Spatially variable rate herbicide application on durum wheat in Sicily

Using the conventional farming system, durum wheat requires high rates of herbicide spraying. Herbicide residues can cause pollution of soil and ground water and, therefore, of the entire environment. In order to minimise the environmental impact of herbicides, a home made system for spatially variable rate crop input application was designed, developed and set up by the Department of Engineering and Technologies in Agriculture and Forestry (I.T.A.F.). This system consists of a DGPS, a portable computer, a specifically developed software and a device for applying rates proportionally related to the machine forward speed (DPA). Tests of spatially variable rate herbicide application were carried out in inland Sicily, on a field of 8.4 ha (where a three-year crop rotation, broad bean/vetch - durum wheat - durum wheat, was practised), using a sprayer modified for applying variable rates and equipped with the above mentioned system. The results are promising. The spatially variable rate herbicide application allowed an almost even grain yield over the entire field and a saving of 29% of herbicides with respect to the amounts normally used with the conventional farming system

Data-driven fracture mechanics

We present a new data-driven paradigm for variational brittle fracture mechanics. The fracture-related material modeling assumptions are removed and the governing equations stemming from variational principles are combined with a set of discrete data points, leading to a model-free data-driven method of solution. The solution at a given load step is identified as the point within the data set that best satisfies either the Kuhn–Tucker conditions stemming from the variational fracture problem or global minimization of a suitable energy functional, leading to data-driven counterparts of both the local and the global minimization approaches of variational fracture mechanics. Both formulations are tested on different test configurations with and without noise and for Griffith and R-curve type fracture behavior

Impact of mapping errors on the reliability of landslide hazard maps

International audienceIdentification and mapping of landslide deposits are an intrinsically difficult and subjective operation that requires a great effort to minimise the inherent uncertainty. For the Staffora Basin, which extends for almost 300 km2 in the northern Apennines, three landslide inventory maps were independently produced by three groups of geomorphologists. In comparing each map with the others, large positional discrepancies arise (in the range of 55?65%). When all three maps are overlain, the locational mismatch of landslide deposit polygons increases to over 80%. To assess the impact of these errors on predictive models of landslide hazard, for the study area discriminant models were built up from the same set of geological-geomorphological factors as predictors, and the occurrence of landslide deposits within each terrain-unit, derived from each inventory map, as dependent variable. The comparison of these models demonstrates that statistical modelling greatly minimises the impact of input data errors which remain, however, a major limitation on the reliability of landslide hazard maps

Long term outcome and EuroSCORE II validation in native valve surgery for active infective endocarditis in a South African cohort

Objectives: To evaluate the major risk factors for adverse short and long term outcomes in patients with active native valve infective endocarditis needing cardiac surgery and to validate the EuroSCORE II in our cohort of patients.Methods: We retrospectively studied 149 patients who underwent native valve surgery for infective endocarditis in June 2000 - May 2011 at our referral centre. Ninety-six patients met the inclusion criteria for the study: 29 aortic valve replacements (AVR), 27 mitral valve replacements (MVR), 28 aortic/mitral (double) valve replacements (DVR) and 12 mitral valve repairs (MV Repair).Results: Mechanical valves were implanted in 68 patients (70.8%), bioprosthetic valves in 16 (16.7%) and mitral annuloplasty rings in 12 (12.5%). The Cox proportional hazard model showed that the most important risk factors for early 30-day mortality were: critical preoperative state, emergency surgery, EuroSCORE II >12%, low cardiac output state (LCOS), HIV positive status, preoperative embolic episodes, vegetation size >1cm and postoperative ventilation >24 hours. The EuroSCORE II underestimated early mortality for the entire cohort. The discriminatory ability was evaluated with the receiver operating characteristic (ROC) curve with an area under the curve of 0.796. The discriminatory ability in the subgroup analysis showed that the AUROC curve was poorer for MVR (0.696), 0.837 for DVR and better for AVR group (0.92).Conclusions: The EuroSCORE II underestimated mortality in the highest risk groups and overestimated mortality in the lowest risk groups. The discriminatory ability and model fit were evaluated to be good and a EuroSCORE II >12% predicted a signifi cantly higher early and medium term mortality

Euler-Bessel and Euler-Fourier Transforms

We consider a topological integral transform of Bessel (concentric isospectral sets) type and Fourier (hyperplane isospectral sets) type, using the Euler characteristic as a measure. These transforms convert constructible \zed-valued functions to continuous $\real$-valued functions over a vector space. Core contributions include: the definition of the topological Bessel transform; a relationship in terms of the logarithmic blowup of the topological Fourier transform; and a novel Morse index formula for the transforms. We then apply the theory to problems of target reconstruction from enumerative sensor data, including localization and shape discrimination. This last application utilizes an extension of spatially variant apodization (SVA) to mitigate sidelobe phenomena

Precision oncology by point-of-care therapeutic drug monitoring and dosage adjustment of conventional cytotoxic chemotherapies: A perspective.

Therapeutic drug monitoring (TDM) of conventional cytotoxic chemotherapies is strongly supported yet poorly implemented in daily practice in hospitals. Analytical methods for the quantification of cytotoxic drugs are instead widely presented in the scientific literature, while the use of these therapeutics is expected to keep going for longer. There are two main issues hindering the implementation of TDM: turnaround time, which is incompatible with the dosage profiles of these drugs, and exposure surrogate marker, namely total area under the curve (AUC). Therefore, this perspective article aims to define the adjustment needed from current to efficient TDM practice for cytotoxics, namely point-of-care (POC) TDM. For real-time dose adjustment, which is required for chemotherapies, such POC TDM is only achievable with analytical methods that match the sensitivity and selectivity of current methods, such as chromatography, as well as model-informed precision dosing platforms to assist the oncologist with dose fine-tuning based on quantification results and targeted intervals

An Innovative System for Vineyard Management in Sicily

The aim of this study was to monitor the micro-climate of the grapevine in order to detect the adversities of the spring period (especially April and May), while reducing the operating costs of the vineyard, and increasing the overall quality of grapes. For this purpose a Wireless Sensor Network (WSN) was used. Furthermore, a comparison was performed between data measured by the wireless sensors and data provided by the fixed meteorological station of the Regione Siciliana (SIAS)

Qualitative and quantitative photogrammetric techniques for multi-temporal landslide analysis

The results of two survey methods, geological photointerpretation and historical photogrammetry, are compared in order to evaluate the temporal evolution of a unstable slope located in the Tuscan-Emilian Apennines (Italy). Historical aerial photos of the area, derived from photogrammetric surveys conducted in 1954 (scale 1:60000), in 1971 (scale 1:20000), and in 1976 (scale 1:17000) were available. A photogrammetric flight was further conducted in 2000, at a scale of 1:4400, with a traditional GPS ground survey support. First, the results of photographic analysis with the photointerpretation method are presented: the landslides are described from a geological point of view, showing its temporal evolution. To quantitatively assess the landslide movements, Digital Terrain Models were generated by means of an analytical plotter and a digital photogrammetric workstation, with semi-automatic and automatic procedures. To generate these products, it was necessary to solve problems related to a lack of data concerning the aerial cameras used for the historical flights (internal orientation) and the difficulty identifying control points on the photos in order to define the external orientation. An unconventional photogrammetric methodology, based on identification of homologous points in zones considered outside the landslide area, has been there developed and tested to insert the various surveys into a single reference system

DORIS_Net: enhancing the regional impact of COPERNICUS program by setting up the European Network of Regional Contact Offices

Despite successful technological developments, COPERNICUS, the European Earth Observation flagship program, has been showing a weak regional involvement with regards to the wide capacities and benefits it provides for the Environment and Security domains at public and private level. During the project, a methodology was successfully implemented to raise regional awareness on COPERNICUS potential with the concept of a Regional Contact Offices (RCO) Network. This paper aims to describe the process of RCO's creation and certification. It also presents both benefits and challenges of management and sustainability faced by RCO in order to reach their operational goals. Finally, the paper explores the potential regional impact of RCO