5,405 research outputs found

    Comment on the Calculation of the Angular Momentum and Mass for the (Anti-) Self Dual Charged Spinning BTZBTZ Black Hole

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    A recent paper [M. Kamata and T. Koikawa, Phys. Lett. {\bf B353} (1995) 196.] claimed to obtain the charged version of the (2+1)(2+1)-dimensional spinning BTZBTZ black hole solution by assuming a (anti-) self dual condition imposed on the electric and magnetic fields. We point out that the angular momentum and mass diverge at spatial infinity and as a consequence the solution is unphysicalComment: 4 pages, Latex, no figures, final version to be publised in Phys. Lett.

    Glp-1 as an adjunct to prolactin and anti-cd3 in type 1 diabetes treatment

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    Type 1 diabetes mellitus (T1DM) is an autoimmune disease where the destruction of the beta-cells causes insulin deficiency and hyperglycemia.  Many immune modulators have effectively prevented the further destruction of beta-cells in animal models of TIDM. However, due to the small beta-cell mass present at the time of diabetes, immune modulators (such as anti-CD3) have limited efficacy in treating T1DM in humans.  We hypothesize that addition of a growth factor that can augment beta-cell number (i.e. prolactin) and recruit stem cells (i.e. GLP-1) may improve effectiveness of immune modulator in inducing diabetes remission.  In our current study, we found that the diabetic NOD mice treated with anti-CD3+prolactin+GLP-1 had significantly higher diabetes remission rate in comparison to mice treated with anti-CD3+prolactin or anti-CD3 alone group.  This improvement in diabetes remission rate is accompanied by a higher glucose-stimulated insulin secretion rate. By performing immunohistochemistry (IHC), our results show that the anti-CD3+prolactin+GLP-1 group has a similar beta-cell fraction as the anti-CD3+prolactin group.  Future experiments determining the pancreatic insulin content and expression of GLUT2 would reveal the mechanism underlying novel therapeutic approach to improve the cure rates in children suffering from T1DM

    Spinning Black Holes in (2+1)-dimensional String and Dilaton Gravity

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    We present a new class of spinning black hole solutions in (2+1)(2+1)-dimensional general relativity minimally coupled to a dilaton with potential ebϕΛe^{b\phi}\Lambda. When b=4b=4, the corresponding spinning black hole is a solution of low energy (2+1)(2+1)-dimensional string gravity. Apart from the limiting case of the BTZBTZ black hole, these spinning black holes have no inner horizon and a curvature singularity only at the origin. We compute the mass and angular momentum parameters of the solutions at spatial infinity, as well as their temperature and entropy.Comment: 8 pages, Latex, statements about mass of 2+1 Hirschmann and Welch magnetic solution corrected, in press in Phys. Lett.

    The Effects of Training Load on Match Performance and Injury Incidence in an English Professional Soccer Club

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    Training load can be divided into 2 categories: internal and external training load. External training load is the physical stress work done by the athlete. External training load can be measured by the use of global positioning system (GPS) and video-based time motion analysis. Internal training load is the physiological responses from training sessions. It can be measured by the use of heart rate monitors and rate of perceived exertion. Monitoring training load can be used to measure the players' readiness for matches and as a precautionary measure to reduce overreach from training sessions. The aim of this thesis are to quantify training periodisation practices employed by a professional football club throughout a competitive season, determine the changes to microcycle training plan according to the number of matches in a week and the neuromuscular response during weekly microcycles of different football training and match loads among professional football players and to evaluate the eccentric hamstring strength and injury occurrence in relation to training load data throughout the competitive season. Study 1 aimed to quantify training periodisation practices employed by a professional football club throughout a competitive season. Initially, 20 players agreed to take part in the study, although only 12 players provided sufficient data to be included within the study. Training data was recorded via GPS across the competitive season, sub-divided into 4 different stages (each sub-divided into two 5-week blocks; early and late stage). Countermovement jump height was recorded for all players in order to assess their level of neuromuscular fatigue. Significant differences were observed in total distance covered (p = 0.045, effect size = 0.385) and high-speed distance covered (p = 0.001, effect size = 0.264) across the different stages of the season. There were no significant changes were observed in the training load as measured by the accumulated New Body Load (p = 0.085). A sub-analysis was conducted to explore the impact of fixture congestion on player training load by comparing weeks with 1 match, vs weeks with 2 matches. Significant differences were observed in total distance covered (1 match = 14076.16 ± 1569.24 m vs. 2 matches = 7874.35 ± 1923.01 m; t (3) =3.571, p = 0.038, 95% Confidence Interval of Difference [674.40 m to 11729.23 m], effect size = 3.53), high-speed distance covered (1 match = 781.49 ± 109.89 m vs. 2 matches = 413.99 ± 91.87 m; t (3) = 4.445, p = 0.021, 95% Confidence Interval of Difference [104.39 m to 630.60 m], effect size = 3.63) and accumulated New Body Load (1 match = 281.82 ± 35.36 AU vs 2 matches = 135.93 ± 12.02 AU; t (3) = 11.78, p = 0.001, 95% Confidence Interval of Difference [106.47 AU to 185.31 AU], effect size = 5.52) for training sessions in weeks that players were preparing for 1 match vs 2 matches. No correlation was found between the total distance covered (r = -0.001; p = 0.995), high-speed distance covered (r = 0.07; p = 0.547) and New Body Load (r = 0.101; p = 0.386) with countermovement jump height. It was concluded that there was a lack of manipulation in training sessions throughout the season. However, there were efforts to reduce the training load on weeks with 2 matches. Hence, alteration in training microcycles is important for players to be optimally prepared and recuperated for the following match. Study 2 aimed to evaluate the eccentric hamstring strength and injury occurrence in relation to training load data throughout the competitive season. Players were divided between those who had suffered hamstring injuries (n = 6) and those that did not during the season (n = 14) over the course of the season. They were required to perform isometric Nordic hamstring curl every week after a training session. No statistical differences were observed between the Nordic break-point angles (hamstring strength) of the two groups (p = 0.299). No significant changes were observed in the acute: chronic workload ratios between the two groups prior to injuries of the injured group (p = 0.316). It was concluded that eccentric hamstring strength and the acute: chronic workload ratios cannot be used to predict non-contact injury incidences. To conclude, the present results suggest that a lack of manipulation to training load may not reduce match running performances. However, coaches and sports scientists still manipulate and periodise training for optimal preparation for matches, especially in weeks with more matches. The use of eccentric hamstring strength tests alone and acute: chronic workload may not be suitable to predict non-contact injuries among the players

    Blockchain-based electronic voting protocol

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    Current electronic voting protocol require a centralized system to control the whole procedure from ballot inputs to result outputs and election monitoring. Meanwhile, blockchain technology provide a decentralized system which open across the whole network of untrusted participants. Applying blockchain technology into electronic voting protocol through a proper architecture can instil characteristic such as data confidentiality, data integrity and data authenticity. In this paper, we going to discuss a proposed method on how to leverage the advantages from blockchain into electronic voting protocol. This blockchain-based electronic voting protocol promise to provide a secure electronic election process given the proposed system works. We implement a protocol using blockchain to turn election protocol into an automated control system without relying any single point of entity. Lastly, we discuss the characteristics of our proposed blockchain-based electronic voting protocol in this paper. However, there are also emerging challenges and limitations awaiting to overcome. This paper gives a comprehensive overview of our proposed protocol

    Higher Dimensional Dilaton Black Holes with Cosmological Constant

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    The metric of a higher-dimensional dilaton black hole in the presence of a cosmological constant is constructed. It is found that the cosmological constant is coupled to the dilaton in a non-trivial way. The dilaton potential with respect to the cosmological constant consists of three Liouville-type potentials.Comment: 8 pages,to appear in Phys. Lett.

    Review on Leakage Resilient Key Exchange Security Model

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    In leakage resilient cryptography, leakage resilient key exchange protocols are constructed to defend against leakage attacks. Then, the key exchange protocol is proved with leakage resilient security model to determine whether its security proof can provide the security properties it claimed or to find out any unexamined flaw during protocol building. It is an interesting work to review the meaningful security properties provided by these security models. This work review how a leakage resilient security model for a key exchange protocol has been evolved over years according to the increasing security requirement which covers a different range of attacks. The relationship on how an adversary capability in the leakage resilient security model can be related to real-world attack scenarios is studied. The analysis work for each leakage resilient security model here enables a better knowledge on how an adversary query addresses different leakage attacks setting, thereby understand the motive of design for a cryptographic primitive in the security model

    Reemergence of Syphilitic Uveitis Masquerading as Other Diseases: A Report of Two Cases

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    During a 6-month period in 2010, 2 patients with uveitis were examined at our department and diagnosed with ocular syphilis. They initially presented with symptoms and signs resembling Harada's disease and Behçet's disease and were therefore treated with systemic steroids with suboptimal responses. When laboratory workup revealed neurosyphilis, they were given a course of intravenous penicillin G, which led to significant clinical and visual improvement. Epidemiological data indicates a worldwide reemergence of syphilis and a high degree of suspicion is necessary in view of its multitude of presenting ocular signs without pathognomonic features

    Charged Black Cosmic String

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    Global U(1) strings with cylindrical symmetry are studied in anti-de Sitter spacetime. According as the magnitude of negative cosmological constant, they form regular global cosmic strings, extremal black cosmic strings and charged black cosmic strings, but no curvature singularity is involved. The relationship between the topological charge of a neutral global string and the black hole charge is clarified by duality transformation. Physical relevance as straight string is briefly discussed.Comment: ll pages, LaTe
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