9 research outputs found

    Quantum Interference of Force

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    We show that a quantum particle subjected to a positive force in one path of a Mach-Zehnder interferometer and a null force in the other path may receive a negative average momentum transfer when it leaves the interferometer by a particular exit. In this scenario, an ensemble of particles may receive an average momentum in the opposite direction of the applied force due to quantum interference, a behavior with no classical analogue. We discuss some experimental schemes that could verify the effect with current technology, with electrons or neutrons in Mach-Zehnder interferometers in free space and with atoms from a Bose-Einstein condensate.Comment: 5 figures. Accepted in Quantum on 2018-12-0

    Bath-induced correlations lead to sub-shot-noise thermometry precision

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    We study the role of bath-induced correlations in temperature estimation of cold Bosonic baths. Our protocol includes multiple probes, that are not interacting, nor are they initially correlated to each other. They interact with a Bosonic sample and reach a non-equilibrium steady state, which is measured to estimate the temperature of the sample. It is well-known that in the steady state such non-interacting probes may get correlated to each other and even entangled. Nonetheless, the impact of these correlations in metrology has not been deeply investigated yet. Here, we examine their role for thermometry of cold Bosonic gases and show that, although being classical, bath-induced correlations can indeed lead to sub-shot-noise precision for thermometry at low temperatures; e.g., for a probe of 3030 non-interacting impurities they can enhance the quantum Fisher information by two orders of magnitude. The proposed thermometry scheme here does not require precise dynamical control of the probes and tuning the parameters, as it is build upon the non-equilibrium steady state of a non-interacting system. Our results put forward new possibilities in thermometry at low temperatures, of relevance for instance in cold gases and Bose--Einstein condensates.Comment: Comments are welcome

    Pattern of care and effectiveness of treatment for glioblastoma patients in the real world: Results from a prospective population-based registry. Could survival differ in a high-volume center?

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    BACKGROUND: As yet, no population-based prospective studies have been conducted to investigate the incidence and clinical outcome of glioblastoma (GBM) or the diffusion and impact of the current standard therapeutic approach in newly diagnosed patients younger than aged 70 years. METHODS: Data on all new cases of primary brain tumors observed from January 1, 2009, to December 31, 2010, in adults residing within the Emilia-Romagna region were recorded in a prospective registry in the Project of Emilia Romagna on Neuro-Oncology (PERNO). Based on the data from this registry, a prospective evaluation was made of the treatment efficacy and outcome in GBM patients. RESULTS: Two hundred sixty-seven GBM patients (median age, 64 y; range, 29-84 y) were enrolled. The median overall survival (OS) was 10.7 months (95% CI, 9.2-12.4). The 139 patients 64aged 70 years who were given standard temozolomide treatment concomitant with and adjuvant to radiotherapy had a median OS of 16.4 months (95% CI, 14.0-18.5). With multivariate analysis, OS correlated significantly with KPS (HR = 0.458; 95% CI, 0.248-0.847; P = .0127), MGMT methylation status (HR = 0.612; 95% CI, 0.388-0.966; P = .0350), and treatment received in a high versus low-volume center (HR = 0.56; 95% CI, 0.328-0.986; P = .0446). CONCLUSIONS: The median OS following standard temozolomide treatment concurrent with and adjuvant to radiotherapy given to (72.8% of) patients aged 6470 years is consistent with findings reported from randomized phase III trials. The volume and expertise of the treatment center should be further investigated as a prognostic factor

    Correction to: Which elderly newly diagnosed glioblastoma patients can benefit from radiotherapy and temozolomide? A PERNO prospective study (Journal of Neuro-Oncology, (2016), 128, 1, (157-162), 10.1007/s11060-016-2093-1)

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    The members of the PERNO Study Group were not individually captured in the metadata of the original publication. They are included in the metadata of this publication

    Blank spots on the map: some current questions on nuclear organization and genome architecture

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