255 research outputs found
Development of a fatigue life prediction methodology for welded steel semi-trailer components based on a new criterion
This paper presents a procedure developed to predict the fatigue life in components made of steel, based on the mechanical properties of the base material and Thermally Affected Zones (TAZs) owing to welding. The fatigue life cycles of the studied components are obtained based on a certain survival probability provided by a Weibull distribution. This procedure is thought to be applied on semi-trailer components, and therefore it is proposed for the steels that are typically used in its manufacturing. A criterion for the adjustment of the exponent and the stress stroke of the fatigue life curve in welded joints is proposed in which the parameters that define the alternating stress versus the number of cycles to failure (S-N) curve are obtained exclusively from the ratio between the base material yield stress of a given steel and the strength of its Thermally Affected Zone. This procedure is especially useful for steels that do not have a complete characterization of their fatigue parameters. These developments are implemented in a subroutine that can be applied in commercial codes based on Finite Element Method (FEM) to obtain a fatigue life prediction. Finally, a numerical-experimental validation of the developed procedure is carried out by means of a semi-trailer axle bracing support fatigue analysis
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On the nonlinear hunting stability of a high-speed train bogie
The hunting phenomenon is an intrinsic swaying motion appearing in railway vehicles due to the vehicle’s forward speed and the wheel–rail contact forces. Hunting motion consists of wheelset and other vehicle’s components oscillations that arise above a certain vehicle’s speed known as critical or hunting speed. These oscillations are of unstable nature and represent a safety hazard as they could lead to the vehicle’s derailment. This article analyses the stability of a bogie nonlinear model for a Spanish high-speed train when this is travelling at speeds near the hunting speed. The vehicle’s stability is studied by means of root loci methods, and the value of the critical speed is found. In addition to this, the behaviour of the vehicle is studied in both stable and unstable regions and the existence of limit cycles is discussed in this work. Finally, a sensitivity analysis of the axle load and suspension parameters is performed. The results show that the axle load, the vertical stiffness of the primary suspension and the lateral damping of the secondary suspension have a significant influence on the value of the critical speed
Zinc depletion regulates the processing and secretion of IL-1β.
Sterile inflammation contributes to many common and serious human diseases. The pro-inflammatory cytokine interleukin-1β (IL-1β) drives sterile inflammatory responses and is thus a very attractive therapeutic target. Activation of IL-1β in sterile diseases commonly requires an intracellular multi-protein complex called the NLRP3 (NACHT, LRR, and PYD domains-containing protein 3) inflammasome. A number of disease-associated danger molecules are known to activate the NLRP3 inflammasome. We show here that depletion of zinc from macrophages, a paradigm for zinc deficiency, also activates the NLRP3 inflammasome and induces IL-1β secretion. Our data suggest that zinc depletion damages the integrity of lysosomes and that this event is important for NLRP3 activation. These data provide new mechanistic insight to how zinc deficiency contributes to inflammation and further unravel the mechanisms of NLRP3 inflammasome activation
Lie symmetries for equations in conformal geometries
We seek exact solutions to the Einstein field equations which arise when two
spacetime geometries are conformally related. Whilst this is a simple method to
generate new solutions to the field equations, very few such examples have been
found in practice. We use the method of Lie analysis of differential equations
to obtain new group invariant solutions to conformally related Petrov type D
spacetimes. Four cases arise depending on the nature of the Lie symmetry
generator. In three cases we are in a position to solve the master field
equation in terms of elementary functions. In the fourth case special solutions
in terms of Bessel functions are obtained. These solutions contain known models
as special cases.Comment: 19 pages, To appear in J. Phys.
Kinematic Self-Similarity
Self-similarity in general relativity is briefly reviewed and the differences
between self-similarity of the first kind and generalized self-similarity are
discussed. The covariant notion of a kinematic self-similarity in the context
of relativistic fluid mechanics is defined. Various mathematical and physical
properties of spacetimes admitting a kinematic self-similarity are discussed.
The governing equations for perfect fluid cosmological models are introduced
and a set of integrability conditions for the existence of a proper kinematic
self-similarity in these models is derived. Exact solutions of the irrotational
perfect fluid Einstein field equations admitting a kinematic self-similarity
are then sought in a number of special cases, and it is found that; (1) in the
geodesic case the 3-spaces orthogonal to the fluid velocity vector are
necessarily Ricci-flat and (ii) in the further specialisation to dust the
differential equation governing the expansion can be completely integrated and
the asymptotic properties of these solutions can be determined, (iii) the
solutions in the case of zero-expansion consist of a class of shear-free and
static models and a class of stiff perfect fluid (and non-static) models, and
(iv) solutions in which the kinematic self-similar vector is parallel to the
fluid velocity vector are necessarily Friedmann-Robertson-Walker (FRW) models.Comment: 29 pages, AmsTe
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