Estudio de la epidemiología, diagnóstico y tratamiento de las miocardiopatías familiares en la población pediátrica de Valladolid

Las Miocardiopatías familiares son aquellas enfermedades del corazón que se caracterizan por tener una presentación familiar, una base genética y por poder ser causa de muerte súbita. El estudio genético ha ido evolucionando a lo largo de los años hasta desempeñar, actualmente, un papel fundamental en el manejo de estas enfermedades. El análisis realizado para este trabajo tiene como objetivo describir las principales características de las Miocardiopatías familiares en una muestra de la población pediátrica de Valladolid y confirmar la importancia del estudio genético en su abordaje. Se ha realizado un estudio descriptivo retrospectivo en una muestra de n=49 pacientes pertenecientes a ambas áreas de salud de la provincia de Valladolid. Este grupo de sujetos tiene edades comprendidas entre los 1 y los 17 años, pertenecen a ambos sexos y tienen como característica común fundamental estar diagnosticados de una miocardiopatía familiar. La estadística descriptiva realizada sobre esta muestra pone de manifiesto que se trata de un grupo de enfermedades con baja prevalencia (0,06%), sin asociación con el sexo y con una importante carga genética (estudio genético positivo en el 86,66% de los pacientes a los que se les solicita). La edad de diagnóstico no está claramente definida, pero el objetivo es identificar la patología de la manera más precoz posible. Como conclusión, las miocardiopatías familiares son enfermedades poco frecuentes, pero con gran repercusión en la vida de aquel que las padece y de sus familiares. Es fundamental progresar en el estudio de este tipo de cardiopatías, principalmente por su riesgo de producir muerte súbita, pues se pretende orientar el tratamiento hacia una terapia genética en el futuro.Grado en Medicin

Search for torsional oscillations in isolated sunspots

In this work we seek evidence for global torsional oscillations in alpha sunspots. We have used long time series of continuum intensity and magnetic field vector maps from the Helioseismic and Magnetic Imager (HMI) instrument on board the Solar Dynamics Observatory (SDO) spacecraft. The time series analysed here span the total disk passage of 25 isolated sunspots. We found no evidence of global long-term periodic oscillations in the azimuthal angle of the sunspot magnetic field within $\sim$ 1 degree. This study could help us to understand the sunspot dynamics and its internal structure

Yield determination in olive hedgerow orchards. I. Yield and profiles of yield components in north–south and east–west oriented hedgerows

A study of the vertical distribution of flowering and fruit set and of components of yield (fruit numbers, fruit size, and fruit oil content) was maintained for 2 years in N–S- and E–W-oriented olive hedgerows of comparable structure (row spacing 4m, hedgerow height to 2.5 m, width c. 1m) near Toledo, Spain (39.98N). Mean yield of the N–S orchard was 1854 kg oil/ha without difference between sides or years. Yield of the E–W orchard was greater in 2006, producing 2290 kg/ha, but only 1840 kg/ha in 2007, the same as the N–S orchard. The S side of the E–Worchard yielded more (59%) than the N side in 2007. In both orchards and years, most fruit was produced at 1.0–2.0m height and fruit density was the most influential component in these differences, reflecting more intense bud initiation in these upper layers. Other components that determined fruit number, fertile inflorescences, fruits per fertile inflorescence, and fruit drop were not significantly different between layers. Fruit characteristics depended on hedgerow position. In both N–S and E–W hedgerows, fruit high in the hedgerow was the largest, most mature, and with highest oil content. These differences were more marked in N–S than in E–W hedgerows. Fruit growth and development were concentrated from the middle of September until the end November. Oil content per fruit increased linearly during that period when 65% of final oil content was accumulated. Similar patterns were observed between sides. The results of yield and yield profiles are discussed in the general context of light interception. The results suggest the importance of hedgerow porosity, and distinct penetration patterns of direct-beam radiation through N–S and E–W hedgerows, as the basis for explanation of the high yield of the N side of E–W hedgerows

Yield determination in olive hedgerow orchards. II. Analysis of radiation and fruiting profiles

Profiles of fruit density, fruit size, and oil content were measured on 12 occasions in 7 olive orchards in Spain and 2 in Australia. Orchard structure varied widely. Height ranged from 2.0 to 5.5 m, row spacing from 3 to 6 m, and canopy width from 0.7 to 3m. Most orchards were oriented north–south (N–S) but one in Spain was oriented close to east–west (E–W)(208NE–SW). All orchards in Spain were cv. Arbequina, and in Australia they were cvv. Barnea and Picual. Analyses with a model of interception and transmission that estimated interception by individual sides of hedgerows revealed that fruit size and oil content were strongly related to intercepted radiation during the month before harvest across all orchards. Relationships were also evident between fruit density and interception but varied among orchards and years, indicating the importance of other environmental and probably physiological effects. In N–S orchards of cv. Arbequina, average fruit size and oil content increased linearly from 0.40 g (dry weight) to 0.72 g, and from 36 to 49% (of dry weight), as daily intercepted PAR increased from 6 to 25 mol/m2 (15–60% of horizontally incident radiation). The general principles of response extended to E–W orchards. There, it was shown that generally large fruit with high oil content on S sides was consistent with the plateau responses to radiation evident in the more extensive N–S data. On the N side, however, and accounting for transmission through the hedgerow, both fruit size and oil content were greater than in positions intercepting equivalent radiation inN–S orchards. Examples are provided of the utility of responses of fruit density, size, and oil content in establishing combinations of row height, row width, and row distance to improve or maintain productivity in some of the orchards included in the study

Production écrite à l'université : processus ou résultat?

Le travail dont nous allons vous faire part a été réalisé auprès des étudiants de la deuxième année de la Faculté des Langues (UNC) dans le cadre du projet de recherche « La compétence écrite en FLE : textes argumentatifs, repérage des difficultés, stratégies d’apprentissage et propositions pédagogiques ». Notre but principal est d’améliorer la compétence scripturale de nos apprenants et de faire face à la complexité qu’implique cette activité langagière. Il s’agit d’une expérience menée par deux chaires – Grammaire Française I et Langue Française II – dans le cadre du projet de recherche mentionné ci-dessus. La mise en place d’un test diagnostic à visée formative sera le point de départ de notre démarche pédagogique. Cette évaluation diagnostique sera accompagnée de trois phases de production comportant des rétroactions de remédiation. Notre intention est de réfléchir sur les stratégies, les ajustements et les modifications qui s’imposent sur le plan des compétences scripturales à développer chez nos étudiants.Fil: Moreyra, Ana Inés Alba. Universidad Nacional de Córdoba.Fil: Ferreira Centeno, Ana. Universidad Nacional de Córdoba

Effect of root-promoting products in the propagation of organic olive (Olea europaea L.) nursery plant

Olive cuttings root well using synthetic auxin indole-3-butyric acid (IBA). However, European and North American regulations do not allow the use of synthetic products to obtain organic vegetative propagation materials. In this work, we evaluated different products that could replace IBA in the propagation of olive cv. Cornicabra leafy-stem cuttings. In 2003, six products with a known auxin effect were assessed: IBA, algae extract, brewer's yeast, a bed of sunflower seed, seaweed dry extract (Sm-6 OrganicoTM), and an extract of macerated seeds (Terrabal OrganicoTM). The basal end of cuttings was treated with one of these products and placed on a mist bed with basal temperature control. After 2 months, rooting percentage, number of roots per cutting, number of cuttings with callus formation, and number of cuttings with basal thickening were determined. No significant differences were found in rooting percentage or number of roots per cutting between IBA and Terrabal OrganicoTM and Sm-6 OrganicoTM. These last products had significantly higher percentage of rooted cuttings without callus formation than IBA. In 2004, a new trial was conducted in which seven treatments were evaluated: IBA applied for 7 s; Terrabal OrganicoTM applied for 1, 4, and 8 h; and Sm-6 OrganicoTM applied for 1, 4, and 8 h. No significant differences in rooting percentage or number of roots per cutting were observed between IBA and Terrabal OrganicoTM applied for 1 h, whereas all the Sm-6 OrganicoTM treatments had significantly lower rooting percentages than IBA. Both rooting percentage and the percentage of rooted cuttings without callus development decreased significantly as treatment duration with Terrabal OrganicoTM increased. Therefore, Terrabal OrganicoTM could produce a toxic effect on cuttings when treatment duration is increased. Thus, Terrabal OrganicoTM could be a valid alternative to IBA in the propagation of organic olive plants of cv. Cornicabra when applied to the basal end of cuttings for 1

Relationship quality as antecedent of customer relationship proneness: a cross-cultural study between Spain and Mexico

Some factors such as the globalization and the development of information technologies are changing the dynamics of the relationship marketing bases. The new competitive framework defined by the relevance of online channels have caused the way of approaching relationship management with consumers to change. In this context, relationship quality (RQ) allows to understand the proneness of consumers to keep their commercial relations alive. Several are the studies that analyse RQ antecedents, but none has used a comprehensive management approach that includes resources and capabilities (such as market orientation or knowledge management), as perceived by customers, that a company has available for management in order to enhance said RQ in an online context. This work-in-progress aims to analyse the effect of said perceived quality on the consumer’s proneness to maintain the relationship under a cross-cultural context, considering the perceptions of Spanish and Mexican users of online banking services

Analysing relationship quality and its contribution to consumer relationship proneness

Relationship marketing has been the dominant paradigm in the sphere of marketing in the last decades. However, aspects such as globalisation, development of information technologies, or the growing competitiveness pressure have caused the way of approaching relationship management with consumers to change. A consumer feels as the lead character and demands personalised treatment customised to his/her needs and specific characteristics. In this context, relationship quality (RQ) allows to understand the proneness of consumers to keep their commercial relations alive. Several are the studies that analyse RQ antecedents, but none has used a comprehensive management approach that includes resources and capabilities (such as market orientation or knowledge management) that a company has available for management in order to enhance said RQ. Furthermore, we analyse the effect of said perceived quality on the consumer’s proneness to maintain the relationship

Estrategias Metodológicas que facilitan el proceso de enseñanza-aprendizaje de Geografía e Historia de la Educación Secundaria

El aprendizaje y utilización de los husos horarios representa una dificultad muy significativa para los estudiantes de octavo grado. Por tanto se ha desarrollado esta investigación documental con el propósito de destacar la importancias de las estrategias didácticas en el aprendizaje significativo de los husos horarios, para ello fue necesario identificar las estrategias didácticas que contribuyen al aprendizaje significativo de los mismos, describir las estrategias y dejar sentadas las bases de la importancia de estas estrategias en el aprendizaje significativo del tema en cuestión, en los estudiantes de octavo grado. Para la realización de esta investigación documental se realizaron múltiples consultas bibliográficas, obteniendo información relevante que nos permitió llevar a feliz término este trabajo investigativo. Entre los principales resultados podemos destacar que para que surja un aprendizaje significativo, se debe considerar no solo el momento de aprendizaje del estudiante, sino las características de los aprendices, la intensión de la estrategia, propósito del contenido, cómo, con qué y en qué condiciones se dará el aprendizaje y por último, el tiempo para la implementación de la estrategia. Las estrategias que contribuyen al aprendizaje significativo de los husos horarios, están ligadas a proceso cognitivos específicos, entre éstas se destacan, discusión guiada, conversación socrática, estudio de caso, ilustraciones gráficas, mapas y redes conceptuales, inclusión de conceptos. El verdadero aprendizaje significativo, se logra cuando el docente, utilizando estrategias didácticas adecuadas y oportunas, logra que el estudiante descubra y aplique nuevos conocimientos en situaciones de la vida diaria. Para ello, es necesario se establezcan nexos entre la teoría y la práctica, o sea, cuando luego de saber la teoría de los husos horarios comprenda que éstos son adaptables (flexibles) a las reglas de cada país