638 research outputs found

    The Federal Fisheries Service, 1871–1940: Its Origins, Organization, and Accomplishments

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    The U.S. Fish Commission was initiated in 1871 with Spencer Fullerton Baird as the first U.S. Fish Commissioner as an independent entity. In 1903 it became a part of the new U.S. Department of Commerce and Labor and was renamed the Bureau of Fisheries, a name it retained when the Departments of Commerce and Labor were separated in 1912. The Bureau remained in the Commerce Department until 1941 when it was merged with the Biological Survey and placed in the Department of Interior as the U.S. Fish and Wildlife Service. It was a scientific agency with well conceived programs of action, and it provided knowledge, advice, and example to state governments and individuals with fisheries interests and needs. Its efforts were supported by timely international agreements which constituted the precedent for Federal interest in fishery matters. The Fisheries Service earned stature as an advisor through heavy emphasis on basic biological research. The lack of such knowledge was marked and universal in the 1870’s, but toward the end of that decade, strong steps had been taken to address those needs under Baird’s leadership. USFC research activities were conducted cooperatively with other prominent scientists in the United States and abroad. Biological stations were established, and the world’s first and most productive deepsea research vessel, the Albatross, was constructed, and its 40-year career gave a strong stimulus to the science of oceanography. Together, the agency’s scientists and facilities made important additions to the sum of human knowledge, derived principles of conservation which were the vital bases for effective regulatory legislation, conducted extensive fish cultural work, collected and disseminated fisheries statistics, and began important research in methods of fish harvesting, preservation, transportation, and marketing

    Young Adult Literature: The State of a Restless Art

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    Speech on young adult literature by Michael Cart for the Ezra Jack Keats Lecture at the 2016 Fay B. Kaigler Children’s Book Festival (unedited)

    Presidential rhetoric in times of crisis: A textual analysis of speeches by franklin roosevelt and ronald reagan

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    While many scholars have examined the rhetoric of presidents Franklin Roosevelt and Ronald Reagan individually, there is a gap in literature concerning crisis rhetoric specifically and little has been done in the way of comparing these two men. This study is a textual analysis of six speeches given by Roosevelt and Reagan during times of crises. Because both presidents were important in defining an era and considered great communicators, this study compares the similarities and differences of their use of presidential crisis rhetoric. Previous research shows clear patterns in presidential rhetoric, including the common use of civil religious words and symbols, collective focus and imagery. This study analyzes Roosevelt\u27s and Reagan\u27s speeches for the use of predefined and common rhetorical devices in times of crisis. In the six speeches studied, the analysis indicated that each president regularly used the uplifting of democracy and civil religion when addressing the nation in times of crisis. Also, the research suggests that the presidents\u27 differing political affiliations influenced the way they spoke about the use of the Constitution and their executive power in order to address crises. Thus, Roosevelt and Reagan\u27s use of the pre-defined rhetorical terms listed in this study and the use of political party-specific rhetoric concerning the power of the executive branch may have influenced the effectiveness of their overall crisis rhetoric in regard to United States\u27 citizens and may offer a broader understanding and interpretation of the contemporary political world

    Continuing Continuing the Conversation

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    The Role of Notch1 and Notch3 in Adult Stem Cell Osteogenic Differentiation

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    Human adipose-derived stem cells (hASCs) have significant therapeutic potential due to their ability to self-renew, differentiate down multiple lineages, and modulate the immune system. In addition to these many benefits, hASCs boast a minimally invasive harvesting procedure, making them a readily available cell source for stem cell research and tissue regeneration (Ock, et al. 2016) (Abdi, et al. 2008). Despite their broad use, very little is known about the mechanisms that control cell fate. One way to enhance our mechanistic understanding of differentiation is through the systematic examination of the signaling pathways. The Notch signaling pathway is a highly conserved, contact dependent, cell-to-cell signaling cascade known to regulate cell state and multipotent differentiation of hASCs. This pathway consists of four unique receptors and five unique ligands (Braune and Lendahl 2016). Two receptors believed to play a significant role in regulating osteogenic differentiation are Notch1 and Notch3. Here the expression of Notch1 and Notch3 are characterized during osteogenesis and the effect that siRNA-mediated knockdown of each receptor has on osteogenic differentiation is evaluated. By studying changes in osteogenic marker expression following a reduction in Notch expression and activity, we will be able to determine how each receptor individually affects the osteogenic potential of hASCs and identify potential novel therapeutic targets to treat bone damage and loss

    Social and economic theories of John Ruskin ..

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    Typewritten sheets in cover. Thesis (M.A.)--Boston University This item was digitized by the Internet Archive. Bibliography, 2 p

    Automatisation du traitement des documents CERN

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    Within the context of producing the List of CERN Publications, the library is aiming to replace the manual analysis of periodicals and conference proceedings by automatic procedures. These rely on importing references of publication or bibliographic notices and by querying databases

    03. Notch Signaling Plays a Key Role in Regulating Adult Stem Cell Osteogenic Differentiation

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    Human adipose-derived stem cells (hASCs) are an easily accessible type of multipotent stem cell that boasts immense potential as a cell source for personalized regenerative medicine. Given their tremendous clinical potential, our research strives to better understand hASCs and their potential use in combating degenerative bone diseases such as osteoporosis and trauma related degradation. We are specifically interested in deciphering the role of the highly conserved Notch signaling pathway and how it might be manipulated to enhance bone differentiation and regeneration. The Notch signaling pathway is a cell-to-cell contact dependent pathway that is involved in cellular homeostasis, stem cell differentiation, and cell fate determination. Notch1 and Notch3 are two receptors in the Notch signaling pathway that play a critical role in osteogenesis and self-renewal. To better understand the role of these two receptors, siRNA knockdowns are performed. Small interfering RNAs lead to the degradation of a significant amount of a targeted mRNA transcript, and in turn results in a significant decrease in protein expression. The literature indicates that a decrease in Notch1 expression leads to a decrease in osteogenic differentiation. Given data in the literature for other types of cells, we expect to confirm that the decrease in Notch1 leads to a decrease in hASC osteogenesis while the decrease in Notch3 may lead to enhanced differentiation. Identifying the role of each receptor will aid in identifying potential therapeutic targets for treating bone degeneration and loss in the future

    Determining Expression Levels of the Notch Signaling Pathway in Self-Renewing hASCs

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    The abstract for this presentation can be downloaded by clicking on the blue download button
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