyxoid stroma, enabling diagnosis of a typical pleomorphic adenoma.Discussion/ConclusionPleomorphic adenoma is exceptional in the nasal cavity, with only a few cases reported in the literature. Although benign, the risk of local recurrence, malignant transformation and metastasis requires close long-term follow-up
The Frail-LESS (LEss Sitting and Sarcopenia in Frail older adults) intervention to improve sarcopenia and maintain independent living via reductions in prolonged sitting: A randomised controlled feasibility trial protocol
Background
Sarcopenia is a progressive and generalised loss of muscle mass and function with advancing age and is a major contributor to frailty. These conditions lead to functional disability, loss of independence, and lower quality of life. Sedentary behaviour is adversely associated with sarcopenia and frailty. Reducing and breaking up sitting should thus be explored as an intervention target for their management. The primary aim of this study, therefore, is to examine the feasibility, safety, and acceptability of conducting a randomised controlled trial (RCT) that evaluates a remotely delivered intervention to improve sarcopenia and independent living via reducing and breaking up sitting in frail older adults.
Methods
This mixed-methods randomised controlled feasibility trial will recruit 60 community-dwelling older adults aged ≥ 65 years with very mild or mild frailty. After baseline measures, participants will be randomised to receive the Frail-LESS (LEss Sitting and Sarcopenia in Frail older adults) intervention or serve as controls (usual care) for 6 months. Frail-LESS is a remotely delivered intervention comprising of tailored feedback on sitting, information on the health risks of excess sitting, supported goal setting and action planning, a wearable device that tracks inactive time and provides alerts to move, health coaching, and peer support. Feasibility will be assessed in terms of recruitment, retention and data completion rates. A process evaluation will assess intervention acceptability, safety, and fidelity of the trial. The following measures will be taken at baseline, 3 months, and 6 months: sitting, standing, and stepping using a thigh-worn activPAL4 device, sarcopenia (via hand grip strength, muscle mass, and physical function), mood, wellbeing, and quality of life.
Discussion
This study will determine the feasibility, safety, and acceptability of evaluating a remote intervention to reduce and break up sitting to support improvements in sarcopenia and independent living in frail older adults. A future definitive RCT to determine intervention effectiveness will be informed by the study findings.
Trial registration
ISRCTN, ISRCTN17158017; Registered 6 August 2021, https://www.isrctn.com/ISRCTN17158017Abbeyfield Research Foundatio
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Sinking in : the peripheral Baldwinisation of human cognition
The Baldwin effect is a hypothetical process in which a learned response to environmental change evolves a genetic basis. Modelling has shown that the Baldwin effect offers a plausible and elegant explanation for the emergence of complex behavioural traits, but there is little direct empirical evidence for its occurrence. We highlight experimental evidence of the Baldwin effect and argue that it acts preferentially on peripheral rather than on central cognitive processes. Careful scrutiny of research on taste-aversion and fear learning, language, and imitation indicates that their efficiency depends on adaptively specialised input and output processes: analogues of scanner and printer interfaces that feed information to core inference processes and structure their behavioural expression
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