Broken World: New Perspectives on American Women Regionalists

This dissertation considers how American women writers responded to the changing perceptions about feminine nature, to an increasingly modern society, and to the shifting religious landscape in nineteenth-century America. The complex relationship between nineteenth-century women and religion is firmly illustrated in the works of three writers who were widely read during their time and yet have a very limited readership today: Mary Hallock Foote, Sarah Orne Jewett, and Gertrude Bonnin, also known as Zitkala-Ša. Each figure held a prominent position in the high-literary establishment of the late nineteenth century, and I show how each experimented with regional and sentimental literary conventions in order to entertain and appeal to a readership largely dominated by urban, upper-middle-class women. I argue that each of these writers constructed shared regional spaces and articulated spiritual values of place in order to dramatize differences between rural and urban cultures, to reflect concerns about America’s increasingly industrial, materialistic, and cosmopolitan mainstream society, and to create an anti-modern argument for a society grounded in Christian beliefs and practices. Despite the variety of their religious backgrounds and experiences, these writers all depict nuanced versions of Protestant tradition that both reflect the malleability of cultural religious constructions and re-assert Christian values of love, equality, family, and community. Moreover, through their descriptions of place—of the beauty, grandeur, isolation, and inherent risk of the natural world—these writers reveal phenomenological experiences and illuminate intricate connections between religion, place, and culture that contemporary scholars of religion and geography have only recently begun to explore

Some flight mechanics considerations for the Voyager mission

Voyager mission study considerations including launch opportunities, trajectory design, performance capability of Saturn V launch vehicle, and vehicle load relief contro

Completing College: National and State Reports

The national six-year college completion rate reached 62.2 percent, a 1.2 percentage point increase from last year. The completion rate increased regardless of starting institution types. Two-thirds of states increased at least 1 percentage point in completion rates over last year.This is the tenth report in the Completing College report series, featuring the completion rate trends nationally and for states, updated with the fall 2015 entering cohort's outcomes tracked through June 2021.The new longitudinal data dashboard offers national and multi-state comparisons through interactive visualizations and analysis tools. Underlying data are available online for downloading. The national eight-year completion rates are not included in the current report and will be published at a later time

A SUSTAINABLE APPROACH TO THE CONTROL OF PATHOGENS: THE FATE OF STREPTOCOCCI IN EQUINE COMPOST.

Streptococcus equi subspecies equi (S. equi), causes the potentially fatal respiratory disease called “strangles” in horses, while the closely related Streptococcus equi subspecies zooepidemicus (S. zooepidemicus) causes potentially fatal infections in humans. A study was undertaken to determine the survival of these two organisms in equine compost. Compost piles of equine bedding and feed waste were inoculated with 10 x 1010 c.f.u. of S. zooepidemicus and samples taken at 48, 96, 168 and 336 hours relative to samples placed in the pile at 0 hours. No Streptococci were isolated at 48 hours or subsequent time-points. Next, S. equi was similarly inoculated into equine compost, with samples taken at 2, 4, 8, 12, 24, 48, 168 and 336 hours later. No Streptococci were isolated at any time-point. To rule out killing of S. equi by microflora in equine waste, samples of soiled bedding, both autoclaved and un-autoclaved (with water added to match autoclaved moisture) were inoculated with 10 x 1010 c.f.u. of S. zooepidemicus and sampled at 0, 6, 12, 24, 48, 72, 120, 168 and 264 hours. In autoclaved bedding, S. zooepidemicus was isolated from 0 – 120 hours, but replaced by other flora at 264 hours. In un-autoclaved samples, Streptococci were not present after 48 hours. A repeated trial with S. equi yielded similar results. This data suggest that microbial activity of equine waste bedding may eliminate streptococci within 24 - 48 hours, indicating that normal microflora may provide sustainable methods for the control of human and animal pathogens

A SUSTAINABLE APPROACH TO THE CONTROL OF PATHOGENS: THE FATE OF STREPTOCOCCI IN EQUINE COMPOST.

Streptococcus equi subspecies equi (S. equi), causes the potentially fatal respiratory disease called “strangles” in horses, while the closely related Streptococcus equi subspecies zooepidemicus (S. zooepidemicus) causes potentially fatal infections in humans. A study was undertaken to determine the survival of these two organisms in equine compost. Compost piles of equine bedding and feed waste were inoculated with 10 x 1010 c.f.u. of S. zooepidemicus and samples taken at 48, 96, 168 and 336 hours relative to samples placed in the pile at 0 hours. No Streptococci were isolated at 48 hours or subsequent time-points. Next, S. equi was similarly inoculated into equine compost, with samples taken at 2, 4, 8, 12, 24, 48, 168 and 336 hours later. No Streptococci were isolated at any time-point. To rule out killing of S. equi by microflora in equine waste, samples of soiled bedding, both autoclaved and un-autoclaved (with water added to match autoclaved moisture) were inoculated with 10 x 1010 c.f.u. of S. zooepidemicus and sampled at 0, 6, 12, 24, 48, 72, 120, 168 and 264 hours. In autoclaved bedding, S. zooepidemicus was isolated from 0 – 120 hours, but replaced by other flora at 264 hours. In un-autoclaved samples, Streptococci were not present after 48 hours. A repeated trial with S. equi yielded similar results. This data suggest that microbial activity of equine waste bedding may eliminate streptococci within 24 - 48 hours, indicating that normal microflora may provide sustainable methods for the control of human and animal pathogens

An ecological method for the sampling of nonverbal signalling behaviours of young children with profound and multiple learning disabilities (PMLD)

- Background: Profound and multiple learning disabilities (PMLD) are a complex range of disabilities that affect the general health and wellbeing of the individual and their capacity to interact and learn. - Method: We developed a new methodology to capture the nonsymbolic signalling behaviours of children with PMLD within the context of a face-to-face interaction with a caregiver to provide analysis at a micro-level of descriptive detail incorporating the use of the ELAN digital video software. - Conclusion: The signalling behaviours of participants in a natural, everyday interaction can be better understood with the use of this innovation in methodology, which is predicated on the ecology of communication. Recognition of the developmental ability of the participants is an integral factor within that ecology. The method presented establishes an advanced account of the modalities through which a child affected by PMLD is able to communicate

Assessment of erosion and surface tritium inventory issues for the ITER divertor

The authors analyzed sputtering erosion and tritium codeposition for the ITER vertical target divertor design using erosion and plasma codes (WBC/REDEP/DEGAS+) coupled to available materials data. Computations were made for a beryllium, carbon, and tungsten coated divertor plate, and for three edged plasma regimes. New data on tritium codeposition in beryllium was obtained with the TPE facility. This shows codeposited H/Be ratios of the order of 10% for surface temperatures {le} 300 C, beryllium thereby being similar to carbon in this respect. Hydrocarbon transport calculations show significant loss (10--20%) of chemically sputtered carbon for detached conditions (T{sub e} {approx} 1 eV at the divertor), compared to essentially no loss (100% redeposition) for higher temperature plasmas. Calculations also show a high, non-thermal, D-T molecular flux for detached conditions. Tritium codeposition rates for carbon are very high for detached conditions ({approximately} 20g-T/1000 s discharge), due to buildup of chemically sputtered carbon on relatively cold surfaces of the divertor cassette. Codeposition is lower ({approximately} 10X) for higher edge temperatures ({approximately} 8--30 eV) and is primarily due to divertor plate buildup of physically sputtered carbon. Peak net erosion rates for carbon are of order 30 cm/burn-yr. Erosion and codeposition rates for beryllium are much lower than for carbon at detached conditions, but are similar to carbon for the higher temperatures. Both erosion and tritium codeposition are essentially nil for tungsten for the regimes studied

Selective serotonin reuptake inhibitors and clozapine: Clinically relevant interactions and considerations

The monoamine hypothesis of depression attributes the symptoms of major depressive disorders to imbalances of serotonin, noradrenaline, and dopamine in the limbic areas of the brain. The preferential targeting of serotonin receptor (SERT) by selective serotonin reuptake inhibitors (SSRIs) has offered an opportunity to reduce the range of these side effects and improve patient adherence to pharmacotherapy. Clozapine remains an effective drug against treatment-resistant schizophrenia, defined as failing treatment with at least two different antipsychotic medications. Patients with schizophrenia who display a constellation of negative symptoms respond poorly to antipsychotic monotherapy. Negative symptoms include the diminution of motivation, interest, or expression. Conversely to the depressive symptomology of interest presently, supplementation of antipsychotics with SSRIs in schizophrenic patients with negative symptoms lead to synergistic im-provements in the function of these patients. Fluvoxamine is one of the most potent inhibitors of CYP1A2 and can lead to an increase in clozapine levels. Similar increases in serum clozapine were detected in two patients taking sertraline. However, studies have been contradictory as well, show-ing no such increases, which are worrying. Clinicians should be aware that clozapine levels should be monitored with any coadministration with SSRIs