Las algas desmidiáceas como indicadoras: Mateyuca y Flor amarilla, dos morichales testigo de la biodiversidad del Orinoco

Fil: Duque, Santiago R.. Instituto Amazónico de Investigaciones. Imani. Universidad Nacional de Colombia. Leticia; ColombiaFil: Marciales-Caro, Lili Joana. Instituto Amazónico de Investigaciones. Imani. Universidad Nacional de Colombia. Leticia; ColombiaFil: Castro-Roa, Denise. Instituto Amazónico de Investigaciones. Imani. Universidad Nacional de Colombia. Leticia; ColombiaFil: Cano, María Gabriela. División Ficología. Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; ArgentinaFil: Calderón-Chérrez, María José. Universidad Central del Ecuador. Escuela de BiologíaFil: Echenique, Ricardo Omar. División Ficología. Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; Argentin

Peces del alto Magdalena, cuenca del río Magdalena, Colombia

-Artículo revisado por pare

Peces del alto Magdalena, cuenca del río Magdalena, Colombia

Peces del alto Magdalena, cuenca del río Magdalena, Colombi

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population