69 research outputs found

    Sorption Capacities of a Lignin-Based Electrospun Nanofibrous Material for Pharmaceutical Residues Remediation in Water

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    The threat of pharmaceutical residues in natural waters is a pressing concern in both developed and underdeveloped countries. Originating mostly from municipal and farms effluents, pharmaceuticals, poorly eliminated by traditional wastewater treatments enter the environment through sewage treatment plants discharges. Their adsorption on ecological adsorptive materials such as lignin may represent an interesting remediation solution. The present study sets out the sorption capacities and properties of a newly developed lignin-based nanofibrous material for typical pharmaceutical residues (fluoxetine, venlafaxine, ibuprofen, and carbamazepine) found in surface waters. This green biomaterial showed, in addition to its high recovery yield, excellent reusability through desorption (more than 90% recovered). As an example, adsorption levels reached 78 mg/g for adsorption of fluoxetine compared to 5–10, 49 and 75–80 for unfunctionalized silica, zeolites and ion-exchange resins respectively. The innovative approach reported therein perfectly meets the concept of circular economy sought in modern societies

    Pet recycling: From enzyme and process optimization to an industrial plant

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    Please click Additional Files below to see the full abstrac

    [(IMes)2Pt(H)(ClBC5H4SiMe3)] : a Borabenzene–Platinum Adduct with an Unusual Pt‐Cl‐B Interaction

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    A Pt‐Cl‐B interaction is observed when a borabenzene derivative reacts with a platinum(0) precursor with bulky N‐heterocyclic carbene ligands. The resulting platinum(II) complex (see picture; Pt red, N blue, Cl green, B pink, Si yellow) involves a new bonding mode for borabenzene, which usually binds in an η6 fashion to transition metals

    Prospectives

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    Tiré de: Prospectives, vol. 8, no 5, déc. 1972Titre de l'écran-titre (visionné le 24 janv. 2013

    Beneficial effects of reconstituted high-density lipoprotein (rHDL) on circulating CD34+ cells in patients after an acute coronary syndrome

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    Background: High-density lipoproteins (HDL) favorably affect endothelial progenitor cells (EPC). Circulating progenitor cell level and function are impaired in patients with acute coronary syndrome (ACS). This study investigates the short-term effects of reconstituted HDL (rHDL) on circulating progenitor cells in patients with ACS. Methods and Findings: The study population consisted of 33 patients with recent ACS: 20 patients from the ERASE trial (randomized to receive 4 weekly intravenous infusions of CSL-111 40 mg/kg or placebo) and 13 additional patients recruited as controls using the same enrolment criteria. Blood was collected from 16 rHDL (CSL-111)-treated patients and 17 controls at baseline and at 6–7 weeks (i.e. 2–3 weeks after the fourth infusion of CSL-111 in ERASE). CD34+ and CD34+/kinase insert domain receptor (KDR+) progenitor cell counts were analyzed by flow cytometry. We found preserved CD34+ cell counts in CSL-111-treated subjects at follow-up (change of 1.6%), while the number of CD34+ cells was reduced (-32.9%) in controls (p = 0.017 between groups). The level of circulating SDF-1 (stromal cell-derived factor-1), a chemokine involved in progenitor cell recruitment, increased significantly (change of 21.5%) in controls, while it remained unchanged in CSL-111-treated patients (p = 0.031 between groups). In vitro exposure to CSL-111 of early EPC isolated from healthy volunteers significantly increased CD34+ cells, reduced early EPC apoptosis and enhanced their migration capacity towards SDF-1. Conclusions: The relative increase in circulating CD34+ cells and the low SDF-1 levels observed following rHDL infusions in ACS patients point towards a role of rHDL in cardiovascular repair mechanisms

    Fibrilação atrial em atletas / Atrial fibrillation in athletes

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    Objetivos: Embasar na literatura a correlação existente na prĂĄtica de exercĂ­cios fĂ­sicos de alta potĂȘncia praticadas por atletas e a incidĂȘncia de fibrilação atrial. MĂ©todos: RevisĂŁo integrativa com artigos selecionados nas bases de dados Pubmed, Scielo, Medline e Lilacs publicados entre os anos de 2011 e 2021, com ensaios e estudos clĂ­nicos, alĂ©m de estudos observacionais. Os descritores utilizados foram: (athletes) AND (atrial fibrillation). Resultados: Alguns estudos apontaram uma baixa incidĂȘncia de fibrilação atrial entre atletas de elite. Enquanto outros constataram que o treinamento de alta intensidade de atletas competitivos estĂĄ relacionado a um maior risco de fibrilação atrial, principalmente homens saudĂĄveis de meia idade, quando possuem uma frequĂȘncia cardĂ­aca menor que 100 bpm. ConsideraçÔes finais: A Fibrilação atrial em atletas tem uma incidĂȘncia maior em atletas do sexo masculino e mais velhos que realizam treinos de alta intensidade, visto que possuem como potenciais indutores o remodelamento cardĂ­aco, a inflamação e a fibrose.

    Jules Romains' Vision of a United Europe in Interwar France: Legacy and Ambiguities

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    The interwar period in Europe was characterised by a multi-faceted movement in favour of European integration. After the slaughter of the First World War, many intellectuals, writers, industrialists and politicians brought the idea of European unity to the fore and engaged in various actions, from setting up organisations to lobbying governments, to promote the unification of Europe. Much research has been carried out on the leading figures of these pro-European activities but amongst the wealth of this period other actors have tended to be forgotten. Such is the case with the French writer Jules Romains, who not only coined “Europeanism”, the word that would define the whole movement in favour of Europe, but who also actively participated in promoting a united Europe. This article seeks to introduce and discuss Romains’ ideas on Europe. It will demonstrate that his vision was very coherent within the framework of his Unanimist philosophy but was undermined by serious ambiguities. It will also demonstrate that his ideas are of great interest for what they reveal about the interwar period in France and Europe, what they bring to the genealogy of the European project, as set up after the Second World War, and for the ambiguities at the core of his concept of Europe, which are still very much at the heart of many of today’s debates about the European Union
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