Apprentissage assisté par Story Telling : une pédagogie de l'erreur

Les actes papiers peuvent être commandés à l'adresse suivant http://www.utc.fr/tice2004/commande_actes_tice2004.docThe experiment presented in this article is based on cognitive psychology studies dealing with the role of expectation failures in learning based on stories. The Interactive Learning Environments (ILE) which could derived from this approach are well fitted to the learning of behavioural competencies. We present an example of the usage of such a story-based learning system dedicated to the development of the social conducts of expert consultants.L'expérience présentée dans cet article s'appuie sur des études de psychologie cognitive portant sur le rôle des défaillances expectatives dans l'apprentissage à partir d'histoires. Les Environnements Informatiques d'Apprentissage Humain (EIAH) que l'on peut construire à partir de cette approche se révèlent bien adaptés à l'apprentissage des compétences comportementales. Nous présentons ici un exemple d'utilisation d'un tel système de formation à partir d'histoires dédié au développement des conduites sociales de consultants spécialisés

Apprentissage assisté par Story Telling : une pédagogie de l'erreur

Les actes papiers peuvent être commandés à l'adresse suivant http://www.utc.fr/tice2004/commande_actes_tice2004.docThe experiment presented in this article is based on cognitive psychology studies dealing with the role of expectation failures in learning based on stories. The Interactive Learning Environments (ILE) which could derived from this approach are well fitted to the learning of behavioural competencies. We present an example of the usage of such a story-based learning system dedicated to the development of the social conducts of expert consultants.L'expérience présentée dans cet article s'appuie sur des études de psychologie cognitive portant sur le rôle des défaillances expectatives dans l'apprentissage à partir d'histoires. Les Environnements Informatiques d'Apprentissage Humain (EIAH) que l'on peut construire à partir de cette approche se révèlent bien adaptés à l'apprentissage des compétences comportementales. Nous présentons ici un exemple d'utilisation d'un tel système de formation à partir d'histoires dédié au développement des conduites sociales de consultants spécialisés

An approach to standardize, automate omni-channel and AI transactional digital service creation

Our work is at the crossroads of two categories of technologies. On the one hand, omnichannel digit services, to address the needs of users in the most seamless way. On the other hand, low code approaches, to build simply even complex software applications. In this twofold context, we propose DSUL (Digital Service Universal Language). It allows to build omnichannel services with minimal work from their designers. We describe precisely how DSUL operates, and its innovation in regard to the state of the art. We also consider the various methods to evaluate this framework

Percepção de impacto em profundidade do curso técnico do Centro de Ensino Médio integrado à educação profissional (CEMI) : a visão dos egressos

Trabalho de Conclusão de Curso (graduação)—Universidade de Brasília, Faculdade de Administração, Contabilidade, Economia e Gestão de Políticas Públicas, Departamento de Administração, 2018.A presente pesquisa teve o objetivo de analisar a percepção de impacto em profundidade dos egressos do curso técnico do Centro de Ensino Médio Integrado à Educação Profissional (CEMI). As justificativas para esta pesquisa estão em âmbito social, institucional e acadêmicas. A partir dela será possível mensurar o impacto do curso, algo que nunca foi avaliado. Será possível verificar a qualidade do ensino na percepção dos egressos, e é importante, pois a escola sobrevive de recursos públicos. Academicamente é relevante por ser um campo pouco explorado. A metodologia utilizada foi qualitativa e quantitativa. A etapa qualitativa foi dedicada à análise do material didático do curso, para posterior elaboração e validação semântica de um questionário de avaliação de impacto em profundidade. Na etapa quantitativa, foi aplicado o questionário construído anteriormente, sendo que todos os itens foram associados à escala tipo Likert de 11 pontos, onde 0= nunca aplico e 10= sempre aplico. A amostra considerada válida para análise, selecionada por conveniência entre os egressos do curso no período de 2008-2017, obteve 81 respondentes. Foram realizadas análises estatísticas descritiva e inferencial não paramétrica dos dados por meio do software SPSS (Statical Package for the Social). Os resultados mostraram que, de modo geral, o treinamento apresentou impacto moderado de acordo com a percepção dos respondentes, com média 5,05 (CV= 0,39). Foram encontradas competências que podem ser consideradas transversais (genéricas) em termos de impacto na atuação do egresso, como “utilizar softwares utilitários e de apresentação”; e “utilizar as normas de metodologia científica para desenvolver projetos”. Esses resultados sugerem que o curso possui aderência moderada à atuação dos formandos, com potenciais relacionados às competências de “elaborar relatórios e documentos de acordo com as normas técnicas”; e “manusear o sistema operacional”, e limites ainda associados a competências consideradas pouco úteis, como “elaborar e implementar algoritmos em português estruturado”; e “integrar banco de dados com a linguagem de script para servidor”. Ao final, são apresentadas e discutidas as consequências institucionais, sociais e acadêmicas do trabalho, seus limites, bem como sugerida uma agenda de pesquisas futuras

Enantioselective Total Synthesis of FD-891

The enantioselective synthesis of FD-891 has been achieved with a longest linear sequence of 21 steps. The synthetic strategy involves the use of aldol additions of a chlorotitanium enolate of N-acylthiazolidinethiones as the key reaction to establish 6 of the 10 stereogenic centers. A key cross-metathesis and a late-stage Julia olefination serve to assemble three key subunits

Presentation and Preliminary Results of DROÏD Project: Development of a Distributed Optical Fibre Dosimeter

International audienceABSTRACT DROÏD project is intended to develop a distributed optical fibre dosimeter based on Radiation-Induced Attenua-tion (RIA). The RIA will be measured by a high resolution Optical Time Domain Reflectometry (OTDR) technique that allows to locate the irradiated fibre section. The first part of the project focuses on designing a high radiation sensitive fibre. As a preliminary work, the attenu-ation of several fibres with various compositions has been recorded in situ during and after irradiation. The experimental setup and RIA values are presented and discussed. Several dopants and their combinations have been identified as a good starting point to design a highly radiation sensitive fibre

Rester au Prêcheur

Face aux différents aléas naturels conjugués à la montée des eaux, comment réinventer nos modèles d’habiter ? La commune du Prêcheur, située au Nord-Caraïbes de la Martinique, est sujette à de nombreux phénomènes naturels plus ou moins récurrents. Habiter dans ce milieu engendre un risque potentiel. Les questions environnementales, liées aux risques, et foncières, liées à l’habitat informel, sont appelées à se conjuguer dans la conception de l’occupation du territoire. Au croisement de l’écologie et de l’économie, les dynamiques du milieu naturel deviennent les données pour faire projet. Dans un contexte fragile, le projet de territoire ne peut se représenter sous une forme unique et figée. Les phénomènes climatiques et les sociétés se transforment sur le temps long. Il devient nécessaire d’accepter dès aujourd’hui la mise en marche d’un processus qui ne pourra être prolongé par les générations futures que s’il a déjà été amorcé. Le projet se voit alors comme la vision d’une ambition à l’horizon 2100, qui se met en place par le biais de différents outils. Lorsqu’ils sont mis en relation, ils deviennent autant d’entrées possibles pour déclencher des actions afin que les habitants aussi bien que les élus construisent ensemble la vision d’un futur Prêcheur.In the face of different natural hazards combined with rising water levels, how should we rethink our modes of existence? The municipality of Le Prêcheur, located in Northern Caribbean region of Martinique, is subject to a wide variety of recurring natural events and living in such an environment entails potential risks. Environmental questions linked to these risks and land tenure issues relating to informal housing will have to be taken into consideration in future urban planning and land use projects. At the crossroads of ecology and economics, the dynamics of the natural environment provide data which need to be used in urban planning. In a fragile context, an urban planning project cannot be represented in a single set form. Climatic events and societies evolve over time making it necessary to accept the initiation of a process that may only be continued by future generations if it is implemented as from today. The project is intended to achieve its goals by 2100 and to be implemented by means of tools fostering joint actions by residents and elected representatives to build a vision of the future for Le Prêcheur

Phase II study of epirubicin, oxaliplatin and docetaxel combination in metastatic gastric or gastroesophageal junction adenocarcinoma

<p>Abstract</p> <p>Background</p> <p>This phase II study was designed to evaluate the activity and safety of a combination of epirubicin, oxaliplatin and docetaxel in metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma.</p> <p>Methods</p> <p>Forty patients with measurable distant metastases received epirubicin 50 mg/m², docetaxel 60 mg/m²followed by oxaliplatin 100 mg/m²on day 1 of each 21-day cycle. Primary end point was response rates (RR).</p> <p>Results</p> <p>All patients were evaluable. The overall RR was 47.5% (95% confidence interval (CI) 32–63). The disease control was 80%. Median time for response was 6 weeks. Median time to progression was 6.3 months (95% CI 5.4–7.2) and the median overall survival time was 12.1 months (95% CI 10.7–13.5). Grade 3/4 neutropenia occurred in 50% of patients with two episodes of febrile neutropenia (5%). Other non-hematological grade 3 toxicities included sensory neuropathy in two patiens (5%), vomiting and mucositis in two patients (5%) and diarrhea in one patient (2.5%).</p> <p>Conclusion</p> <p>The combination of epirubicin, oxaliplatin and docetaxel was found to be effective and well tolerated in patiens with metastatic gastric or GEJ adenocarcinoma and maybe an appropriate regimen to be used in the neoadjuvant setting and with molecularly targeted agents.</p

Pharmacogenetic prediction of clinical outcome in advanced colorectal cancer patients receiving oxaliplatin/5-fluorouracil as first-line chemotherapy

To determine whether molecular parameters could be partly responsible for resistance or sensitivity to oxaliplatin (OX)-based chemotherapy used as first-line treatment in advanced colorectal cancer (CRC). We studied the usefulness of the excision repair cross-complementing 1 (ERCC1), xeroderma pigmentosum group D (XPD), XRCC1 and GSTP1 polymorphisms as predictors of clinical outcome in these patients. We treated 126 CRC patients with a first-line OX/5-fluorouracil chemotherapeutic regimen. Genetic polymorphisms were determined by real-time PCR on an ABI PRISM 7000, using DNA from peripheral blood. Clinical response (CR), progression-free survival (PFS) and overall survival (OS) were evaluated according to each genotype. In the univariate analysis for CR, ERCC1-118 and XPD 751 polymorphisms were significant (P=0.02 and P=0.05, respectively). After adjustment for the most relevant clinical variables, only ERCC1-118 retained significance (P=0.008). In the univariate analysis for PFS, ERCC1-118 and XPD 751 were significant (P=0.003 and P=0.009, respectively). In the multivariant analysis, only the XPD 751 was significant for PFS (P=0.02). Finally, ERCC1-118 and XPD 751 polymorphisms were significant in the univariate analysis for OS (P=0.006 and P=0.015, respectively). Both genetic variables remained significant in the multivariate Cox survival analysis (P=0.022 and P=0.03). Our data support the hypothesis that enhanced DNA repair diminishes the benefit of platinum-based treatments