BSA-PEG Hydrogel: A Novel Protein-Ligand Binding 3D Matrix

Hydrogel materials have good biomimetic properties and high potential for biomedical and bioanalytical applications. In this work, a hydrogel of serum albumin crosslinked with poly-(ethylene glycol) was prepared and characterized for its water content, protein structure and stability. The ability of the hydrogel to bind small molecule ligands with different hydrophobicity was evaluated using a homologous series of amphiphiles (NBD-Cn, n = 4, 6 and 8) and the calculated binding affinities were similar to that of free protein in solution. Overall, the results indicate this type of hydrogel system as a convenient tool for studying the binding of xenobiotics to tissue proteins.info:eu-repo/semantics/publishedVersio

Litoestratigrafía del “Dominio Esquisto-Grauváquico” en Portugal: una reevaluación

A synthesis of the knowledge of the Schist-Greywacke Domain (SGD) in Portugal is here presented. Until recently, this sequence assumed the designation of Dúrico-Beirão Supergroup composed by the Douro Group (DG) and the Beiras Group (BG). The DG is considered of Neoproterozoic – Cambrian age and the BG is of Neoproterozoic age. The identification and mapping in the BG of an unconformity as the Cadomian unconformity identified in Spain, which splits the Neoproterozoic in “lower Alcudian” and “upper Alcudian”, is a turning point for the understanding and establishment of consistent stratigraphic sequences that now compose the Fróia and the Lousã groups assembled in the Beiras Supergroup. These new groups are correlated with the Neoproterozoic sequences currently recognized in Spain: the Lousã group is equivalent to the Ibor Group (upper Alcudian) and the Fróia Group is equivalent pro parte, to the Domo Extremeño Supergroup.  En este trabajo se presenta una síntesis del conocimiento actual del Dominio del Complejo Esquisto-Grauváquico en Portugal. Hasta al presente esta secuencia ha sido designada como Supergrupo Dúrico-Beirão, compuesto por el Grupo Douro (GD) y por el Grupo Beiras (GB). El GD se consideraba de edad Ediacárico superior – Cámbrico inferior y el GB era atribuido al Neoproterozoico. La identificación y cartografía en el GB de una discordancia correlacionable con la del Cadomiense identificada en España, que divide el Neoproterozoico en "Alcudiense inferior" y "Alcudiense superior", es un punto de inflexión para la comprensión y el establecimiento de secuencias estratigráficas consistentes, que ahora componen los grupos Fróia y Lousã reunidos en el Supergrupo Beiras. Estos nuevos grupos se correlacionan con las secuencias neoproterozoicas actualmente reconocidas en España: el Grupo Lousã es equivalente al Grupo Ibor (Alcudiense Superior) y el Grupo Fróia es equivalente, pro parte, al Supergrupo Domo Extremeño

Litoestratigrafía del “Dominio Esquisto-Grauváquico” en Portugal: una reevaluación

[Abstract] A synthesis of the knowledge of the Schist-Greywacke Domain (SGD) in Portugal is here presented. Until recently, this sequence assumed the designation of Dúrico-Beirão Supergroup composed by the Douro Group (DG) and the Beiras Group (BG). The DG is considered of Neoproterozoic – Cambrian age and the BG is of Neoproterozoic age. The identification and mapping in the BG of an unconformity as the Cadomian unconformity identified in Spain, which splits the Neoproterozoic in “lower Alcudian” and “upper Alcudian”, is a turning point for the understanding and establishment of consistent stratigraphic sequences that now compose the Fróia and the Lousã groups assembled in the Beiras Supergroup. These new groups are correlated with the Neoproterozoic sequences currently recognized in Spain: the Lousã group is equivalent to the Ibor Group (upper Alcudian) and the Fróia Group is equivalent pro parte, to the Domo Extremeño Supergroup.[Resumen] En este trabajo se presenta una síntesis del conocimiento actual del Dominio del Complejo Esquisto-Grauváquico en Portugal. Hasta al presente esta secuencia ha sido designada como Supergrupo Dúrico-Beirão, compuesto por el Grupo Douro (GD) y por el Grupo Beiras (GB). El GD se consideraba de edad Ediacárico superior – Cámbrico inferior y el GB era atribuido al Neoproterozoico. La identificación y cartografía en el GB de una discordancia correlacionable con la del Cadomiense identificada en España, que divide el Neoproterozoico en "Alcudiense inferior" y "Alcudiense superior", es un punto de inflexión para la comprensión y el establecimiento de secuencias estratigráficas consistentes, que ahora componen los grupos Fróia y Lousã reunidos en el Supergrupo Beiras. Estos nuevos grupos se correlacionan con las secuencias neoproterozoicas actualmente reconocidas en España: el Grupo Lousã es equivalente al Grupo Ibor (Alcudiense Superior) y el Grupo Fróia es equivalente, pro parte, al Supergrupo Domo Extremeño

The effect of magnetic anisotropy on the spin configurations of patterned La0.7Sr0.3MnO3 elements

International audienceWe study the effect of magnetocrystalline anisotropy on the magnetic configurations of La0:7Sr0:3MnO3 bar and triangle elements using photoemission electron microscopy imaging. The dominant remanent state is a low energy flux-closure state for both thin (15 nm) and thick (50 nm) elements. The magnetocrystalline anisotropy, which competes with the dipolar energy, causes a strong modification of the spin configuration in the thin elements, depending on the shape, size and orientation of the structures. We investigate the magnetic switching processes and observe in triangular shaped elements a displacement of the vortex core along the easy axis for an external magnetic field applied close to the hard axis, which is well reproduced by micromagnetic simulations