650 research outputs found

    PND30 Cost Analysis of Glatiramer Acetate Versus Fingolimod for the Treatment of Patients With Relapsing-Remitting Multiple Sclerosis in Spain

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    PMH16 Budgetary Impact Analysis of Buprenorphine/Naloxone (Suboxone®) in Opioid Maintenance Treatment in Spain

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    A Postprocessing methodology for direct normal irradiance forecasting using cloud information and aerosol load forecasts

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    A method for direct normal irradiance (DNI) forecasting for specific sites is proposed. It is based on the combination of a numerical weather prediction (NWP) model, which provides cloud information, with radiative transfer simulations fed with external aerosol forecasts. The NWP model used is the ECMWF Integrated Forecast System, and the radiative transfer information has been obtained from the Library of Radiative Transfer (libRadtran). Two types of aerosol forecasts have been tested: the global Monitoring Atmospheric Composition and Climate (MACC) model, which predicts five major components of aerosols, and the Dust Regional Atmospheric Model (BSC-DREAM8b) added to a fixed background calculated as the 20th percentile of the monthly mean of AERONET 2.0 observations from a different year. The methodology employed is valid for all meteorological situations, providing a stable and continuous DNI curve. The performance of the combined method has been evaluated against DNI observations and compared with the pure ECMWF forecasts at eight locations in the southern half of mainland Spain and the Canary Islands, which received high loadings of African dust for 2013 and 2014. Results for 1-day forecasts are presented. Although clouds play a major role, aerosols have a significant effect, but at shorter time scales. The combination of ECMWF and MACC forecasts gives the best global results, improving the DNI forecasts in events with high aerosol content. The regional BSC-DREAM8b yields good results for some extremely high dust conditions, although more reliable predictions, valid for any aerosol conditions, are provided by the MACC model

    Synthesis of Titanium and Zirconium Complexes with 2-Pyridonate and 2, 6-Pyridinedithiolate Ligands

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    Treatment of complex Cp2TiCl2] with the lithium salt of 2-hydroxypyridine afforded complex Cp2Ti(Opy)2] (1), whereas the same synthetic strategy applied to the analogous zirconium compound Cp2ZrCl2] did not worked. However, the use of the metallocene Cptt 2ZrMe2] with protic ligands allowed directing the reactivity towards protonation of the methyl groups attached to zirconium. To check this approach we reacted Cptt 2ZrMe2] with methanol affording complex Cptt 2ZrMe(OMe)] (2), which was characterized in situ by NMR techniques. In the same line, the reaction of Cptt 2ZrMe2] with 2-hydroxypyridine gave complex Cptt 2Zr(Me)(Opy)] (3)//forcing the conditions of this reaction did not lead to the expected complex Cptt 2Zr(Opy)2], most probably due to the steric hindrance exerted by the bulky cyclopentadienyl ligands. Further reactions of complex 3 with ligands having acidic protons also led to the recovery of the starting complex. However, when shifting to the bifunctional ligand 2, 6-dimercaptopyridine py(SH)2] a double protonation of the methyl ligands in Cptt 2ZrMe2] occurred, allowing the isolation of mononuclear complex Cptt 2Zr(¿S, ¿S, ¿N-pyS2)] (4), upon evolution of methane. The molecular structure of complex 4 was determined by X-ray methods, showing the zirconium atom in a highly distorted trigonal bipyramidal arrangement//structural parameters indicate a conventional Zr-N bond, but rather weak Zr-S interactions

    RTVE’s transmedia strategy aimed at young audiences: the case of Playz (2017-2020)

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    Generally speaking, audio-visual consumption is changing. More specifically, in recent years young people have increased their viewing of content through the Internet, which is often supplied through online platforms. This article focuses on one the Playz platform, which is one of the key strategies being used by Spanish public television (RTVE), as it aims to reconnect with the new generations through transmedia narratives. Based on studies undertaken by Costa Sánchez (2013) and Cascajosa-Virino (2018), a content analysis of the series broadcast on Playz between 2017 and 2020 has been carried out, taking into account the duration, year of release, and number of episodes or seasons for each of them. This study confirms a clear interest by this platform in generating products that are innovative from their very conception. In fact, a large number of transmedia strategies have been identified, such as episodes turned into films, a high degree of interactivity with the audience, original music videos, promotional events and more, which is in line with Playz’s public service obligation to reach out to all types of audiences through all the platforms available to them.El consumo audiovisual está cambiando de manera general y, en concreto, la juventud ha incrementado durante los últimos años el visionado de contenidos a través de Internet, a menudo servidos a través de plataformas online. Este artículo se centra en una de esas, Playz, una pieza estratégica de la televisión pública española (RTVE), en su objetivo de reconectar con las nuevas generaciones a través de narrativas transmedia. Partiendo de los estudios acometidos por Costa Sánchez (2013) y por Cascajosa-Virino (2018), se ha realizado un análisis del contenido de las series de Playz entre 2017 y 2020, y se han tenido en cuenta desde la temática, hasta la duración, pasando por el número de capítulos o de temporadas de cada una de ellas. Este trabajo muestra el claro interés de esta plataforma por generar productos innovadores desde su misma concepción. De hecho, se han identificado un gran número de estrategias transmedia (capítulos convertidos en películas, alto grado de interactividad con la audiencia, vídeos musicales originales, actos promocionales…), que siguen la línea de la obligación de servicio público de Playz de acercarse a toda clase de público y desde todas las plataformas puestas a su alcance

    Método rápido de obtención de aceite de oliva virgen para determinación de acidez

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    A rapid and simple method to obtain, from olive samples, enough quantity of oil to determine acidity grade is proposed. From paste samples of milled olives, different fraction are separated to be centrifugated during 5 minutes at 4500 r.p.m. Oil acidity results obtained from sodium sulfate anhidrous and natural microtalc added samples are compared with blank samples, and with those obtained by the Abencor extraction procedure. The correlation between the acidity of oil samples obtained by the Abencor method is also analyzed against other samples obtained by the normalized method in Spain, norm UNE 55070, Soxhlet system. Results show that in all the centrifugated samples enough amount of oil is obtained to determin the acidity grade, it also show that treatment with sodium sulfate anhidrous obtains a bigger recovery percentage, and that in all 3 cases, the acidity shows a good correlation with that of the Abencor system, doubling the number of samples analysed by the Abencor system. It also shows that the acidity grade obtained by using the UNE 55070 norm is aproximately 0,3 grades above that obtained by the Abencor system.<br><br>Se propone un método rápido y sencillo para obtener, a partir de muestras de aceitunas, suficiente cantidad de aceite para determinar su grado de acidez. A partir de muestras de pasta de aceitunas molidas se separan distintas fracciones que se someten a un proceso de centrifugación a 4500 r.p.m. durante 5 minutos. Se comparan los resultados de acidez de los aceites obtenidos de las muestras con adición de microtalco natural y sulfato sódico anhidro, con muestras testigo, así como con el procedimiento de extracción Abencor. Se analiza también la correlación entre la acidez de muestras de aceite obtenidas por el método Abencor, con otras obtenidas por el método normalizado en España, norma UNE 55070, basado en la extracción del aceite por el método Soxhlet. Los resultados ponen de manifiesto que en las muestras centrifugadas se obtiene cantidad suficiente de aceite para la determinación del grado de acidez, que el tratamiento con sulfato sódico anhidro consigue mayor porcentaje de recuperación, y que, en los tres casos, la acidez presenta buena correlación con la del sistema Abencor, duplicando el número de muestras analizadas respecto a este método. Así mismo, se demuestra que el valor de acidez obtenido al aplicar la norma UNE 55070 es aproximadamente 0,3 grados por encima del obtenido por el sistema Abencor

    References in communication policy research: a bibliographical characterization of articles published by Spanish authors

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    This paper provides a characterization of the bibliographicalreferences of Spanish scientific articles in the field ofcommunication policy using a bibliometric approach. Itanalyses 93 articles published by authors from Spanishinstitutions between 2002 and 2011 in major Spanish journalsincluded on the communication section of both the IN RECSindex and the Social Sciences Citation Index. The paperexamines the main references used by Spanish communicationpolicy researchers and the typology of these references, theirSpanish or international character and the most cited authorsin this field. The results show the disparity and adaptability ofarticles depending on the scope of the journals in which theyare published. Thus, articles published in international journalscontain more than twice as many references as those appearingin Spanish journals. The typology is also different; articles arethe most common source in international journals while bookspredominate in Spanish journals. These results are analyzed inthe context of the institutionalized practices of scientificproduction approved by university assessment agencies; theseare compared with the actual practices of researchers throughan analysis of the main bibliographical references
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