2,179 research outputs found

    A Comparison Of Student Performance In An Online Introductory Accounting Course With Traditional Classroom Students

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    Use of e-courses in higher education has become increasingly widespread in recent years.  Educators continue to debate the effectiveness of the technology and some argue that e-courses may be appropriate for some courses, but not for others.  Each discipline must determine the effectiveness of e-courses consistent with its own priorities.  Within accounting education, no consensus has been reached.  Recently, an opportunity to compare student performance in an e-course setting with that in a traditional classroom setting presented itself.  A professor taught the introductory accounting course in the two settings; classes were conducted in such a way that student performance could be compared.  This paper describes results and conclusions drawn from the comparisons

    Dexterous Orbital Servicing System (DOSS)

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    The Dexterous Orbiter Servicing System (DOSS) is a dexterous robotic spaceflight system that is based on the manipulator designed as part of the Flight Telerobotics Servicer program for the Space Station Freedom and built during a 'technology capture' effort that was commissioned when the FTS was cancelled from the Space Station Freedom program. The FTS technology capture effort yielded one flight manipulator and the 1 g hydraulic simulator that had been designed as an integrated test tool and crew trainer. The DOSS concept was developed to satisfy needs of the telerobotics research community, the space shuttle, and the space station. As a flight testbed, DOSS would serve as a baseline reference for testing the performance of advanced telerobotics and intelligent robotics components. For shuttle, the DOSS, configured as a movable dexterous tool, would be used to provide operational flexibility for payload operations and contingency operations. As a risk mitigation flight demonstration, the DOSS would serve the International Space Station to characterize the end to end system performance of the Special Purpose Dexterous Manipulator performing assembly and maintenance tasks with actual ISSA orbital replacement units. Currently, the most likely entrance of the DOSS into spaceflight is a risk mitigation flight experiment for the International Space Station

    Classification of Biomedical Signals using the Dynamics of the False Nearest Neighbours (DFNN) Algorithm

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    * This study was supported in part by the Natural Sciences and Engineering Research Council of Canada, and by the Gastrointestinal Motility Laboratory (University of Alberta Hospitals) in Edmonton, Alberta, Canada.Accurate and efficient analysis of biomedical signals can be facilitated by proper identification based on their dominant dynamic characteristics (deterministic, chaotic or random). Specific analysis techniques exist to study the dynamics of each of these three categories of signals. However, comprehensive and yet adequately simple screening tools to appropriately classify an unknown incoming biomedical signal are still lacking. This study is aimed at presenting an efficient and simple method to classify model signals into the three categories of deterministic, random or chaotic, using the dynamics of the False Nearest Neighbours (DFNN) algorithm, and then to utilize the developed classification method to assess how some specific biomedical signals position with respect to these categories. Model deterministic, chaotic and random signals were subjected to state space decomposition, followed by specific wavelet and statistical analysis aiming at deriving a comprehensive plot representing the three signal categories in clearly defined clusters. Previously recorded electrogastrographic (EGG) signals subjected to controlled, surgically-invoked uncoupling were submitted to the proposed algorithm, and were classified as chaotic. Although computationally intensive, the developed methodology was found to be extremely useful and convenient to use

    Femoral vectoring for hip dysplasia in neonates

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    The biomechanical factors influencing the reduction of dislocated hips with the Pavlik harness in patients of developmental hip dysplasia (DDH) were studied and simulated using a three-dimensional Finite Element Method (FEM) computer model. We identified five hip adductor muscles as key mediators in the prognosis of reduction for DDH, and determined the non-dimensional force contribution of each muscle in the direction necessary to achieve hip reduction for subluxated and fully dislocated hip joints. Results indicate that the effects of the muscles studied are functions of the severity of DDH. For an abducted and flexed subluxated hip, the Pectineus, Adductor Brevis, proximal Adductor Magnus, and Adductor Longus muscles aid reduction, while the portions of the Adductor Magnus muscle with middle and distal femoral insertion contribute negatively. For a fully dislocated hip all muscles contribute detrimentally. Consequently, our study points at the adductor muscles as the mediators of reductions of subluxated hips, and suggests the need for external traction to bring fully dislocated hips over the posterior acetabulum and labrum. Additionally, the reduction process of dysplastic hips was found to occur in two phases: (1) Release phase and (2) Reduction phase, and the muscles studied act distinctively in each phase. Moreover, we performed a cadaveric dissection to study the 3-dimensional orientation of the iliopsoas tendon in different hip configurations, and found that in hip abduction and flexion this tendon is likely not an obstruction to DDH reductions. We also report on the development of an improved three-dimensional anatomical computer model of the hip and femora of a 10-week old female infant for further study of hip dysplasia and other conditions of the hip using dynamic simulations and the Finite Element Method. This model was generated by combining CT-scans from four human subjects, as well as muscle positional data. It was segmented to encompass the distinct cartilaginous regions of infant anatomy, as well as the different regions of cortical and cancellous bone; these properties were retrieved from the literature. This engineering computer model of an infant anatomy is being employed f or ( 1) t he development of an anatomy-based finite element and dynamics computer model for simulations of hip dysplasia reductions using novel treatment approaches, (2) the determination of a path of least resistance in reductions of hip dysplasia based on a minimum potential energy approach, (3) the study of the mechanics of hyperflexion of the hip as alternative treatment for late-presenting cases of hip dysplasia, and (4) a comprehensive investigation of the effects of femoral anteversion angle (AV) variations in reductions of hip dysplasia. This study thus reports on an interdisciplinary effort between orthopedic surgeons and mechanical engineers to apply engineering fundamentals to solve medical problems. The results of this research are clinically relevant in pediatric orthopaedics

    Forearm and Distal Radius Fractures in Children

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    Pediatric forearm and distal radius fractures are common injuries. Resultant deformities are usually a product of indirect trauma involving angular loading combined with rotational displacement. Fractures are classified by location, completeness, angular and rotational deformity, and fragment displacement. Successful outcomes are based on restoration of adequate pronation and supina-tion and, to a lesser degree, acceptable cosmesis. When several important con-cepts are kept in mind, these goals are usually met with conservative treatment by reduction and immobilization. Greenstickfractures are reduced by rotating the forearm such that the palm is directed toward the fracture apex. Complete fractures are manipulated and reduced with traction and rotation; extremities are then immobilized in well-molded plaster casts until healing, which usually takes about 6 weeks. Radiographs should be obtained between 1 and 2 weeks after initial reduction to detect early angulation. In fractures at any level in children less than 9 years of age, complete displacement, 15 degrees of angulation, and 45 degrees of malrotation are acceptable. In children 9 years of age and older, 30 degrees of malrotation is acceptable, with 10 degrees of angulation for proximal fractures and 15 degrees for more distal fractures. Complete bayonet apposition is acceptable, especially for distal radius fractures, as long as angulation does not exceed 20 degrees and 2 years of growth remains. Operative intervention is used when the fracture is open and when acceptable alignment cannot be achieved or maintained. Single-bone intramedullary fixation has proved useful

    A Patient-Specific Model of the Biomechanics of Hip Reduction for Neonatal Developmental Dysplasia of the Hip: Investigation of Strategies for Low to Severe Grades of Developmental Dysplasia of the Hip

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    A physics-based computational model of neonatal Developmental Dysplasia of the Hip (DDH) following treatment with the Pavlik Harness (PV) was developed to obtain muscle force contribution in order to elucidate biomechanical factors influencing the reduction of dislocated hips. Clinical observation suggests that reduction occurs in deep sleep involving passive muscle action. Consequently, a set of five (5) adductor muscles were identified as mediators of reduction using the PV. A Fung/Hill-type model was used to characterize muscle response. Four grades (1–4) of dislocation were considered, with one (1) being a low subluxation and four (4) a severe dislocation. A three-dimensional model of the pelvis– femur lower limb of a representative 10 week-old female was generated based on CT-scans with the aid of anthropomorphic scaling of anatomical landmarks. The model was calibrated to achieve equilibrium at 901 flexion and 801 abduction. The hip was computationally dislocated according to the grade under investigation, the femur was restrained to move in an envelope consistent with PV restraints, and the dynamic response under passive muscle action and the effect of gravity was resolved. Model results with an anteversion angle of 501 show successful reduction Grades 1–3, while Grade 4 failed to reduce with the PV. These results are consistent with a previous study based on a simplified anatomically-consistent synthetic model and clinical reports of very low success of the PV for Grade 4. However our model indicated that it is possible to achieve reduction of Grade 4 dislocation by hyperflexion and the resultant external rotation

    Using Machine Learning to Diagnose Misaligned CT Scans

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    The usage of machine learning has grown exponentially in recent years; However, its applicable uses for medical diagnosis are still in an early stage. Conditions such as Developmental Dysplasia of the Hip (DDH), Cerebral Palsy (CP), and Femoracetabular Impingement (FAI) rely heavily on imaging techniques such as Ultrasound and Computed Tomography (CT) scans. Radiologists use multiple manually computed metrics using these images to diagnose conditions. This is time-intensive and requires an aligned image to get accurate diagnoses. The proposed application uses a deep learning detection algorithm to assist in the metric computation process. The algorithm is implemented using MATLAB R2023A and is trained on CT data gathered from 60 healthy participants. The algorithm performed well on images aligned according to the standard anteroposterior alignment used for radiological measurement. However, the variance of the metrics computation significantly increases when faced with severe misalignment in the craniocaudal or mediolateral axes. Additional algorithm improvements must be made to overcome this increased variance

    A connection between stress and development in the multicelular prokaryote Streptomyces coelicolor

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    Morphological changes leading to aerial mycelium formation and sporulation in the mycelial bacterium Streptomyces coelicolor rely on establishing distinct patterns of gene expression in separate regions of the colony. sH was identified previously as one of three paralogous sigma factors associated with stress responses in S. coelicolor. Here, we show that sigH and the upstream gene prsH (encoding a putative antisigma factor of sH) form an operon transcribed from two developmentally regulated promoters, sigHp1 and sigHp2. While sigHp1 activity is confined to the early phase of growth, transcription of sigHp2 is dramatically induced at the time of aerial hyphae formation. Localization of sigHp2 activity using a transcriptional fusion to the green fluorescent protein reporter gene (sigHp2–egfp) showed that sigHp2 transcription is spatially restricted to sporulating aerial hyphae in wild-type S. coelicolor. However, analysis of mutants unable to form aerial hyphae (bld mutants) showed that sigHp2 transcription and sH protein levels are dramatically upregulated in a bldD mutant, and that the sigHp2–egfp fusion was expressed ectopically in the substrate mycelium in the bldD background. Finally, a protein possessing sigHp2 promoter-binding activity was purified to homogeneity from crude mycelial extracts of S. coelicolor and shown to be BldD. The BldD binding site in the sigHp2 promoter was defined by DNase I footprinting. These data show that expression of sH is subject to temporal and spatial regulation during colony development, that this tissue-specific regulation is mediated directly by the developmental transcription factor BldD and suggest that stress and developmental programmes may be intimately connected in Streptomyces morphogenesis
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