Solitary-wave description of condensate micro-motion in a time-averaged orbiting potential trap

We present a detailed theoretical analysis of micro-motion in a time-averaged orbiting potential trap. Our treatment is based on the Gross-Pitaevskii equation, with the full time dependent behaviour of the trap systematically approximated to reduce the trapping potential to its dominant terms. We show that within some well specified approximations, the dynamic trap has solitary-wave solutions, and we identify a moving frame of reference which provides the most natural description of the system. In that frame eigenstates of the time-averaged orbiting potential trap can be found, all of which must be solitary-wave solutions with identical, circular centre of mass motion in the lab frame. The validity regime for our treatment is carefully defined, and is shown to be satisfied by existing experimental systems.Comment: 12 pages, 2 figure

The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin

There is a continuing need to discover new bioactive natural products, such as antibiotics, in genetically-amenable micro-organisms. We observed that the enteric insect pathogen, Serratia marcescens Db10, produced a diffusible compound that inhibited the growth of Bacillis subtilis and Staphyloccocus aureus. Mapping the genetic locus required for this activity revealed a putative natural product biosynthetic gene cluster, further defined to a six-gene operon named alb1-alb6. Bioinformatic analysis of the proteins encoded by alb1-6 predicted a hybrid non-ribosomal peptide synthetase-polyketide synthase (NRPS-PKS) assembly line (Alb4/5/6), tailoring enzymes (Alb2/3) and an export/resistance protein (Alb1), and suggested that the machinery assembled althiomycin or a related molecule. Althiomycin is a ribosome-inhibiting antibiotic whose biosynthetic machinery had been elusive for decades. Chromatographic and spectroscopic analyses confirmed that wild type S. marcescens produced althiomycin and that production was eliminated on disruption of the alb gene cluster. Construction of mutants with in-frame deletions of specific alb genes demonstrated that Alb2-Alb5 were essential for althiomycin production, whereas Alb6 was required for maximal production of the antibiotic. A phosphopantetheinyl transferase enzyme required for althiomycin biosynthesis was also identified. Expression of Alb1, a predicted major facilitator superfamily efflux pump, conferred althiomycin resistance on another, sensitive, strain of S. marcescens. This is the first report of althiomycin production outside of the Myxobacteria or Streptomyces and paves the way for future exploitation of the biosynthetic machinery, since S. marcescens represents a convenient and tractable producing organism

Self-consistent pedestal prediction for JET-ILW in preparation of the DT campaign

The self-consistent core-pedestal prediction model of a combination of EPED1 type pedestal prediction and a simple stiff core transport model is able to predict Type I ELMy (edge localized mode) pedestals of a large JET-ILW (ITER-like wall) database at the similar accuracy as is obtained when the experimental global plasma beta is used as input. The neutral penetration model [R. J. Groebner et al., Phys. Plasmas 9, 2134 (2002)] with corrections that take into account variations due to gas fueling and plasma triangularity is able to predict the pedestal density with an average error of 15%. The prediction of the pedestal pressure in hydrogen plasma that has higher core heat diffusivity compared to a deuterium plasma with similar heating and fueling agrees with the experiment when the isotope effect on the stability, the increased diffusivity, and outward radial shift of the pedestal are included in the prediction. However, the neutral penetration model that successfully predicts the deuterium pedestal densities fails to predict the isotope effect on the pedestal density in hydrogen plasmas

Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis

Actinobacteria produce a variety of polyketide alkaloids with unusual structures. Recently, it was shown that a type I modular polyketide synthase (PKS) is involved in the assembly of coelimycin P1, a polyketide alkaloid produced by Streptomyces coelicolor M145. However, the mechanisms for converting the product of the PKS to coelimycin P1 remain to be elucidated. Here we show that the C-terminal thioester reductase (TR) domain of the PKS and an ω-transaminase are responsible for release of the polyketide chain as an aldehyde and its subsequent reductive amination. Bioinformatics analyses identified numerous gene clusters in actinobacterial genomes that encode modular PKSs with a C-terminal TR domain and a homolog of the ω-transaminase. These are predicted to direct the biosynthesis of both known and novel polyketide alkaloids, suggesting that reductive chain release and transamination constitutes a conserved mechanism for the biosynthesis of such metabolites

iPTF15eqv: Multi-wavelength Expos\'e of a Peculiar Calcium-rich Transient

The progenitor systems of the class of "Ca-rich transients" is a key open issue in time domain astrophysics. These intriguing objects exhibit unusually strong calcium line emissions months after explosion, fall within an intermediate luminosity range, are often found at large projected distances from their host galaxies, and may play a vital role in enriching galaxies and the intergalactic medium. Here we present multi-wavelength observations of iPTF15eqv in NGC 3430, which exhibits a unique combination of properties that bridge those observed in Ca-rich transients and Type Ib/c supernovae. iPTF15eqv has among the highest [Ca II]/[O I] emission line ratios observed to date, yet is more luminous and decays more slowly than other Ca-rich transients. Optical and near-infrared photometry and spectroscopy reveal signatures consistent with the supernova explosion of a < 10 solar mass star that was stripped of its H-rich envelope via binary interaction. Distinct chemical abundances and ejecta kinematics suggest that the core collapse occurred through electron capture processes. Deep limits on possible radio emission made with the Jansky Very Large Array imply a clean environment ($n <$ 0.1 cm$^{-3}$) within a radius of $\sim 10^{17}$ cm. Chandra X-ray Observatory observations rule out alternative scenarios involving tidal disruption of a white dwarf by a black hole, for masses > 100 solar masses). Our results challenge the notion that spectroscopically classified Ca-rich transients only originate from white dwarf progenitor systems, complicate the view that they are all associated with large ejection velocities, and indicate that their chemical abundances may vary widely between events.Comment: 24 pages, 16 figures. Closely matches version published in The Astrophysical Journa

A comparison of stochastic and effective medium approaches to the backscattered signal from a porous layer in a solid matrix

This article was published in the Journal of the Acoustical Society of America and is also available at: http://dx.doi.org/10.1121/1.3598461This paper reports a study of the backscattering behavior of a solid layer containing randomly spaced spherical cavities in the long wavelength limit. The motivation for the work arises from a need to model the responses of porous composite materials in ultrasonic NDE procedures. A comparison is made between models based on a summation over discrete scatterers, which show interesting emergent properties, and an integral formulation based on an ensemble average, and with a simple slab effective medium approximation. The similarities and differences between these three models are demonstrated. A simple quantitative criterion is established which sets the maximum frequency at which ensemble average or equivalent homogeneous medium models can represent echo signal generation in a porous layer for given interpore spacing, or equivalently, given pore size and concentration

Spectroscopy of High-Redshift Supernovae from the ESSENCE Project: The First Two Years

We present the results of spectroscopic observations of targets discovered during the first two years of the ESSENCE project. The goal of ESSENCE is to use a sample of ~200 Type Ia supernovae (SNe Ia) at moderate redshifts (0.2 < z < 0.8) to place constraints on the equation of state of the Universe. Spectroscopy not only provides the redshifts of the objects, but also confirms that some of the discoveries are indeed SNe Ia. This confirmation is critical to the project, as techniques developed to determine luminosity distances to SNe Ia depend upon the knowledge that the objects at high redshift are the same as the ones at low redshift. We describe the methods of target selection and prioritization, the telescopes and detectors, and the software used to identify objects. The redshifts deduced from spectral matching of high-redshift SNe Ia with low-redshift SNe Ia are consistent with those determined from host-galaxy spectra. We show that the high-redshift SNe Ia match well with low-redshift templates. We include all spectra obtained by the ESSENCE project, including 52 SNe Ia, 5 core-collapse SNe, 12 active galactic nuclei, 19 galaxies, 4 possibly variable stars, and 16 objects with uncertain identifications.Comment: 38 pages, 9 figures (many with multiple parts), submitted to A

Constraints on Cosmological Models from Hubble Space Telescope Observations of High-z Supernovae

We have coordinated Hubble Space Telescope photometry with ground-based discovery for three supernovae: two SN Ia near z~0.5 (SN 1997ce, SN 1997cj) and a third event at z=0.97 (SN 1997ck). The superb spatial resolution of HST separates each supernova from its host galaxy and leads to good precision in the light curves. The HST data combined with ground-based photometry provide good temporal coverage. We use these light curves and relations between luminosity, light curve shape, and color calibrated from low-z samples to derive relative luminosity distances which are accurate to 10% at z~0.5 and 20% at z=1. The redshift-distance relation is used to place constraints on the global mean matter density, Omega_matter, and the normalized cosmological constant, Omega_Lambda. When the HST sample is combined with the distance to SN 1995K (z=0.48), analyzed by the same precepts, it suggests that matter alone is insufficient to produce a flat Universe. Specifically, for Omega_matter+Omega_Lambda=1, Omega_matter is less than 1 with >95% confidence, and our best estimate of Omega_matter is -0.1 +/- 0.5 if Omega_Lambda=0. Although the present result is based on a very small sample whose systematics remain to be explored, it demonstrates the power of HST measurements for high redshift supernovae.Comment: Submitted to ApJ Letters, 3 figures, 1 plate, additional tabl