O Sole Mio (Just Like the Sunrise)

[Verse 1]Fond recollections, they are mem’ry’s trea-suresWithin my treasure chest apart from all the rest,One recollection brings a thousand pleasures,The mem-’ry of the day when I first met you. [Verse 2]Be-cause I love you, I shall always cherishThe golden past I knew so sweet because of you,Each memory of you can not fade or perish;In-to a life of dark-ness you brought sunshine [Verse 1]Che bella cosa ‘na iurnata’e soleN’aria serena doppo ‘na tempesta!Pe’llaria fresca pare già ‘nà festaChe bella cosa ‘na iurnata’e sole. Luceno e llastre d’a fenesta toia‘na la vannara canta’e se ne vanta,E petramente torce, spanne e canta,Luceno e llastre d’a fenesta toa. [Chorus]Just like the sunrise you came to me,Just like the sun - rise from out the sea,Because my road was dreary You came one day to light my way.Just like the way. Ma n’atu sole cchiù bello, ohi-ne,‘O sole mio sta nfronte a te.‘O sole, o sole mio sta nffronte a te, sta nfronteaMa n’atu te

Use of biodegradable mulching in vegetable production

Trials were carried out in Liguria during three years (2004-2006) to evaluate the use of innovative starch based bioplastics for soil mulching. All trials carried out in open field as well as in greenhouse on different vegetable crops demonstrated the effectiveness of biodegradable films in controlling weeds and in increasing yield. The use of biodegradable mulching films found application in integrated production regulations set up by the regional authority and it is potentially adoptable in an organic farming context

Clinical Consequences and Functional Impact of the Rare S737F CFTR Variant and Its Responsiveness to CFTR Modulators

S737F is a Cystic Fibrosis (CF) transmembrane conductance regulator (CFTR) missense variant. The aim of our study was to describe the clinical features of a cohort of individuals carrying this variant. In parallel, by exploiting ex vivo functional and molecular analyses on nasal epithelia derived from a subset of S737F carriers, we evaluated its functional impact on CFTR protein as well as its responsiveness to CFTR modulators. We retrospectively collected clinical data of all individuals bearing at least one S737F CFTR variant and followed at the CF Centre of Tuscany region (Italy). Nasal brushing was performed in cooperating individuals. At study end clinical data were available for 10 subjects (mean age: 14 years; range 1–44 years; 3 adult individuals). Five asymptomatic subjects had CF, 2 were CRMS/CFSPID and 3 had an inconclusive diagnosis. Ex vivo analysis on nasal epithelia demonstrated different levels of CF activity. In particular, epithelia derived from asymptomatic CF subjects and from one of the subjects with inconclusive diagnosis showed reduced CFTR activity that could be rescued by treatment with CFTR modulators. On the contrary, in the epithelia derived from the other two individuals with an inconclusive diagnosis, the CFTR-mediated current was similar to that observed in epithelia derived from healthy donors. In vitro functional and biochemical analysis on S737F-CFTR expressed in immortalized bronchial cells highlighted a modest impairment of the channel activity, that was improved by treatment with ivacaftor alone or in combination with tezacaftor/elexacaftor. Our study provide evidence towards the evaluation of CFTR function on ex vivo nasal epithelial cell models as a new assay to help clinicians to classify individuals, in presence of discordance between clinical picture, sweat test and genetic profile

Pages in the Wind : A Reader

" This is a bedside book, composed by artists participating in the international exhibition of the 52nd International Art Exhibition La Biennale di Venezia. The writtings that appear in these pages, whether entire or in excerpted form, have been chosen by them from their reading and are being passed along in the expectation that tgey will be of more than casual interest to others. " -- Page 5 of book

FESTIVAL DE LA CHANSON POPULAIRE ITALIENNE / Luciano VIRGILI et l'orchestre de Dino OLIVIERI

Titre uniforme : [Non ti scordar di me]Titre uniforme : [Non ti scordar di me]Comprend : Addio, Signora - Piccola santa - Cara piccina - Amor di pastorello - Non ti scordardi me - Vivere - Ladra - Portami tante rose - Chiove - Primo Amore - Balochei e profumiBnF-Partenariats, Collection sonore - BelieveContient une table des matière