Prevalence of Helicobacter pylori in Children and Their Family Members in a District in Turkey

The aim of this study was to determine the prevalence of Helicobacter pylori among children and their family members and to evaluate some epidemiologic characteristics. The study included 275 children, aged 1-15 year(s), suffering from different gastrointestinal complaints. Blood serology and stool antigen testing were used for the diagnosis of infection due to H. pylori. Sixty-five (23.6%) of the 275 children were positive for H. pylori, and this positivity had a significantly increasing correlation with age (p<0.001). H. pylori-associated infection was observed among 45 (69.2%) and 17 (8%) mothers in the H. pylori-infected and non-infected groups respectively (p<0.0001). Most children and their families infected with H. pylori were living in an urban area. The findings suggest that infection due to H. pylori is a problem for this district area, and all children having any gastrointestinal complaints should be examined whether H. pylori was prevalent among their family members

An Extraordinary Cause of the Sucking Difficulty: Ecthyma Gangrenosum

Ecthyma gangrenosum is a cutaneous lesion often associated with pseudomonas aeruginosa bacteremia, even though it may develop without bacteremia and may originate from other bacterial and fungal organisms. Pseudomonas aeruginosa bacteremia or sepsis, which mainly affects immunocompromised patients, frequently occurs in hospitals. This lesion typically occurs on the extremities and gluteal and perineal regions. In this report we present a case of ecthyma gangrenosum in a premature newborn occurring secondary to pseudomonas sepsis causing sucking dysfunction due to tissue loss in the lip, soft palate, and tongue

The assessment of the knowledge and practices of healthcare providers regarding paroxysmal non-epileptic events (PNES) in children: A cross-sectional study

Objective: Paroxysmal non-epileptic events (PNEs) are a group of disorders that may be misdiagnosed as epilepsy. This study has aimed to assess the knowledge and practices of family physicians and pediatricians regarding the diagnosis, treatment, and follow-up of PNEs in children.Methods: The study was designed as a prospective cross-sectional study that was conducted between March 1, 2022, and June 1, 2022, by reaching pediatric specialists and assistants, family physicians, subspecialty assistants, and subspecialists using a Google questionnaire. The survey consists of 26 questions. The questionnaire used by the researchers was prepared in accordance with the literature search and it included detailed questions on the diagnosis, treatment, and differential diagnosis of PNEs.Results: A total of 37.3% worked as specialists. Most of the participants (41.3%) have worked in training and research hospitals, and 44.3% have been physicians for 6-10 years. The mean and standard deviation for the total score were 10.1 +/- 2.6. The scores of family physicians were statistically lower than those of specialists, subspecialty assistants, and subspecialists. A total of 67.2% left the decision of whether the patient should stop taking their medication to another clinician. 45% of the doctors said that they were uncomfortable with the diagnosis.Significance: The study findings emphasized the significant knowledge gap among healthcare providers regarding PNEs in children, highlighting the need for targeted educational interventions to improve their understanding and diagnostic skills in this area

Prevalence of Helicobacter pylori in Children and Their Family Members in a District in Turkey

The aim of this study was to determine the prevalence of Helicobacter pylori among children and their family members and to evaluate some epidemiologic characteristics. The study included 275 children, aged 1-15 year(s), suffering from different gastrointestinal complaints. Blood serology and stool antigen testing were used for the diagnosis of infection due to H. pylori. Sixty-five (23.6%) of the 275 children were positive for H. pylori, and thispositivity had a significantly increasing correlation with age (p&lt;0.001). H. pylori-associated infection was observed among 45 (69.2%) and 17 (8%) mothers in the H. pylori-infected and non-infected groups respectively (p&lt;0.0001). Most children and their families infected with H. pylori were living in an urban area. The findings suggest that infectiondue to H. pylori is a problem for this district area, and all children having any gastrointestinal complaints should be examined whether H. pylori was prevalent among their family members

Use of Complementary and Alternative Medicine Practices in Patients Admitted to The Pediatric Neurology Outpatient Clinic

Introduction: Despite the developments in pharmacologic treatments, traditional and complementary therapies have recently gained popularity in our country, as well as around the world. Aim: To question complementary and alternative medicine practices CAMP during clinical visits of pediatric neurology patients, to raise awareness of families and patients about the use of complementary and alternative medicine, and to prevent possible negative interactions. Methods: This prospective survey study was conducted with the parents of 300 pediatric patients aged between 6 months and 18 years, who were being treated at the Child Neurology Clinic between March 1st and May 30th, 2020. For the study, 360 patients’ parents who came to the Pediatric Neurology clinic for treatment were randomly selected, and a face-to-face survey lasting 2 minutes was conducted with 300 patients’ parents who agreed to participate in the study. This study was approved with the decision number E-20-12-62 at the meeting dated 21.12.2020 of the Clinical Research Ethics Committee of SBU Ankara Dr Sami Ulus Gynecology and Childhood Health and Diseases Training and Research Hospital. Results: Three hundred parents (56% women) participated in the study. Just over half (55.3%) of the patients were followed up with a diagnosis of epilepsy, 56.6% of the parents stated that they had used traditional and complementary therapy methods before, 43.4% stated that they did not use it, 46.54% stated that they used prayer and 23,9% used vitamin methods, respectively. Conclusion: In neurologic diseases, parents use traditional and complementary therapies as treatment methods, creating an alternative to modern medicine. Families and patients should be informed by investigating the reasons and frequency of using traditional and complementary therapies, raising the awareness of parents, and determining the possible harm caused by traditional and complementary therapies

Neurobiological Perspective and Personalized Treatment in Schizophrenia

Personalized treatment is the focus of researchers and comes into prominence for both genetic sciences and neurotechnology. Recently, clinical practice tries to follow the idea and principles of personalized medicine. Besides predicting an individual’s sensibility or predisposition for developing schizophrenia, pharmacogenetic and pharmacogenomic approaches attempt to define and acknowledge important indicators of clinical response to antipsychotics namely their efficacy and adverse effects. Particularly in the treatment of schizophrenia, clinicians are very helpless in resistant cases, and clinical pharmacogenomics contributes in a revolutionary way. With both phenotyping, namely Therapeutic Drug Monitoring (TDM) and genotyping, “big expectations” emerged both with the right drug, the right dose, and the right time. Both pharmacokinetic genotyping, CYP400 enzyme activity, and pharmacodynamic genotyping could be measured. The chapter handles schizophrenia with neurobiological views and covers personalized treatment approaches from various perspectives. Personalized treatment in the diagnosis and treatment of schizophrenia is presented first. Following comorbid schizophrenia in addition to the use of various substances, psychopharmacology of schizophrenia and the mechanism of action of antipsychotic drugs are presented. Genetics and epigenetics in schizophrenia are studied in detail and in silico application and computational approaches covering the feature extraction process and destructive impact of the metaverse are shared lastly

Interview with Marjorie Harkins Buchanan Kiewit

In this interview with Julia Stringfellow, Marjorie Harkins Buchanan Kiewit, LU class of 1943, discusses her time as a student as well as her time on the Board of Trustees.https://lux.lawrence.edu/oralhistories/1036/thumbnail.jp

An Empirical investigation on the relationship between The Eurozone zew index and The Eurozone stock markets

The aim of this study is to investigate the long and short term impact of the Euro ZEW index (ZEW) on the DAX (GDAXI) Germany, FTSE 100 (FTSE) the UK, CAC 40 (FCHI) France, OMXS30 Sweden and CROBEX (CRBEX) Croatia stock market indices using monthly data for the period between February 2008 and December 2020. The Euro ZEW Index was taken as the independent variable, and the index values of Eurozone stock markets were taken as the dependent variables. As a result of the study, the Euro ZEW index was found to have a positive (increasing) statistical significant effect on the DAX, FTSE, OMXS and CRBEX variables. Of the stock markets studied, Croatia CROBEX (CRBEX) index was the most affected index by the change in the Euro ZEW index. The least affected stock market was Germany DAX (GDAXI) index. The effect of the Euro ZEW Index on Euro stock markets was higher in the short-term, and gradually decreasing in the long term. The research findings are discussed in the conclusion section. © 2021 Nesrin Ceylan et al., published by Sciendo

The need for flexibility in work life an applied study

Günümüz koşullarında, küresel ve uluslar arası rekabet, çalışma hayatının yeniden şekillenmesini zorunluluk hale getirmiştir. Sanayileşmiş dünya ülkeleri, çalışma hayatı ve çalışanların bu hayata uyumu konusundaki çalışmaları ise; giderek hız kazanmıştır. Dünya da yaşanan küreselleşme, çalışma hayatı dışında sermaye ile hizmet sunumunun serbest hareket etmesine zemin oluşturmuştur. Bu nedenle birçok alanda olduğu gibi çalışma hayatı içinde de esnek sistemler bulunmaktadır. Esnek çalışma sistemi ve hayatı nedeni ile işgücü piyasası çok derinden etkilenmiş ve kaliteli iş gücü giderek azalmıştır. Artan işsizlik ile küreselleşmenin yarattığı istihdam açığı çalışanların sosyal hayatı ve iş hayatı üzerinde farklılıklar meydana getirmiştir. Esneklik, iş süresi, çalışma koşulları, ücretlendirme gibi faktörler esnek işgücünün işletme ve çalışan açısından şekillendirilmesi en fazla etki eden nedenlerdir. Yaptığımız bu çalışmada başta çalışanlar olmak üzere, iş hayatında yaşanan esneklik sürecinin çalışma hayatı üzerindeki etkileri belirlenmeye çalışılmıştır. Çalışmada model olarak ele alınan finans/banka sektöründe çalışanlar üzerinde LİKERT ölçekli bir anket uygulanmış, anketten elde edilen veriler SPSS-15 İstatistik programı ile analiz edilerek sonuç öneri çıkarılmıştır. Uygulamada kullanılan anket, farklı finans ve banka kurumlarında çalışanlara mail ve elden verilmek koşulu ile gönderilmiş, kimlik bilgileri gizli tutulmak koşulu ile anketler geri toplanmıştır. Ayrıca çalışma hayatında yaşanan esnekliğe duyulan ihtiyaçların mevzuat açısından da değerlendirilmesi gerçekleştirilmiştir.Global and international competition necessitated remodeling of work life in today’s conditions. Studies of industrialized world countries regarding work life and adjustment of employed people to this life have gained speed. Globalization all over the world formed a basis for free circulation of capital and service offer aside from the work life. Therefore there are flexible systems in work life as in many fields. Labor market has been deeply affected because of flexible working system and life and qualified labor force have been gradually decreased. Increased unemployment and employment gap created by globalization caused differences on social and work life of employed people. Factors such as flexibility, hour of work, working conditions and salary are the reasons which affected the remodeling of flexible labor force mostly in terms of businesses and employed people. In this study, the effects of flexibility process experienced in business life on work life and employed people particularly have been tried to be determined. A LİKERT scaled survey was applied on people working in finance/banking sector which were discussed as a model in the study, data obtained from the survey were analyzed with SPSS-15 statistics program and a conclusion-suggestion was made. The survey used in the application was sent to the individuals working in different finance and bank institutions by e-mail or by hand and then surveys were collected on condition that identity information is kept confidential. Besides the assessment of the need for flexibility experienced in work life were made in terms of the legislation

Antidepresanlara bağlı dermatolojik yan etki gelişen iki olgu sunumu

Birçok ilaç, cilt tepkilerine sebep olmaktadır. Psikotrop ilaçlara bağlı olarak gelişen cilt tepkileri ise daha yaygındır. Antidepresanların tüm dünyada en sık kullanılan ilaçlar arasında yer almakta, bununla birlikte antidepresanlara bağlı dermatolojik yan etkilerle giderek daha sık karşılaşılmaktadır. Bu yan etkiler genel olarak iyi huylu lezyonlar olmakla birlikte, nadiren ciddi cilt tepkileri ortaya çıkabilmektedir. Antidepresanlara bağlı dermatolojik yan etkilere ilişkin yayınlar genellikle olgu sunumları ile sınırlıdır. Bu makalede, biri “bupropion’a bağlı eritema multiforme”, diğeri de ”essitalopram’a bağlı akut ürtiker” olmak üzere antidepresana bağlı dermatolojik yan etki gelişen iki olguyu sunmayı amaçladı