Prevalence and distribution of oral mucosal lesions in an adult turkish population

Abstract Objectives: The purpose of this study was to assess the prevalence and distribution of oral mucosal lesions in a Turkish adult population.Material and methods: Five thousand consecutive patients were examined during routine dental treatment. Some of the mucosal changes were diagnosed solely by clinical examination. When clinical features were not diagnostic, a biopsy was undertaken. Chi-square test was used to analyze the data.Results: The overall incidence of oral mucosal changes or lesions was 15.5%. The lesions were classifi ed as anatomic changes, ulcerated lesions, tongue lesions, white lesions, benign lesions, color alterations, and malignant lesions. Anatomic changes (7%), ulcerated lesions (6.6%), and tongue lesions (4.6%) were the most common lesions.White lesions were observed in 2.2% of all patients. Among the white lesions, leukoplakia was identifi ed in men 4 times more frequently than it was in women. Benign lesions and color alterations were identifi ed in 1.6% and 1.2% of all patients, respectively. In addition, 3 patients (0.06%) were diagnosed as having squamous cell carcinoma, and 1 patient (0.02%) was diagnosed as having adenocarcinoma. There was a statistically signifi cant relation between smoking and the occurrence of mucosal lesions whereas no relation was found between alcohol consumption and mucosal lesion occurrence. Besides, no relation was found between systemic diseases and oral mucosal lesion occurrence.Conclusions: This study has provided information about the epidemiologic aspects of oral mucosal lesions that may prove valuable in planning of future oral health studies

Length-weight relationships of 28 fish species caught from demersal trawl survey in the Middle Black Sea, Turkey

This study provides updated the length-weight relationships and Fulton's condition factor of 28 fish species belonging to 23 families from the Black Sea. Samples were collected along the depths between 0-100 meters by demersal trawl surveys conducted seasonally from May 2017 to September 2019. A total of 83,885 specimens were collected. The length-weight relationships and Fulton's condition factor, minimum, maximum and mean lengths, total weights, descriptive statistics, and growth type were provided for all the species. The results indicate that LWR parameters of b varied from 2.2039 to 3.737 and Fulton's condition factor varied between 0.004 and 1.18. These findings could be useful for monitoring and management of sustainable fisheries and habitat health

Spondyloenchondrodysplasia Due to Mutations in ACP5: A Comprehensive Survey

Purpose: Spondyloenchondrodysplasia is a rare immuno-osseous dysplasia caused by biallelic mutations in ACP5. We aimed to provide a survey of the skeletal, neurological and immune manifestations of this disease in a cohort of molecularly confirmed cases. Methods: We compiled clinical, genetic and serological data from a total of 26 patients from 18 pedigrees, all with biallelic ACP5 mutations. Results: We observed a variability in skeletal, neurological and immune phenotypes, which was sometimes marked even between affected siblings. In total, 22 of 26 patients manifested autoimmune disease, most frequently autoimmune thrombocytopenia and systemic lupus erythematosus. Four patients were considered to demonstrate no clinical autoimmune disease, although two were positive for autoantibodies. In the majority of patients tested we detected upregulated expression of interferon-stimulated genes (ISGs), in keeping with the autoimmune phenotype and the likely immune-regulatory function of the deficient protein tartrate resistant acid phosphatase (TRAP). Two mutation positive patients did not demonstrate an upregulation of ISGs, including one patient with significant autoimmune disease controlled by immunosuppressive therapy. Conclusions: Our data expand the known phenotype of SPENCD. We propose that the OMIM differentiation between spondyloenchondrodysplasia and spondyloenchondrodysplasia with immune dysregulation is no longer appropriate, since the molecular evidence that we provide suggests that these phenotypes represent a continuum of the same disorder. In addition, the absence of an interferon signature following immunomodulatory treatments in a patient with significant autoimmune disease may indicate a therapeutic response important for the immune manifestations of spondyloenchondrodysplasia

New institutions of reform process; investment advisory councils

After the 1970s crises of capitalist system, profit rates of the capitalist were decreasing rapidly. In early capitalized countries all investment areas were not as profitable as it used to be. These countries, capitalists, need to find new investment areas and markets. Simultaneously late capitalized countries need more capital and investments in their economy. The needs of two sides are overlapping in the same period, but late capitalized country economies have high risks for capitalist class. Their laws and rules were not compatible with early capitalized countries. For this reason, foreign investment regimes have became an important topic for the late capitalized and early capitalized countries since 1970s. Since it was a necessity to establish proper structures as parallel to the aim of drawing more and more investment to the countries, the concept of ‘Improving investment climate’ gained a dominant position in debates on investment. The concept itself mainly refers to consisting necessary conditions in order for giving a new impetus to accumulation of capital. The institutions which run all these works have been named as Investment Advisory Councils. These Councils are also known as governance bodies which have actively been functioning in many countries in the last decade. These Councils are the most important institutions of reform process. Although these Councils have common targets, each institution in invidual countries has different characteristics specific to its own structure. In this study we are trying to define the concept of investment climate and main institution of ‘second generation‘ reform process. There is a big consensus in development studies of World Bank, IMF and OECD organisations. They argue that improving investment climate studies are for prosperity of everyone. In this study we are trying to show this process creates some loosers and winners. IAC institutions receive strong support from international organizations as well, it is possible to argue that improving investment climate in single countries is for the general interest of entire capitalist class. Ironically, these Councils define their targets as to make their countries the most competitive economy. Thus, it is apparent that two opposite tendencies exist in this process. In this study, it is aimed to understand how does IAC reach its targets which have been determined via two opposite tendencies. The reviews which will focus on IAC and YOIKK in Turkey consist the field of the research. Furthermore, the legislation which was introduced in the context of YOIKK will be analysed and the observations on the two opposite tendencies: competition and cooperation will also be integrated in to the study

Evaluation of Hydration Status of Obese Children A Pilot Study

WOS: 000445204102131

Two Siblings with Alstrom Syndrome

WOS: 000445204103155

Should Patients with Down Syndrome be Screened for Testicular Microlithiasis?

BackgroundTesticular microlithiasis (TM) is a rare condition characterized by asymptomatic calcification of seminiferous tubules and is considered as a precursor of testicular germ cell tumors. The prevalence of TM has been reported higher in patients with Down syndrome (DS) than general population. Our aim was to determine the prevalence of TM in our patients with DS

Anidulafungin induced reversible thrombocytopenia in a patient: A case report

Anidulafungin is a semisynthetic antifungal agent which is an echinocandin. Here, we presented elderly patient developed reversible severe thrombocytopenia due to anidulafungin. A 75-year-old man was admitted to the ICU with signs of hypovolemic shock and acute anemia. Amikacin therapy 15 mg/kg/day was started with the diagnosis of pneumonia due to the growth Acinetobacter baumannii. Amikacin therapy was discontinued in the treatment day 3 and began to colistin 2 mg/kg every 8 hours and imipenem 7 mg/kg every 6 hours. On hospital day 17, fluconazole 200mg/day was added to treatment due to candida albicans growth in blood culture and colistin-imipenem treatment was discontinued in the treatment. Candida albicans produced in control blood culture on floconazole therapy day 5 and the treatment was continued. Because of the increasing procalcitonin and CRP levels, liver enzyme elevation and fever 38.5 Co on fluconazole therapy day 6, anidulafungin therapy 200 mg was switched on fluconazole promptly. The dosage of anidulafungin was continued to 100 mg/day. Platelet counts was found to be six thousands anidulafungin therapy day 4. So treatment was terminated and liposomal amphotericin B treatment was started. Five days after the cessation of treatment with anidulafungin, platelets value was found to be over 100 thousand. Antifungal therapy was discontinued on liposomal amphotericin B therapy day 14, due not to the growth of microorganism in control blood culture. The patient who continue to be treated in intensive care, died due to multiorgan failure at 66 days. In conclusion; clinicians may consider monitoring platelets periodically, particularly in patients with hematologic disorders who use antibiotics and / or antifungal agents. [Med-Science 2018; 7(2.000): 456-8