1,266 research outputs found

    Elevation modelling and palaeo-environmental interpretation in the Siwa area (Egypt): Application of SAR interferometry and radargrammetry to COSMO-SkyMed imagery

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    PublishedJournal Article© 2015 Elsevier B.V. Digital elevation models produced from COSMO-SkyMed imagery were used to delineate palaeo-drainage in a wide area surrounding the Siwa and Al-Jaghbub oases of the western Sahara Desert (Egypt and Libya).This new generation of synthetic aperture radar imagery is suitable for this purpose because of its high spatial resolution and capacity to penetrate dry surface sediments. Different techniques such as radar interferometry and radargrammetry were used to produce digital elevation models. These were assessed for accuracy and then combined to produce a single elevation model of the area. The resulting elevation model was used to support the geological study and palaeo-environmental interpretation of the area. It revealed buried features of the landscape, including inactive palaeo-drainage systems. Drainage features were extracted from the elevation model using geographical information systems; results were combined and assessed with respect to geological field data, as well as data from the literature. Previous studies in the area suggest that a wide river, probably the old Nile River, flowed into the Libyan palaeo-Sirte before the Late Messinian drawdown of the Mediterranean Sea. During the Late Messinian lowering of the sea the fluvial system changed shape and carved deep canyons throughout north-eastern Africa. The reported findings on the key Siwa area were used to precisely delineate the physiography of the modern drainage network and to confirm findings from our previous geological research in the area.We gratefully acknowledge Ruggero Matteucci and Johannes Pignatti (La Sapienza, University of Rome), Francesco Checchi (ENI S.p.A., IOEC), Filippo Bonciani and Debora Graziosi (University of Siena) for their collaboration. Research was supported by the ASI (Id 2262) in the framework of the COSMO-SkyMed Announcement of Opportunity project “Application of COSMO-SkyMed data for geological researches in Egypt and Libya”

    Apparent stress-strain relationships in experimental equipment where magnetorheological fluids operate under compression mode

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    Abstract: This paper presents an experimental investigation of two different magnetorheological ( MR) fluids, namely, water-based and hydrocarbon-based MR fluids in compression mode under various applied currents. Finite element method magnetics was used to predict the magnetic field distribution inside the MR fluids generated by a coil. A test rig was constructed where the MR fluid was sandwiched between two flat surfaces. During the compression, the upper surface was moved towards the lower surface in a vertical direction. Stress-strain relationships were obtained for arrangements of equipment where each type of fluid was involved, using compression test equipment. The apparent compressive stress was found to be increased with the increase in magnetic field strength. In addition, the apparent compressive stress of the water-based MR fluid showed a response to the compressive strain of greater magnitude. However, during the compression process, the hydrocarbon-based MR fluid appeared to show a unique behaviour where an abrupt pressure drop was discovered in a region where the apparent compressive stress would be expected to increase steadily. The conclusion is drawn that the apparent compressive stress of MR fluids is influenced strongly by the nature of the carrier fluid and by the magnitude of the applied current

    Comparison between Two Different Two-Stage Transperineal Approaches to Treat Urethral Strictures or Bladder Neck Contracture Associated with Severe Urinary Incontinence that Occurred after Pelvic Surgery: Report of Our Experience

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    Introduction. The recurrence of urethral/bladder neck stricture after multiple endoscopic procedures is a rare complication that can follow prostatic surgery and its treatment is still controversial. Material and Methods. We retrospectively analyzed our data on 17 patients, operated between September 2001 and January 2010, who presented severe urinary incontinence and urethral/bladder neck stricture after prostatic surgery and failure of at least four conservative endoscopic treatments. Six patients underwent a transperineal urethrovesical anastomosis and 11 patients a combined transperineal suprapubical (endoscopic) urethrovesical anastomosis. After six months the patients that presented complete incontinence and no urethral stricture underwent the implantation of an artificial urethral sphincter (AUS). Results. After six months 16 patients were completely incontinent and presented a patent, stable lumen, so that they underwent an AUS implantation. With a mean followup of 50.5 months, 14 patients are perfectly continent with no postvoid residual urine. Conclusions. Two-stage procedures are safe techniques to treat these challenging cases. In our opinion, these cases could be managed with a transperineal approach in patients who present a perfect operative field; on the contrary, in more difficult cases, it would be preferable to use the other technique, with a combined transperineal suprapubical access, to perform a pull-through procedure

    Novel Double Triple Bend Achromat (DTBA) lattice design for a next generation 3 GeV Synchrotron Light Source

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    The Double Triple Bend Achromat (DTBA) lattice~\cite{DTBAipac16} is a novel lattice design for a next generation 3 GeV Synchrotron Light Source. Starting from a modification of the Hybrid Multi Bend Achromat (HMBA) lattice~\cite{ESRF} developed at ESRF and inspired by the Double-Double Bend Achromat (DDBA) lattice~\cite{Diamond1, Diamond2} developed at Diamond, DTBA combines the advantages of both cells. The typical MBA lattice cells have one straight section dedicated to an insertion device, whereas this new cell layout has two such drifts, thus increasing the fraction of available space for the installation of insertion devices. The DTBA lattice achieves an emittance of 132 pm\sim\mathrm{132~pm}, a dynamic aperture of ±10±1 mm\mathrm{\sim\pm10\pm1~mm} (calculated at the injection point), an injection efficiency of 88±5%\mathrm{\sim\mathrm88\pm5\%} and a lifetime of 1.4±0.2 h\mathrm{1.4\pm0.2~h} with errors. The characteristics of DTBA, the methodology and results of the linear and non-linear optics optimisations, with and without the presence of errors, are presented in detail

    Levels of autotrophy and heterotrophy in mesophotic corals near the end photic zone

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    Mesophotic corals live at ~30-150 m depth and can sustain metabolic processes under light-limited conditions by enhancing autotrophy through specialized photoadaptations or increasing heterotrophic nutrient acquisition. These acclimatory processes are often species-specific, however mesophotic ecosystems are largely unexplored and acclimation limits for most species are unknown. This study examined mesophotic coral ecosystems using a remotely operated vehicle (Ashmore Reef, Western Australia at 40 – 75m depth) to investigate the trophic ecology of five species of scleractinian coral (from genera Leptoseris, Pachyseris, and Craterastrea) using stable isotope analyses (δ13C and δ15N) of host and symbiont tissues and protein concentration. Trophic strategies were analyzed between species and between overall corals sampled above and below the end-photic point, where light is only 1% of surface irradiance. Results showed species-specific differences in resource use. Leptoseris hawaiiensis, L. scabra, and P. speciosa had similar Δ13C values (δ13C host - δ13C symbiont) approaching zero ( \u3c 0.5 ‰) which indicated greater dependence on symbiont autotrophy. In contrast, Leptoseris glabra and Craterastrea levis had higher Δ13C values (1.4 to 3.5 ‰) which indicated a greater reliance on external carbon sources. The latter two species also demonstrated tight nitrogen recycling within the holobiont, exhibiting low Δ15N values (host δ15N - symbiont δ15N = \u3c 0.5 ‰), compared to more autotrophic species (Δ15N = \u3e 1.2 ‰). Some species demonstrated the ability to maintain metabolic processes despite substantially reduced light availability (0.5 – 2% of surface irradiance). This research challenges our knowledge of acclimation limits for many scleractinian corals and contributes novel information for Ashmore Reef, the Western Australia region and mesophotic ecosystems in general, and critically examines common methods used to interpretate trophic ecology with bulk stable isotopes δ13C and δ15N

    Mobile Daily Centre (Mdc) for Elder People with Cognitive Impairment: a Retrospective Observational Study

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    Introduction Trieste is a city characterized by a high mean age of the resident population, with 6,000 people with a cognitive impairment. Evidences show that is necessary to have a multidisciplinary approach, making alliances with the social network and families, while dealing with people with cognitive impairment. Because of this, the 3rd catchment district has developed a Mobile Daily Centre that aims to promote health, abilities and socialization giving the possibilities for these people to stay in a social context. Objectives Evaluating the impact of the Mobile Daily Centre on QoL of people with Cognitive Impairment. Aims Considering the rate of hospitalization and access to the first aid unit at the general hospital. Methods Retrospective Observational Study for the period between 01.01.2012 and 30.04.2014 on people in charge to the MDC. We have considered socio-demographic variables such as age, gender, care-givers; clinical variables such as psychopharmacotherapy and acetylcolinesterase-inhibitors drugs; rates of hospitalization, number of accesses to the first aid unit and of interventions of the MDC. Results in the period of the study 20 patients have been followed by the MDC; half of them had a psycho-pharmacological prescription. Very low rates of institutionalization have been detected. Conclusions MDC, in these small numbers, has shown to reduce the number of improper institutionalizations while guaranteeing to the elder people to maintain their abilities and socialization and to their care-givers periods of relief. Moreover, it promotes social inclusion and destigmatization. These results suggest that more territorial work and further studies should be done

    NEUROBEHAVIORAL FUNCTIONS, SERUM PROLACTIN AND PLASMA RENIN ACTIVITY OF MANGANESE-EXPOSED WORKERS

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    Objective of this study was to assess effects of manganese (Mn) exposure on 56 workers employed in a Mn welding workshop of a machine building factory in Taiyuan (Shanxi Province, P.R. China) for a mean period of 16.1 years. The mean air Mn level in the workshop was 138.4 μg/m3. Neurobehavioral Core Test Battery (NCTB), including the Profile of Mood States (POMS), was performed. Blood pressure (BP) increase following immediate stand-up (BP-IS), serum prolactin (PRL) and plasma renin activity (PRA) in supine position were also determined. Most of the NCTB scores of the Mn-exposed workers were lower than those of the controls, while the POMS scores were higher, indicating a Mn-induced impairment of neurophysiological functions and a deflection of mood towards negative emotion states. PRL values of the Mn-exposed workers were higher than those of the controls. BP-IS of Mn-exposed workers was significantly lower than that of the controls. PRA of the same workers was augmented more than 200 %. In the Mn-exposed workers, the higher PRL values are possibly due to a reduced inhibitory effect on pituitary lactotrope cells by the tubero-infundibular dopamine system; the decreased BP-IS was referred to imbalance between the sympathetic and parasympathetic activities, whereas the higher basal PRA was thought to depend on neuroendocrine changes (including increased central sympathetic tone) and/or on a direct effect of Mn on renal juxta-glomerular cells. On the whole, this study demonstrates that occupational Mn exposure is responsible for neurobehavioral changes coexisting with alterations of neuroendocrine and humoral systems

    Does Exist a Differential Impact of Degarelix Versus LHRH Agonists on Cardiovascular Safety? Evidences From Randomized and Real-World Studies

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    The main systemic therapy for the management of hormone-sensitive prostate cancer (PC) is androgen deprivation therapy (ADT), with the use of long-acting luteinizing hormone releasing-hormone (LHRH) agonists considered the main form of ADT used in clinical practice to obtain castration in PC. The concomitant administration of antiandrogens for the first weeks could reduce the incidence of clinical effects related to the testosterone flare-up in the first injection of LHRH. On the contrary, Gonadotropin Rh (GnRH) antagonists produce a rapid decrease of testosterone levels without the initial flare-up, with degarelix commonly used in clinical practice to induce castration in PC patients. Even if no long-term data are reported in terms of survival to define a superiority of GnRH or LHRH, for oncological efficacy and PC control, data from randomized clinical trials and from real-life experiences, suggest a difference in cardiovascular risk of patients starting ADT. The age-related decline in testosterone levels may represent a factor connected to the increase of cardiovascular disease risk, however, the role of ADT in increasing CV events remains controversial. For these reasons, the aim of the paper is to synthesize the difference in cardiovascular risk between LHRH and degarelix in patients undergoing ADT. A difference in cardiovascular risk could be indeed an important parameter in the evaluation of these two forms of castration therapy. The Randomized trials analyzed in this paper sustain a possible protective role for degarelix versus LHRH agonists in reducing the rate of new CV events and interventions in the short-term period. On the contrary, real-word data are contradictory in different national experiences and are strongly conditioned by huge differences between the LHRH agonists group and the degarelix group
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