Integrand reduction of one-loop scattering amplitudes through Laurent series expansion

We present a semi-analytic method for the integrand reduction of one-loop amplitudes, based on the systematic application of the Laurent expansions to the integrand-decomposition. In the asymptotic limit, the coefficients of the master integrals are the solutions of a diagonal system of equations, properly corrected by counterterms whose parametric form is konwn a priori. The Laurent expansion of the integrand is implemented through polynomial division. The extension of the integrand-reduction to the case of numerators with rank larger than the number of propagators is discussed as well.Comment: v2: Published version: references and two appendices added. v3: Eq.(6.11) corrected, Appendix B updated accordingl

Efficiency improvements for the numerical computation of NLO corrections

In this paper we discuss techniques, which lead to a significant improvement of the efficiency of the Monte Carlo integration, when one-loop QCD amplitudes are calculated numerically with the help of the subtraction method and contour deformation. The techniques discussed are: holomorphic and non-holomorphic division into sub-channels, optimisation of the integration contour, improvement of the ultraviolet subtraction terms, importance sampling and antithetic variates in loop momentum space, recurrence relations.Comment: 34 pages, version to be publishe

NLO QCD corrections to off-shell top-antitop production with leptonic decays at hadron colliders

We present details of a calculation of the cross section for hadronic top-antitop production in next-to-leading order (NLO) QCD, including the decays of the top and antitop into bottom quarks and leptons. This calculation is based on matrix elements for \nu e e+ \mu- \bar{\nu}_{\mu}b\bar{b} production and includes all non-resonant diagrams, interferences, and off-shell effects of the top quarks. Such contributions are formally suppressed by the top-quark width and turn out to be small in the inclusive cross section. However, they can be strongly enhanced in exclusive observables that play an important role in Higgs and new-physics searches. Also non-resonant and off-shell effects due to the finite W-boson width are investigated in detail, but their impact is much smaller than naively expected. We also introduce a matching approach to improve NLO calculations involving intermediate unstable particles. Using a fixed QCD scale leads to perturbative instabilities in the high-energy tails of distributions, but an appropriate dynamical scale stabilises NLO predictions. Numerical results for the total cross section, several distributions, and asymmetries are presented for Tevatron and the LHC at 7 TeV, 8 TeV, and 14 TeV.Comment: 61 pp. Matches version published in JHEP; one more reference adde

NLO QCD+EW predictions for V + jets including off-shell vector-boson decays and multijet merging

We present next-to-leading order (NLO) predictions including QCD and electroweak (EW) corrections for the production and decay of off-shell electroweak vector bosons in association with up to two jets at the 13 TeV LHC. All possible dilepton final states with zero, one or two charged leptons that can arise from off-shell W and Z bosons or photons are considered. All predictions are obtained using the automated implementation of NLO QCD+EW corrections in the OpenLoops matrix-element generator combined with the Munich and Sherpa Monte Carlo frameworks. Electroweak corrections play an especially important role in the context of BSM searches, due to the presence of large EW Sudakov logarithms at the TeV scale. In this kinematic regime, important observables such as the jet transverse momentum or the total transverse energy are strongly sensitive to multijet emissions. As a result, fixed-order NLO QCD+EW predictions are plagued by huge QCD corrections and poor theoretical precision. To remedy this problem we present an approximate method that allows for a simple and reliable implementation of NLO EW corrections in the MePs@Nlo multijet merging framework. Using this general approach we present an inclusive simulation of vector-boson production in association with jets that guarantees NLO QCD+EW accuracy in all phase-space regions involving up to two resolved jets

Different Innate and Adaptive Immune Responses to SARS-CoV-2 Infection of Asymptomatic, Mild, and Severe Cases

SARS-CoV-2 is a novel coronavirus, not encountered before by humans. The wide spectrum of clinical expression of SARS-CoV-2 illness suggests that individual immune responses to SARS-CoV-2 play a crucial role in determining the clinical course after first infection. Immunological studies have focused on patients with moderate to severe disease, demonstrating excessive inflammation in tissues and organ damage. In order to understand the basis of the protective immune response in COVID-19, we performed a longitudinal follow-up, flow-cytometric and serological analysis of innate and adaptive immunity in 64 adults with a spectrum of clinical presentations: 28 healthy SARS-CoV-2-negative contacts of COVID-19 cases; 20 asymptomatic SARS-CoV-2-infected cases; eight patients with Mild COVID-19 disease and eight cases of Severe COVID-19 disease. Our data show that high frequency of NK cells and early and transient increase of specific IgA, IgM and, to a lower extent, IgG are associated with asymptomatic SARS-CoV-2 infection. By contrast, monocyte expansion and high and persistent levels of IgA and IgG, produced relatively late in the course of the infection, characterize severe disease. Modest increase of monocytes and different kinetics of antibodies are detected in mild COVID-19. The importance of innate NK cells and the short-lived antibody response of asymptomatic individuals and patients with mild disease suggest that only severe COVID-19 may result in protective memory established by the adaptive immune response

Scaling Patterns for QCD Jets

Jet emission at hadron colliders follows simple scaling patterns. Based on perturbative QCD we derive Poisson and staircase scaling for final state as well as initial state radiation. Parton density effects enhance staircase scaling at low multiplicities. We propose experimental tests of our theoretical findings in Z+jets and QCD gap jets production based on minor additions to current LHC analyses.Comment: 36 pages, 16 figure

Different Innate and Adaptive Immune Responses to SARS-CoV-2 Infection of Asymptomatic, Mild, and Severe Cases

SARS-CoV-2 is a novel coronavirus, not encountered before by humans. The wide spectrum of clinical expression of SARS-CoV-2 illness suggests that individual immune responses to SARS-CoV-2 play a crucial role in determining the clinical course after first infection. Immunological studies have focused on patients with moderate to severe disease, demonstrating excessive inflammation in tissues and organ damage. In order to understand the basis of the protective immune response in COVID-19, we performed a longitudinal follow-up, flow-cytometric and serological analysis of innate and adaptive immunity in 64 adults with a spectrum of clinical presentations: 28 healthy SARS-CoV-2-negative contacts of COVID-19 cases; 20 asymptomatic SARS-CoV-2-infected cases; eight patients with Mild COVID-19 disease and eight cases of Severe COVID-19 disease. Our data show that high frequency of NK cells and early and transient increase of specific IgA, IgM and, to a lower extent, IgG are associated with asymptomatic SARS-CoV-2 infection. By contrast, monocyte expansion and high and persistent levels of IgA and IgG, produced relatively late in the course of the infection, characterize severe disease. Modest increase of monocytes and different kinetics of antibodies are detected in mild COVID-19. The importance of innate NK cells and the short-lived antibody response of asymptomatic individuals and patients with mild disease suggest that only severe COVID-19 may result in protective memory established by the adaptive immune response