The Effects of UV Exposure on the Antioxidant Enzyme Systems of Anemones

Superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) which are housekeeping enzymes protect cells from harmful side effects of reactive oxygen species (ROS). Anemonia sulcata var. smaragdina andAnemonia rustica are widely distributed along the Turkish coastlines of Aegean Sea. Recent studies showed that the environmental stresses such as elevated temperature, ultraviolet light, pathogen infection and decreased salinity might cause well known bleaching effects in Anemonia species. The effect of UV-light on antioxidant enzyme activities such as SOD, CAT, GSH-Px, protein levels and secondary pigments were determined in A. sulcata var. smaragdina and A. rustica. SOD, CAT, GSH-Px activities, protein levels and secondary pigments of these morphotypes were observed in both tentacles and columns separately. According to studies on bleaching, the elevated UV radiation may cause this bleaching event as a stress factor. However, in the present study no bleaching event was observed in anemone samples even they are exposed to 5 hours UV-exposure. Moreover, UV exposure did not change antioxidant systems remarkably. However, many investigations are still needed for obtaining the complete picture of the effects of UV-light on cellular pathways of cnidarian–algal symbiosis

Effects of Beta Vinasse Supplementation on Performance, Meat Quality and Ilio-Caecal Microflora in Quail Rations

The aim of this study was to evaluate the effects of Beta (?)-vinasse supplementation on the live weight (LW), live weight gain (LWG), feed intake (FI), feed conversion ratio (FCR), carcass yield, meat quality, and ilio-caecal bacteriological flora of quails. A total of 240 5-d-old Japanese (Coturnix coturnix Japonica) quails, including both males and females, were divided into 3 groups 80 quails and treated as follow: a control group (1) with 0 g ?-vinasse/ kg ration; (2) 15 g/kg ?-vinasse and (3) 30 g/kg ?-vinasse. The study lasted for 6 weeks. At the end of the experiment, supplementation with ?-vinasse did not have a significant effect on FI and FCR. Dietary supplementation with 30 g/ kg ?-vinasse significantly (P < 0.05) increased LW (21 d)and LWG (5 to 21 d). The dietary treatment of quails with different levels of ?-vinasse did not affect hot carcass weight, cold carcass weights, hot and cold carcass yields, and breast and thigh pH.The lightness (L*) and yellowness (b*) of breast values were significantly (P<0.05) increased by 30 g/kg supplementation. Different levels of ?-vinasse significantly increased Lactobacillus spp. in faeces. As a result, it was concluded that ?-vinasse (by-product obtained from molasses) can be used in quail diets as an alternative feed source that will meet the nutritional needs of the animal and have positive effects on the digestive system, especially on the intestinal health (an increase in Lactobacillus spp. counts). © 2023, Derya Yesilbag YeşilbağThe authors thank Integro for supplying the feed additive supplement

Pneumatic-probe measurement errors caused by fluctuating flow angles

Pneumatic probes such as five-hole probes (5HP) can conveniently measure three-dimensional flow angles, plus total and static pressure. In most applications, transducers are connected using pneumatic tubes, allowing the probe head to be highly miniaturized and robust. However, such “steady” probes are often used in unsteady flows, where they measure a pneumatically averaged flowfield that can differ from the time mean. To better understand these pneumatic averaging effects, an analytical framework is constructed using a quasi-steady model. Total and static pressure coefficients have a symmetric response to both positive and negative incidence. When incidence fluctuates, there is therefore a bias in the pneumatic average. These errors are evident in a shedding wake experiment, where a 5HP overestimates total pressure loss by up to 44% compared to a Kiel probe. These effects can be predicted by coupling an unsteady Reynolds-averaged Navier–Stokes calculation with the quasi-steady model. By predicting pneumatic averaging errors, the quasi-steady model can be used to obtain like-for-like validation of calculations against experimental data. Measurement data can also be corrected, provided that flow angle fluctuations can be measured or estimated. This approach can be readily used to postcorrect the large body of historical data likely to have been corrupted by pneumatic-averaging errors

Medicalization discourse and modernity: Contested meanings over childbirth in contemporary Turkey

In this article, we explore the increasing medicalization of birth and the surge in Caesarean sections in order to examine how this phenomenon relates to the dominant modernization discourse on women's lives in contemporary Turkey. We analyze women's modes of resistance and conformity to medicalization of birth through qualitative data from 15 focus groups of Turkish women as well as from physicians and midwives. We found out that Turkish women generally submit to medicalized birth, despite unpleasent experiences of hospital birth. We argue that the discourse of modernization and traditional patriarchy both play a role in women's submission to medicalization of birth; and we demonstrate the patterns through which these discourses collaborate in establishing the meaning of childbirth in Turkey. © Taylor & Francis Group, LLC

Computerized Nurse Charting

journal articleBiomedical Informatic

Hydrogels in the treatment of rheumatoid arthritis: drug delivery systems and artificial matrices for dynamic in vitro models

Rheumatoid arthritis (RA) is an autoimmune and chronic inflammatory disorder that mostly affects the synovial joints and can promote both cartilage and bone tissue destruction. Several conservative treatments are available to relieve pain and control the inflammation; however, traditional drugs administration are not fully effective and present severe undesired side effects. Hydrogels are a very attractive platform as a drug delivery system to guarantee these handicaps are reduced, and the therapeutic effect from the drugs is maximized. Furthermore, hydrogels can mimic the physiological microenvironment and have the mechanical behavior needed for use as cartilage in vitro model. The testing of these advanced delivery systems is still bound to animal disease models that have shown low predictability. Alternatively, hydrogel-based human dynamic in vitro systems can be used to model diseases, bypassing some of the animal testing problems. RA dynamic disease models are still in an embryonary stage since advances regarding healthy and inflamed cartilage models are currently giving the first steps regarding complexity increase. Herein, recent studies using hydrogels in the treatment of RA, featuring different hydrogel formulations are discussed. Besides, their use as artificial extracellular matrices in dynamic in vitro articular cartilage is also reviewed.Norte2020 project (NORTE-08-5369-FSE000044) and the Portuguese Foundation for Science and Technology (FCT) program (PD/BD/143081/2018). IFC thanks the TERM RES-Hub, Tissue Engineering and Regenerative Medicine Infrastructure project, funded by FCT. The FCT distinction attributed to JMO under the Investigator FCT program (number IF/01285/2015) is also greatly acknowledge

The state of the art development of AHP (1979-2017): A literature review with a social network analysis

Although many papers describe the evolution of the analytic hierarchy process (AHP), most adopt a subjective approach. This paper examines the pattern of development of the AHP research field using social network analysis and scientometrics, and identifies its intellectual structure. The objectives are: (i) to trace the pattern of development of AHP research; (ii) to identify the patterns of collaboration among authors; (iii) to identify the most important papers underpinning the development of AHP; and (iv) to discover recent areas of interest. We analyse two types of networks: social networks, that is, co-authorship networks, and cognitive mapping or the network of disciplines affected by AHP. Our analyses are based on 8441 papers published between 1979 and 2017, retrieved from the ISI Web of Science database. To provide a longitudinal perspective on the pattern of evolution of AHP, we analyse these two types of networks during the three periods 1979?1990, 1991?2001 and 2002?2017. We provide some basic statistics on AHP journals and researchers, review the main topics and applications of integrated AHPs and provide direction for future research by highlighting some open questions

The state of the art development of AHP (1979-2017): a literature review with a social network analysis

Although many papers describe the evolution of the analytic hierarchy process (AHP), most adopt a subjective approach. This paper examines the pattern of development of the AHP research field using social network analysis and scientometrics, and identifies its intellectual structure. The objectives are: (i) to trace the pattern of development of AHP research; (ii) to identify the patterns of collaboration among authors; (iii) to identify the most important papers underpinning the development of AHP; and (iv) to discover recent areas of interest. We analyse two types of networks: social networks, that is, co-authorship networks, and cognitive mapping or the network of disciplines affected by AHP. Our analyses are based on 8441 papers published between 1979 and 2017, retrieved from the ISI Web of Science database. To provide a longitudinal perspective on the pattern of evolution of AHP, we analyse these two types of networks during the three periods 1979–1990, 1991–2001 and 2002–2017. We provide some basic statistics on AHP journals and researchers, review the main topics and applications of integrated AHPs and provide direction for future research by highlighting some open questions

A novel black poplar propolis extract with promising health-promoting properties: focus on its chemical composition, antioxidant, anti-inflammatory, and anti-genotoxic activities

Propolis is a resinous mixture produced by honeybees which has been used since ancient times for its useful properties. However, its chemical composition and bioactivity may vary, depending on the geographical area of origin and the type of tree bees use for collecting pollen. In this context, this research aimed to investigate the total phenolic content (using the Folin-Ciocalteu assay) and the total antioxidant capacity (using the FRAP, DPPH, and ABTS assays) of three black poplar (Populus nigra L.) propolis (BPP) solutions (S1, S2, and S3), as well as the chemical composition (HPLC-ESI-MSn) and biological activities (effect on cell viability, genotoxic/antigenotoxic properties, and anti-inflammatory activity, and effect on ROS production) of the one which showed the highest antioxidant activity (S1). The hydroalcoholic BPP solution S1 was a prototype of an innovative, research-type product by an Italian nutraceutical manufacturer. In contrast, hydroalcoholic BPP solutions S2 and S3 were conventional products purchased from local pharmacy stores. For the three extracts, 50 phenolic compounds, encompassing phenolic acids and flavonoids, were identified. In summary, the results showed an interesting chemical profile and the remarkable antioxidant, antigenotoxic, anti-inflammatory and ROS-modulating activities of the innovative BPP extract S1, paving the way for future research. In vivo investigations will be a possible line to take, which may help corroborate the hypothesis of the potential health benefits of this product, and even stimulate further ameliorations of the new prototype.Propolis is a resinous mixture produced by honeybees which has been used since ancient times for its useful properties