Management and Outcome of Cardiac and Endovascular Cystic Echinococcosis

Cardiac and vascular involvement are infrequent in classical cystic echinococcosis (CE), but when they occur they tend to present earlier and are associated with complications that may be life threatening. Cardiovascular CE usually requires complex surgery, so in low-income countries the outcome is frequently fatal. This case series describes the characteristics of cardiovascular CE in patients diagnosed and treated at a Tropical Medicine & Clinical Parasitology Center in Spain. A retrospective case series of 11 patients with cardiac and/or endovascular CE, followed-up over a period of 15 years (1995–2009) is reported. The main clinical manifestations included thoracic pain or dyspnea, although 2 patients were asymptomatic. The clinical picture and complications vary according to cyst location. Isolated cardiac CE may be cured after surgery, while endovascular extracardiac involvement is associated with severe chronic complications. CE should be included in the differential diagnosis of cardiovascular disease in patients from endemic areas. CE is a neglected disease and further studies are necessary in order to make more definite management recommendations for this rare and severe form of the disease. The authors propose a general approach based on cyst location: exclusively cardiac, endovascular or both

Thrombosis in vasculitis: from pathogenesis to treatment

In recent years, the relationship between inflammation and thrombosis has been deeply investigated and it is now clear that immune and coagulation systems are functionally interconnected. Inflammation-induced thrombosis is by now considered a feature not only of autoimmune rheumatic diseases, but also of systemic vasculitides such as Behçet’s syndrome, ANCA-associated vasculitis or giant cells arteritis, especially during active disease. These findings have important consequences in terms of management and treatment. Indeed, Behçet’syndrome requires immunosuppressive agents for vascular involvement rather than anticoagulation or antiplatelet therapy, and it is conceivable that also in ANCA-associated vasculitis or large vessel-vasculitis an aggressive anti-inflammatory treatment during active disease could reduce the risk of thrombotic events in early stages. In this review we discuss thrombosis in vasculitides, especially in Behçet’s syndrome, ANCA-associated vasculitis and large-vessel vasculitis, and provide pathogenetic and clinical clues for the different specialists involved in the care of these patients

Küreselleşme Sürecinde Oluşan Bölgeselleşme Hareketlerinde Türkiye’nin Diğer Ülkelerle İlişkileri Üzerine Bir Uygulama

Küreselleşme, artan insan hareketliliğini, bilginin, eşyaların (malların) ve paranın (sermayenin) ulusal sınırlar ötesinde dolaşımını tarif eden bir terim olup, bu terim 1980’lerde popüler olarak kullanılmaya başlanmıştır. Bu çalışmanın amacı, Türkiye’nin küreselleşme sürecinde içinde bulunduğu bazı bölgesel birleşmelerin ülkeye sağladığı katkının KOF ekonomik küreselleşme açısından değerlendirilmesidir. Bu amaçla, 1970-2014 dönemleri KOF ekonomik küreselleşme endeksi verileri kullanılarak ekonometrik modeller yardımıyla tahmin edilmiştir

Intracardiac masses

Between 1991 and 1998, 8 patients (mean age, 29.6 years) underwent surgery for an intracardiac mass. There were 2 hydatid cysts, 1 angiosarcoma, and 5 myxomas. One patient with myxoma underwent a Syme's amputation due to lower extremity ischemia caused by embolization. The patient with angiosarcoma died of cardiopulmonary failure on the 9th postoperative day. The surviving patients experienced no mortality, complications, or recurrence during follow-up of 0.5 to 5 years

Omentopexy in mediastinal infections: Case report Medi̇asti̇nal i̇nfeksi̇yonlarda omentum transpozi̇syonu tekni̇gi̇: Olgu sunumu

Omental transposition was performed on in two cases: a 43 year-old man with acute pericarditis who had no response to systemic antibiotics and pericardial tube drainage, and a 37 year-old woman who developed mediastinitis after mitral valve replacement. In this technique, the pedicled free omental graft was lied on contaminated area and the sternum reapproximated. There was no abdominal complication and both patients recovered rapidly and infection signs vanished completely

Carnitine levels in patients with chronic rheumatic heart disease

Objective: Carnitine, a small aminoacid derivative plays a major role in fatty acid oxidation. Myocardial carnitine deficiency may cause malfunction of the heart. Rheumatic valvular heart disease can be associated with myocardial dysfunction. We have investigated myocardial and plasma-free carnitine levels in patients with chronic rheumatic heart disease

A rare rib lesion due to parosteal osteosarcoma: a case report 11 medical and health sciences 1112 oncology and carcinogenesis

Introduction: Masses which develop on the surface of the rib bones are rare. The differential diagnosis includes benign and malignant lesions. Case presentation: A 23-year-old European woman presented at an out-patient clinic with a 9-month history of a painless swelling on the right posterolateral side of her chest wall. The case reported here is of a very rarely seen parosteal osteosarcoma of the rib that was treated with wide resection and chest wall reconstruction. There was no evidence of local recurrence or distal metastasis after a 1-year follow-up. Conclusion: Parosteal osteosarcoma is a locally aggressive malignant tumor, and resection with a wide margin is the most appropriate treatment. Correct diagnosis of parosteal osteosarcoma is challenging for an orthopedic surgeon. Although rare, in the differential diagnosis of lesions located on the ribs, parosteal osteosarcoma should be considered and a systematic diagnostic approach should be taken. © 2019 The Author(s)

A multidisciplinary approach to expand the use of pediatric ECLS systems in Turkey

PubMedID: 25626574[No abstract available