543 research outputs found
Designing Medical Support for a Near-Earth Asteroid Mission
This panel will discuss the design of medical support for a mission to a near-Earth asteroid (NEA) from a variety of perspectives. The panelists will discuss the proposed parameters for a NEA mission, the NEA medical condition list, recommendations from the NASA telemedicine workshop, an overview of the Exploration Medical System Demonstration planned for the International Space Station, use of predictive models for mission planning, and mission-related concerns for behavioral health and performance. This panel is intended to make the audience aware of the multitude of factors influencing medical support during a NEA mission
Kinetics and Determining Factors of the Virologic Response to Antiretrovirals during Pregnancy
HIV-infected pregnant women with undetectable plasma HIV RNA concentrations at delivery pose a minimal risk of vertical transmission. We studied the kinetics and the determinants of the virologic response to antiretroviral therapy in 117 consecutive pregnancies. Patients who initiated therapy during pregnancy had a VL decrease of 2 and 2.5 log10 after 4 and 24 weeks, respectively. Therapeutic drug monitoring (TDM) of the protease inhibitors administered in doses recommended for nonpregnant adults resulted in below-target concentrations in 29%, 35%, and 44% of 1st, 2nd, and 3rd trimester measurements, respectively, but low drug concentrations did not correlate with virologic failure. Demographic characteristics, antiretroviral experience prior to pregnancy, baseline VL, or use of specific antiretrovirals did not affect the virologic response. Adherence to ≥95% of prescribed doses and utilization of psychosocial services were associated with undetectable plasma HIV RNA at delivery. In conclusion, the virologic responses of pregnant and nonpregnant adults share similar charactersitics
The number of transmission channels through a single-molecule junction
We calculate transmission eigenvalue distributions for Pt-benzene-Pt and
Pt-butadiene-Pt junctions using realistic state-of-the-art many-body
techniques. An effective field theory of interacting -electrons is used to
include screening and van der Waals interactions with the metal electrodes. We
find that the number of dominant transmission channels in a molecular junction
is equal to the degeneracy of the molecular orbital closest to the metal Fermi
level.Comment: 9 pages, 8 figure
'To live and die [for] Dixie': Irish civilians and the Confederate States of America
Around 20,000 Irishmen served in the Confederate army in the Civil War. As a result, they left behind, in various Southern towns and cities, large numbers of friends, family, and community leaders. As with native-born Confederates, Irish civilian support was crucial to Irish participation in the Confederate military effort. Also, Irish civilians served in various supporting roles: in factories and hospitals, on railroads and diplomatic missions, and as boosters for the cause. They also, however, suffered in bombardments, sieges, and the blockade. Usually poorer than their native neighbours, they could not afford to become 'refugees' and move away from the centres of conflict. This essay, based on research from manuscript collections, contemporary newspapers, British Consular records, and Federal military records, will examine the role of Irish civilians in the Confederacy, and assess the role this activity had on their integration into Southern communities. It will also look at Irish civilians in the defeat of the Confederacy, particularly when they came under Union occupation. Initial research shows that Irish civilians were not as upset as other whites in the South about Union victory. They welcomed a return to normalcy, and often 'collaborated' with Union authorities. Also, Irish desertion rates in the Confederate army were particularly high, and I will attempt to gauge whether Irish civilians played a role in this. All of the research in this paper will thus be put in the context of the Drew Gilpin Faust/Gary Gallagher debate on the influence of the Confederate homefront on military performance. By studying the Irish civilian experience one can assess how strong the Confederate national experiment was. Was it a nation without a nationalism
The Impact of Flavour Changing Neutral Gauge Bosons on B->X_s gamma
The branching ratio of the rare decay B->X_s gamma provides potentially
strong constraints on models beyond the Standard Model. Considering a general
scenario with new heavy neutral gauge bosons, present in particular in Z' and
gauge flavour models, we point out two new contributions to the B->X_s gamma
decay. The first one originates from one-loop diagrams mediated by gauge bosons
and heavy exotic quarks with electric charge -1/3. The second contribution
stems from the QCD mixing of neutral current-current operators generated by
heavy neutral gauge bosons and the dipole operators responsible for the B->X_s
gamma decay. The latter mixing is calculated here for the first time. We
discuss general sum rules which have to be satisfied in any model of this type.
We emphasise that the neutral gauge bosons in question could also significantly
affect other fermion radiative decays as well as non-leptonic two-body B
decays, epsilon'/epsilon, anomalous (g-2)_mu and electric dipole moments.Comment: 31 pages, 5 figures; version published on JHEP; added magic QCD
numbers for flavour-violating Z gauge boson contribution to B -> X_s gamm
Probing the charged Higgs boson at the LHC in the CP-violating type-II 2HDM
We present a phenomenological study of a CP-violating two-Higgs-doublet Model
with type-II Yukawa couplings at the Large Hadron Collider (LHC). In the light
of recent LHC data, we focus on the parameter space that survives the current
and past experimental constraints as well as theoretical bounds on the model.
Once the phenomenological scenario is set, we analyse the scope of the LHC in
exploring this model through the discovery of a charged Higgs boson produced in
association with a W boson, with the former decaying into the lightest neutral
Higgs and a second W state, altogether yielding a b\bar b W^+W^- signature, of
which we exploit the W^+W^- semileptonic decays.Comment: 37 pages, 16 figures; v2 updated treatment of LHC constraint
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