Emprendimiento peruano en el marco del desarrollo sostenible

in the Peruvian context, entrepreneurship has become a determining factor in driving the country’s social and economic progress. In addition, it plays an active role in the achievement of the Sustainable Development Goals proposed by the United Nations. The main objective of the study was to establish the relationship between Peruvian entrepreneurship and sustainable development. A quantitative, non-experimental, correlational and cross-sectional approach was used the study population was established using data from the technical report EntrepreneurialDemographics of Peru, according to this report, 2,054 ventures were registered and established in the year 2021, with a life cycle of two years atthe time of the study. For the sample, 746 ventures were purposively selected. A questionnaire composed of 40 items with Likert-type responseoptions was used, was validated by five experts and its reliability was established through the Cronbach’s Alpha measure, obtaining a very reliablecoefficient of 0.93. The resulting data were analyzed using the SPSS version 25 statistical software. The results revealed a moderate positivecorrelation between entrepreneurship in Peru and sustainable development. In conclusion, entrepreneurship in Peru is significantly related tosustainable development, especially in terms of contributing to the SDGs and promoting innovation and adaptability. However, greater attentionto community engagement is required to strengthen the relationship between entrepreneurship and the broader community.en el contexto peruano, el emprendimiento se ha consolidado como un factor determinante para impulsar el progreso social y económico del país. Además, desempeña un papel activo en la consecución de los Objetivos de Desarrollo Sostenible propuestos por las Naciones Unidas. El objetivo central del estudio fue establecer la relación entre el emprendimiento peruano y el desarrollo sostenible. Se utilizó un enfoque cuantitativo, no experimental, correlacional y transversal. La población de estudio se estableció utilizando datos del informe técnico Demografía Empresarial del Perú, según este informe, se registraron y establecieron 2054 emprendimientos en el año 2021, con un ciclo de vida de dos años en el momento del estudio. Para la muestra se seleccionaron intencionalmente 746 emprendimientos. Se utilizó un cuestionario compuesto por 40 ítems con opciones de respuesta tipo Likert, fue validado por cinco expertos y se estableció su confiabilidad a través de la medida Alfa de Cronbach, obteniendo un coeficiente muy confiable de 0.93. Los datos resultantes fueron analizados utilizando el programa estadístico SPSS versión 25. Los resultados revelaron una correlación positiva moderada entre el emprendimiento en Perú y el desarrollo sostenible. En conclusión, el emprendimiento en Perú está relacionado de manera significativa con el desarrollo sostenible, especialmente en términos de contribución a los ODS y la promoción de la innovación y adaptabilidad. Sin embargo, se requiere una mayor atención a la participación comunitaria para fortalecer la relación entre el emprendimiento y la comunidad en general

Emprendimiento peruano en el marco del desarrollo sostenible

En el contexto peruano, el emprendimiento se ha consolidado como un factor determinante para impulsar el progreso social y económico del país. Además, desempeña un papel activo en la consecución de los Objetivos de Desarrollo Sostenible propuestos por las Naciones Unidas. El objetivo central del estudio fue establecer la relación entre el emprendimiento peruano y el desarrollo sostenible. Se utilizó un enfoque cuantitativo, no experimental, correlacional y transversal. La población de estudio se estableció utilizando datos del informe técnico Demografía Empresarial del Perú, según este informe, se registraron y establecieron 2054 emprendimientos en el año 2021, con un ciclo de vida de dos años en el momento del estudio. Para la muestra se seleccionaron intencionalmente 746 emprendimientos. Se utilizó un cuestionario compuesto por 40 ítems con opciones de respuesta tipo Likert, fue validado por cinco expertos y se estableció su confiabilidad a través de la medida Alfa de Cronbach, obteniendo un coeficiente muy confiable de 0.93. Los datos resultantes fueron analizados utilizando el programa estadístico SPSS versión 25. Los resultados revelaron una correlación positiva moderada entre el emprendimiento en Perú y el desarrollo sostenible. En conclusión, el emprendimiento en Perú está relacionado de manera significativa con el desarrollo sostenible, especialmente en términos de contribución a los ODS y la promoción de la innovación y adaptabilidad. Sin embargo, se requiere una mayor atención a la participación comunitaria para fortalecer la relación entre el emprendimiento y la comunidad en general.//In the Peruvian context, entrepreneurship has become a determining factor in driving the country’s social and economic progress. In addition, it plays an active role in the achievement of the Sustainable Development Goals proposed by the United Nations. The main objective of the study was to establish the relationship between Peruvian entrepreneurship and sustainable development. A quantitative, non-experimental, correlational and cross-sectional approach was used the study population was established using data from the technical report Entrepreneurial Demographics of Peru, according to this report, 2,054 ventures were registered and established in the year 2021, with a life cycle of two years at the time of the study. For the sample, 746 ventures were purposively selected. A questionnaire composed of 40 items with Likert-type response options was used, was validated by five experts and its reliability was established through the Cronbach’s Alpha measure, obtaining a very reliable coefficient of 0.93. The resulting data were analyzed using the SPSS version 25 statistical software. The results revealed a moderate positive correlation between entrepreneurship in Peru and sustainable development. In conclusion, entrepreneurship in Peru is significantly related to sustainable development, especially in terms of contributing to the SDGs and promoting innovation and adaptability. However, greater attention to community engagement is required to strengthen the relationship between entrepreneurship and the broader community

Synthesis of ZnO nanoparticles by flame spray pyrolysis and characterisation protocol

There is uncertainty concerning the potential toxicity of zinc oxide (ZnO) nanoparticles, which may be attributed in part to a lack of understanding with regard to the physiochemical properties of the nanoparticles used in toxicological investigations. This paper reports the synthesis of a ZnO nanopowder by flame spray pyrolysis and demonstrates that the typically employed characterisation techniques such as specific surface area measurement and X-ray diffraction provide insufficient information on the sample, especially if it is intended for use in toxicity studies. Instead, a more elaborate characterisation protocol is proposed that includes particle morphology as well as detailed compositional analysis of the nanoparticle surface. Detailed transmission electron microscopy analysis illustrated the polydispersity within the sample: particles were elongated in the c-crystallographic direction, with average Ferret length ∼23 nm and Ferret width ∼14 nm. Dynamic light scattering (0.1 w/v% in deionised water, pH 7.4) revealed the particles were agglomerated with a modal secondary particle size of ∼1.5 μm. Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy indicated the presence of carbonate and hydroxide impurities on the surface of the ZnO nanoparticles and an increase of such impurities was observed as the sample was aged, which might influence the nanoparticle dissolution and/or cellular uptake behaviour. These data will be utilised, in order to facilitate the interpretation and understanding of results from toxicological investigations using in vitro cell lines

From trivial to severe arrhythmias: the diagnostic role of multimodality imaging in inflammatory cardiomyopathy through a case series.

The diagnosis of inflammatory cardiomyopathy remains challenging in cases presenting with arrhythmia as sole manifestation. An early diagnosis is critical as it may prevent life-threatening complications such as sudden cardiac death and atrioventricular block (AVB). The diagnostic workup of suspected cases includes multimodality imaging that requires an adequate interpretation in order to limit the risk of overdiagnosis. Herein, we report three cases presenting with various new-onset arrhythmias. The first patient was admitted for a third-degree AVB. The second patient suffered from a supraventricular tachycardia which degenerated into ventricular fibrillation. The third case was investigated for symptomatic premature ventricular complexes. No apparent heart disease was observed on standard exams (clinical, biological examinations, and echocardiography). However, cardiac magnetic resonance imaging (MRI) and nuclear imaging ( <sup>68</sup> Ga-DOTATOC and/or <sup>18</sup> F-FDG PET/CT) suggested an inflammatory substrate that seemed to correlate with the arrhythmic phenotype. Cardiac inflammation disappeared on immunotherapy for the first case and spontaneously for the third case. These cases emphasize the incremental diagnostic yield of multimodality imaging to highlight myocardial inflammation. Nuclear imaging modalities may complement MRI by enabling the detection of active inflammation. The <sup>18</sup> F-FDG PET/CT is well established for the diagnosis of cardiac sarcoidosis but its role remains to be clarified for the diagnosis of myocarditis. An alternative radiotracer, <sup>68</sup> Ga-DOTATOC, appears promising by overcoming the main limitation of <sup>18</sup> F-FDG but its specificity is not yet well established. The role of functional investigations is discussed as well as the benefit of immunosuppressive treatments

Education in values and resilience from a multidisciplinary perspective

La presente investigación está dirigida a analizar la correspondencia entre educación en valores y resiliencia, desde una perspectiva multidisciplinaria, desarrollándola en la Universidad del Zulia, Maracaibo, Venezuela. Metodológicamente se enmarcó en el enfoque cualitativo con paradigma interpretativo de tipo fenomenológico. La técnica fue la entrevista semiestructurada aplicada a 20 profesionales de distintas disciplinas (médicos, abogados, psicólogos, enfermeros/as, ingenieros, arquitectos, licenciados en educación, trabajadores/as sociales, contador, economista), quienes respondieron a las preguntas resaltando con la interpretación, la presencia de categorías emergentes tales como: antivalores, código de ética, tarea de todos, formación integral, modelo, resiliencia. Se concluye con el aporte de los diferentes profesionales de áreas científicas y humanísticas que educar en valores es un trabajo de todos y se requiere ser resiliente cuando las personas conozcan lo que quieren, insistan y persistan en su acción para lograrlo, por el bien individual y colectivo, de allí la correspondencia entre las categorías estudiadas.This research aims at investigating analyzing the correspondence between education in values and resilience, from a multidisciplinary perspective, developing it at the University of Zulia, Maracaibo, Venezuela. Methodologically, is the qualitative approach with an interpretative paradigm of a phenomenological type.  The technique was the semi-structured interview applied to 20 professionals from different disciplines (doctors, lawyers, psychologists, nurses, engineers, architects, graduates in education, social worker, accountant, economist), who answered the questions highlighting with interpretation, the presence of emerging categories such as: anti-values, code of ethics, everyone's task, integral training, model, resilience. It concludes with the contribution of the different professionals of scientific and humanistic areas that educating in values is a work of all and it is required to be resilient, that people know what they want, insist and persist in their action to achieve it, for the individual and collective good, hence the correspondence between the categories studied.&nbsp

New Insights in Central Venous Disorders. The Role of Transvenous Lead Extractions.

Over the last decades, the implementation of new technology in cardiac pacemakers and defibrillators as well as the increasing life expectancy have been associated with a higher incidence of transvenous lead complications over time. Variable degrees of venous stenosis at the level of the subclavian vein, the innominate trunk and the superior vena cava are reported in up to 50% of implanted patients. Importantly, the number of implanted leads seems to be the main risk factor for such complications. Extraction of abandoned or dysfunctional leads is a potential solution to overcome venous stenosis in case of device upgrades requiring additional leads, but also, in addition to venous angioplasty and stenting, to reduce symptoms related to the venous stenosis itself, i.e., the superior vena cava syndrome. This review explores the role of transvenous lead extraction procedures as therapeutical option in case of central venous disorders related to transvenous cardiac leads. We also describe the different extraction techniques available and other clinical indications for lead extractions such as lead infections. Finally, we discuss the alternative therapeutic options for cardiac stimulation or defibrillation in case of chronic venous occlusions that preclude the implant of conventional transvenous cardiac devices

Práctica de valores. Una perspectiva de mediación del trabajador social ante los conflictos en las relaciones humanas.

The Social Worker is a professional focused on the social needs of people, groups and communities that interact in a society, which implies that his mediating action is characterized by the practice of moral and social values ??that allow him to reach people at the intervene in the conflicts that can arise in their human relationships, hence this article is developed with the purpose of analyzing the practice of values ??as a mediation perspective of the Social Worker in the face of conflicts in relationships between individuals. This research was directed under a descriptive, documentary, bibliographic methodological position, with content analysis in relation to studies carried out on the subject. In the results it was evidenced that the mediating actions carried out by the social professional are characterized by respect, solidarity, justice, equal opportunities, among others, to establish mutual agreements, in such a way that human relations do not present fainting, being the duty to be rather, that the communicative interactions between the social subjects are strengthened.El Trabajador Social, es un profesional enfocado en las necesidades sociales de las personas, grupos y comunidades que interactúan en una sociedad, lo cual implica que su acción mediadora esté caracterizada por la práctica de valores morales y sociales que le permitan llegar a la gente al intervenir en los conflictos que se pueden presentar en sus relaciones humanas, de allí que se desarrolla este artículo con el propósito de analizar la práctica de valores como perspectiva de mediación del Trabajador Social ante los conflictos en las relaciones entre los individuos. Esta investigación se direccionó bajo una postura metodológica descriptiva, documental, bibliográfica, con análisis de contenido en relación a estudios realizados sobre la temática. En los resultados se evidenció que, las acciones mediadoras ejecutadas por el profesional de lo social, están caracterizadas por el respeto, la solidaridad, justicia, igual de oportunidades, entre otras, para establecer mutuos acuerdos, de tal forma que, las relaciones humanas no presenten desvanecimientos, siendo el deber ser más bien, que se fortalezcan las interacciones comunicativas entre los sujetos sociales

Tissu adipeux épicardique et fibrillation auriculaire [Epicardial adipose tissue and atrial fibrillation]

Atrial fibrillation (AF) is the most common arrhythmia encountered in adults; it is associated with a significant morbidity and mortality. Obesity is a risk factor contributing to AF occurrence. Recently, interest has focused on epicardial adipose tissue (EAT), defined as a fatty deposit located between the epicardium and the visceral pericardium. Its characteristics are distinct from classic adipose deposits: it infiltrates the epicardial myocardium and secretes cytokines, which modulate cardiomyocyte electrophysiology and cardiac remodeling. Different studies show that EAT can be an independent risk factor for AF and that EAT thickness, as measured by CT or MRI, could predict the presence, severity and recurrence of AF

Leadless pacing using the transcatheter pacing system (Micra TPS) in the real world: initial Swiss experience from the Romandie region.

Leadless pacemakers are implanted in Switzerland since June 2015. Large worldwide registries have shown high implant success, low complication rates, and good electrical parameters up to 12 months' follow-up. However, data are scarce outside the investigational setting. The purpose of this study is to assess the real-world experience regarding clinical safety and efficacy of Micra TPS (transcatheter pacing system) leadless pacemakers. Retrospective observational, multi-centre study designed to assess initial safety and efficacy of the Micra TPS in the Swiss Romande region. A total of 92 patients were included from four different centres with an implantation success rate of 97.8% (90 of 92). Thresholds were overall low at implantation (median 0.38 V/0.24 ms, ranging from 0.13 to 2.88 V/0.24 ms) and remained stable over 1-year follow-up. The perioperative serious adverse event rate was 6.5% in six patients which lead to prolonged hospitalization in five patients and death in one patient. In addition, three further major events (3.3%) occurred during an average follow-up of 1 year, requiring implantation of a standard transvenous pacemaker in two patients, and surgical explantation of the Micra TPS in one patient due to intractable ventricular tachycardia. Leadless pacemakers are a valuable adjunct for treating selected patients requiring single-chamber pacing. However, in this initial experience, major complication rates were high (9.8%). The implant procedure requires proper training and should be performed in an adequate setting