Reestruturação da gestão de uma empresa revendedora de produtos para serigrafia, estamparia e similares em Criciúma – SC

Artigo submetido ao Curso de Administração da Universidade do Extremo Sul Catarinense para obtenção do Grau de Bacharel em Administração.O objetivo do estudo foi analisar a reestruturação financeira de uma empresa revendedora de produtos para serigrafia, estamparia e similares a fim de estudar o planejamento estratégico, tático e operacional da empresa vendo os pontos que necessitam de mudanças. Como na empresa se faz necessário à reestruturação geral em todos os parâmetros administrativos como no setor da controladoria, tesouraria, dos níveis de planejamentos e financeiro, dos fluxos de caixa entre outros. Com isso os assuntos abordados foram o faturamento, crescimento da empresa, aumento dos colaboradores, abertura de contas bancárias, aumento e corte de clientes, são os principais fatores que a empresa mais precisava de atenção no momento em questão. A empresa em estudo era gerenciada pelo dono, para que acontecesse a reestruturação da empresa foi contratado um administrador para assumir toda a parte de gestão da empresa, agora o dono está focado na área de vendas aumentando ainda mais o faturamento da empresa. Cada ano que passa o mundo está cada vez mais globalizado, todos interligados diretamente uns com os outros, as empresas necessitam de profissionais nos quais sejam capacitados para auxiliar ainda mais o crescimento das empresas

Parametric Resonance in Electrostatically Actuated Micromirrors

We consider an electrostatically actuated torsional micromirror, a key element of recent optical microdevices. The mechanical response is analyzed with specific emphasis on its nonlinear features. We show that the mirror motion is an example of parametric resonance, activated when the drive frequency is twice the natural frequency of the system. The numerical model, solved with a continuation approach, is validated with very good accuracy through an extensive experimental campaign

BankSealer: An Online Banking Fraud Analysis and Decision Support System

Part 9: Malicious Behavior and FraudInternational audienceWe propose a semi-supervised online banking fraud analysis and decision support approach. During a training phase, it builds a profile for each customer based on past transactions. At runtime, it supports the analyst by ranking unforeseen transactions that deviate from the learned profiles. It uses methods whose output has a immediate statistical meaning that provide the analyst with an easy-to-understand model of each customer’s spending habits. First, we quantify the anomaly of each transaction with respect to the customer historical profile. Second, we find global clusters of customers with similar spending habits. Third, we use a temporal threshold system that measures the anomaly of the current spending pattern of each customer, with respect to his or her past spending behavior. As a result, we mitigate the undertraining due to the lack of historical data for building of well-trained profiles (of fresh users), and the users that change their (spending) habits over time. Our evaluation on real-world data shows that our approach correctly ranks complex frauds as “top priority”

Right ventricular endocardial segmentation in CMR images using a novel inter-modality statistical shape modelling approach

Statistical shape modelling (SSM) approaches have been proposed as a powerful tool to segment the left ventricle in cardiac magnetic resonance (CMR) images. Our aim was to extend this method to segment the RV cavity in CMR images and validate it compared to the conventional gold-standard (GS) manual tracing. A SSM of the RV was built using a database of 4347 intrinsically 3D surfaces, extracted from transthoracic 3D echo cardiographic (3DE) images of 219 retrospective patients. The SSM was then scaled and deformed on the base of some features extracted, with different strategies, from each short-axis plane until a stable condition was reached. The proposed approach, tested on 14 patients, resulted in a high correlation (r2=0.97) and narrow limits of agreement (± 17% error) when comparing the semiautomatic volumes to the GS, confirming the accuracy of this approach in segmenting the RV endocardium

Evaluation of different statistical shape models for segmentation of the left ventricular endocardium from magnetic resonance images

International audienceStatistical shape models (SSMs) represent a powerful tool used in patient-specific modeling to segment medical images because they incorporate a-priori knowledge that guide the model during deformation. Our aim was to evaluate segmentation accuracy in terms of left ventricular (LV) volumes obtained using four different SSMs versus manual gold standard tracing on cardiac magnetic resonance (CMR) images. A database of 3D echocardiographic (3DE) LV surfaces obtained in 435 patients was used to generate four different SSMs, based on cardiac phase selection. Each model was scaled and deformed to detect LV endocardial contours in the enddiastolic (ED) and end-systolic (ES) frames of a CMR short-axis (SAX) stack for 15 patients with normal LV function. Linear correlation and Bland–Altman analyses versus gold-standard showed in all cases high correlation (r²>0.95), non-significant biases and narrow limits of agreement

Descoberta de Conhecimento para Identificação de Fatores que Influenciam o Desempenho Discente

A identificação de possíveis perfis de desempenho acadêmico, logo nas primeiras fases do curso de graduação, pode ser um conhecimento útil para gestores de uma IES. Conhecendo os fatores que contribuem para um baixo desempenho acadêmico, ações podem ser tomadas para melhorar o desempenho acadêmico ou, em alguns casos, até prevenir uma evasão indesejada. Neste artigo, vários algoritmos de mineração de dados são aplicados em bases de dados de sistemas acadêmico e financeiro de alunos egressos dos cursos de Direito e Engenharia Civil, buscando identificar padrões de desempenho acadêmico e os fatores associados. Os cursos foram selecionados por serem de diferentes áreas e por terem maior número de egressos na IES estudada. Resultados obtidos apontam para evidências interessantes sobre o impacto de alguns atributos no desempenho acadêmico, tais como: tipo de disciplina, tipo de ingresso, uso do AVA e biblioteca; além das notas e frequência nas primeiras fases

Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases

Background: Immunohistochemistry (IHC) and fluorescent-in situ hybridization (FISH) are standard methods to assess human epidermal growth factor receptor 2 (HER2) status in breast cancer (BC) patients. Real-time quantitative polymerase-chain-reaction (qRT-PCR) is able to detect HER2 overexpression. Here we compared FISH, IHC, quantitative PCR (qPCR), and qRT-PCR to determine the concordance rates and evaluate their relative roles in HER2 determination. Patients and methods: We determined HER2 status in 153 BC patients, using IHC, FISH, Q-PCR and qRT-PCR. In discordant cases, we directly measured HER2 protein levels using Western blotting. Results: The overall agreement (OA) between FISH and Q-PCR was 94.1, with a k value of 0.87. Assuming FISH as the standard reference, Q-PCR showed an 86.1% sensitivity and a 99.0% specificity with a global accuracy of 91.6%. OA between FISH and qRT-PCR was 90.8% with a k value of 0.81. Of interest, the disagreement between FISH and qRT-PCR was mostly restricted to equivocal cases. HER2 protein analysis suggested that qRT-PCR correlates better than FISH with HER2 protein levels, particularly where FISH fails to provide conclusive results. Significance: qRT-PCR may outperform FISH in identifying patients overexpressing HER2 protein. Q-PCR cannot be used for HER2 status assessment, due to its suboptimal level of agreement with FISH. Both FISH and Q-PCR may be less accurate than qRT-PCR as surrogates of HER2 protein determination

Reconhecimento de antígenos por anticorpos de caprinos naturalmente infectados ou imunizados contra Corynebacterium pseudotuberculosis

Corynebacterium pseudotuberculosis is a gram positive bacillus, facultative intracellular pathogen of macrophages which is phylogenetically related with Mycobacterium tuberculosis. This pathogen is widely distributed in some animal species and is responsible for caseous lymphadenitis in sheep and goats. Caseous lymphadenitis is a widely spread chronic infectious disease, transmitted mainly through the skin. In the present experiment, aspects of the antigenic recognition by humoral response of goats bred in extensive condition, naturally infected or immunized with a live attenuated vaccine (cepa 1002, Empresa Baiana de Desenvolvimento Agrícola), have been studied. Samples of sera from immunized and control animals were collected monthly for a twelve month period and analyzed by ELISA and Western blotting. The analysis of the Western blotting results showed that the antigenic pattern recognized by sera antibodies of immunized animals is similar in crossbred or pure race animals and in naturally infected ones as well. Protein bands with molecular weights between 20 and 94 kDa have been detected. By analysing those samples, it was possible to observe that different proteins are recognized with elapsing time after immunization.Corynebacterium pseudotuberculosis é um cocobacilo gram-positivo, patógeno intracelular facultativo de macrófagos, filogeneticamente relacionado com o Mycobacterium tuberculosis. É amplamente distribuído em algumas espécies de animais, causando a linfadenite caseosa em ovinos e caprinos. A linfadenite caseosa, de ocorrência mundial, é uma doença infecciosa crônica cuja transmissão se dá principalmente através da pele. No presente experimento, foram estudados aspectos do reconhecimento antigênico, pela resposta humoral, em caprinos criados em regime extensivo, naturalmente infectados ou imunizados com uma vacina viva (cepa 1002), atenuada, desenvolvida pela Empresa Baiana de Desenvolvimento Agrícola (EBDA). As amostras de soros dos animais imunizados e de controle, coletadas mensalmente por um período de doze meses, foram analisadas pelo ensaio imunoenzimático ELISA e pelo Western blotting, utilizando-se como antígenos o extrato bacteriano contendo exotoxina e sonicado bacteriano de uma cepa selvagem e da cepa 1002. A análise através do Western blotting revelou que o padrão de antígenos reconhecidos pelos anticorpos séricos de animais imunizados, sem raça definida (srd) ou de duas raças puras, bem como animais srd naturalmente infectados, é semelhante, verificando-se bandas protéicas com pesos moleculares entre 20 e 94 kDa. Esta análise possibilitou observar-se que diferentes proteínas são reconhecidas ao longo da imunização

An empirical analysis of conviction patterns, change over the life-course and external influences in relation to sexual offending behaviour

This PhD uses statistical analysis and qualitative interviews to analyse behaviour patterns in the context of causal theories of sexual offending and desistance from it, with a particular emphasis on socio-cultural reasons why people offend, stop offending, or offend at different points in life. This research makes an original contribute to the literature in a number of ways. There are six main findings from this research that contribute to the literature in this area. One of the key findings is that there is substantial heterogeneity of offending behaviour amongst sexual offenders, suggesting that there is no one-size-fits-all approach for prevention, intervention or management. There was support in the research for a link between sexual offending and prolific non-sexual offending, but this only appeared to be one of several different sexual offending pathways. Other groups of offenders displayed considerable specialism in their offending (in terms of type of sexual offence and the fact that they had often only been convicted of sexual offences). This was magnified by the finding that offending rates were generally lower for sexual convictions than for other convictions: in fact, the vast majority of people in the dataset only had convictions for one sexual offence. There was evidence from the qualitative interviews that adverse life events were a contributory factor to sexual offending, and the thesis has found that there is support for both psychological and socio-cultural causes (including gender-based elements), as well as an interaction between the two. It also suggested that there is evidence that sexual offending is not stable over the life-course, and that situational factors appear to be important in terms of determining behavioural change. Implications for prevention, intervention and management of sexual offenders are discussed