Una actividad física eficiente ante el reto de una sociedad de jóvenes influenciada por el modernismo y la tecnología

Actualmente los jóvenes se encuentran influenciados por un estilo de vida dominado por la modernidad y los avances tecnológicos, lo que deriva en una vida sedentaria que produce efectos nocivos en todos los sentidos y todos los ámbitos. Esto, aunado a los programas de un sistema institucional educativo y deportivo con innumerables carencias, nos lleva a una situación más complicada, en la que se añaden factores perjudiciales que abarcan la ignorancia, la incapacidad y los intereses personales, que no nos ayudan a edificar alternativas que comiencen a funcionar. Es primordial el establecimiento de una solución pronta y efectiva, encaminada a sistematizar una actividad física adecuada, basada en argumentos científicos y métodos acordes, que nos provean los diversos beneficios que su práctica otorga y nos ayuden a detener el proceso de deterioro físico, al cual el ritmo de vida actual no arroja

In vivo Neutralization of Pro-inflammatory Cytokines During Secondary Streptococcus pneumoniae Infection Post Influenza A Virus Infection

An overt pro-inflammatory immune response is a key factor contributing to lethal pneumococcal infection in an influenza pre-infected host and represents a potential target for therapeutic intervention. However, there is a paucity of knowledge about the level of contribution of individual cytokines. Based on the predictions of our previous mathematical modeling approach, the potential benefit of IFN-γ- and/or IL-6-specific antibody-mediated cytokine neutralization was explored in C57BL/6 mice infected with the influenza A/PR/8/34 strain, which were subsequently infected with the Streptococcus pneumoniae strain TIGR4 on day 7 post influenza. While single IL-6 neutralization had no effect on respiratory bacterial clearance, single IFN-γ neutralization enhanced local bacterial clearance in the lungs. Concomitant neutralization of IFN-γ and IL-6 significantly reduced the degree of pneumonia as well as bacteremia compared to the control group, indicating a positive effect for the host during secondary bacterial infection. The results of our model-driven experimental study reveal that the predicted therapeutic value of IFN-γ and IL-6 neutralization in secondary pneumococcal infection following influenza infection is tightly dependent on the experimental protocol while at the same time paving the way toward the development of effective immune therapies

Particle Swarm Optimization Algorithm with a Bio-Inspired Aging Model

A Particle Swarm Optimization with a Bio-inspired Aging Model (BAM-PSO) algorithm is proposed to alleviate the premature convergence problem of other PSO algorithms. Each particle within the swarm is subjected to aging based on the age-related changes observed in immune system cells. The proposed algorithm is tested with several popular and well-established benchmark functions and its performance is compared to other evolutionary algorithms in both low and high dimensional scenarios. Simulation results reveal that at the cost of computational time, the proposed algorithm has the potential to solve the premature convergence problem that affects PSO-based algorithms; showing good results for both low and high dimensional problems. This work suggests that aging mechanisms do have further implications in computational intelligence

Ānāpāna: Neuro-engineering of Mindfulness

Meditation benefits have been widely supported by many research works. It is considered a natural way of reducing stress, depression, and other anxiety disorders. However, meditation process is a breathe pursuing task that requires long time training to avoid the so-called mind wandering. In this work, we propose a neural-feedback system that detects when mind wanders and generates an audible signal, this way patient’s attention is recovered back again. Finally, we support our approach by testing the system on novice and advanced meditators

Calculo del nivel de conciencia utilizando computación paralela

En patologías neurológicas existe un estado conocido como sindorme de “Locked-in” en el cual el paciente tiene conciencia pero es incapaz de comunicarse con el mundo exterior. Este trabajo en progreso, muestra una aplicación innovadora de computación paralela, para optimizar de la implementación del algoritmo de cálculo de conciencia propuesto por Tononi [2]. Describe el algoritmo del cálculo y propone una metodología innovadora para involucrar computación paralela en su implementación.

Calculo del nivel de conciencia utilizando computación paralela

En patologías neurológicas existe un estado conocido como sindorme de “Locked-in” en el cual el paciente tiene conciencia pero es incapaz de comunicarse con el mundo exterior. Este trabajo en progreso, muestra una aplicación innovadora de computación paralela, para optimizar de la implementación del algoritmo de cálculo de conciencia propuesto por Tononi [2]. Describe el algoritmo del cálculo y propone una metodología innovadora para involucrar computación paralela en su implementación.

Ānāpāna: Neuro-engineering of Mindfulness

Meditation benefits have been widely supported by many research works. It is considered a natural way of reducing stress, depression, and other anxiety disorders. However, meditation process is a breathe pursuing task that requires long time training to avoid the so-called mind wandering. In this work, we propose a neural-feedback system that detects when mind wanders and generates an audible signal, this way patient’s attention is recovered back again. Finally, we support our approach by testing the system on novice and advanced meditators