Proton induced Dark Count Rate degradation in 150-nm CMOS Single-Photon Avalanche Diodes

Proton irradiation effects on a Single-Photon Avalanche Diodes (SPADs) device manufactured using a 150-nm CMOS process are presented. An irradiation campaign has been carried out with protons of 20 MeV and 24 MeV on several samples of a test chip containing SPADs arrays with two different junction layouts. The dark count rate distributions have been analyzed as a function of the displacement damage dose. Annealing and cooling have been investigated as possible damage mitigation approaches. We also discuss, through a space radiation simulation, the suitability of such devices on several space mission case-studies.Comment: This is an author-created, un-copyedited version of an article accepted for publication/published in Nuclear Instruments and Methods in Physics Research Section A. The Version of Record is available online at https://doi.org/10.1016/j.nima.2019.16272

First results from an aging test of a prototype RPC for the LHCb Muon System

Recent results of an aging test performed at the CERN Gamma Irradiation Facility on a single--gap RPC prototype developed for the LHCb Muon System are presented. The results are based on an accumulated charge of about 0.45 C/cm$^2$, corresponding to about 4 years of LHCb running at the highest background rate. The performance of the chamber has been studied under several photon flux values exploiting a muon beam. A degradation of the rate capability above 1 kHz/cm$^2$ is observed, which can be correlated to a sizeable increase of resistivity of the chamber plates. An increase of the chamber dark current is also observed. The chamber performance is found to fulfill the LHCb operation requirements.Comment: 6 pages, 9 figures, presented at the International Workshop on Aging Phenomena in Gaseous Detectors'', DESY-Hamburg (Germany), October 200

Preliminary results of an aging test of RPC chambers for the LHCb Muon System

The preliminary results of an aging test performed at the CERN Gamma Irradiation Facility on a single--gap RPC prototype developed for the LHCb Muon System are presented. The results are based on an accumulated charge density of 0.42 C/cm^2, corresponding to about 4 years of LHCb running at the highest background rate. We observe a rise in the dark current and noise measured with source off. The current drawn with source on steadily decreased, possibly indicating an increase of resistivity of the chamber plates. The performance of the chamber, studied with a muon beam under several photon flux values, is found to still fulfill the LHCb operation requirements.Comment: 4 pages, 6 figures, presented at RPC2001, VIth Workshop on Resistive Plate Chambers and Related Detectors, November 26-27 2001, Coimbra, Portuga

New results from an extensive aging test on bakelite Resistive Plate Chambers

We present recent results of an extensive aging test, performed at the CERN Gamma Irradiation Facility on two single--gap RPC prototypes, developed for the LHCb Muon System. With a method based on a model describing the behaviour of an RPC under high particle flux conditions, we have periodically measured the electrode resistance R of the two RPC prototypes over three years: we observe a large spontaneous increase of R with time, from the initial value of about 2 MOhm to more than 250 MOhm. A corresponding degradation of the RPC rate capabilities, from more than 3 kHz/cm2 to less than 0.15 kHz/cm2 is also found.Comment: 6 pages, 7 figures, presented at Siena 2002, 8th Topical Seminar on Innovative Particle and Radiation Detectors 21-24 October 2002, Siena, Ital

Simultaneous High-Purity Enantiomeric Resolution of Conglomerates Using Magnetic Substrates

Applying magnetic substrates, magnetized perpendicular to the surface, we were able to crystallize from racemic solution pure conglomerates of several molecules. The resolution is based on the spin-dependent charge reorganization (SDCR) effect. By having two surfaces with opposite magnetization, it was possible to simultaneously crystallize on each surface a different enantiomer. The method does not require any seeding or chemical modification and is generally employable to any conglomerate. A system is presented for performing the separation, while the racemic mixture flows between the two magnetic surfaces

Seismological and geotechnical aspects of the Mw=6.3 l’Aquila earthquake in central Italy on 6 April 2009

The L’Aquila earthquake occurred on April 6 2009 at 03:32:39 local time. The earthquake (Mw=6.3) was located in the central Italy region of Abruzzo. Much of the damage occurred in the capital city of L’Aquila, a city of approximate population 73000, although many small villages in the surrounding region of the middle Aterno river valley were also significantly damaged. In the weeks following the earthquake, the Geo-Engineering Extreme Events Reconnaissance (GEER) international team, comprised of members from different European countries and the U.S., was assembled to provide post-earthquake field reconnaissance. The GEER team focused on the geological, seismological, and geotechnical engineering aspects of the event. We describe the principal seismological findings related to this earthquake including moment tensors of the main shock and two triggered events, the aftershock pattern and its variation with time, tectonic deformations associated with the main shock, surface fault rupture, and the inferred fault rupture plane. We describe damage patterns on a village-to-village scale and on a more local scale within the city of L’Aquila. In many cases the damage patterns imply site effects, as neighbouring villages on rock and soil had significantly different damage intensities (damage more pronounced on softer sediments). The April 6 mainshock was the best-recorded event to date in Italy. We present metadata related to the recording sites and then present preliminary comparisons of the data to GMPEs. Those comparisons support the notion of faster distance attenuation in Italy relative to the average for active regions as reflected in NGA GMPEs. Several incidents of ground failure are then discussed, including a number of rockfalls and minor landslides. Perhaps the most significant incidents of ground failure occurred at Lake Sinizzo, for which we describe a number of slumps and spreads around the lake perimeter. This is documented using field observations as well as LIDAR and bathymetric data

Effect of magnetic impurities on the vortex lattice properties in NbSe2 single crystals

We report a pronounced peak effect in the magnetization of CoxNbSe2 single crystals with critical temperatures T-c ranging between 7.1 and 5.0 K, and MnxNbSe2 single crystals with critical temperatures down to 3.4 K. We correlate the peak effect in magnetization with the structure of the vortex lattice across the peak-effect region using scanning-tunneling microscopy. Magnetization measurements show that the amplitude of the peak effect in the case of CoxNbSe2 exhibits a nonmonotonic behavior as a function of the Co content, reaching a maximum for concentration of Co of about 0.4 at. % (corresponding to a T-c of 5.7 K) and after that gradually decreasing in amplitude with the increase in the Co content. The normalized value of the peak position H-p/H-c2 has weak dependence on Co concentration. In the case of MnxNbSe2 the features of the peak effect as a function of the Mn content are different and they can be understood in terms of strong pinning

STM studies of CoxNbSe2 and MnxNbSe2

Cobalt and Manganese intercalated NbSe(2) single crystals have been synthesized and characterized by DC magnetization and scanning tunnelling microscopy (STM) at low temperatures. We observed a pronounced peak effect in magnetization for both Co and Mn intercalated samples that we further investigated by low temperature STM. A structural phase transition of the vortex lattice (VL) has been observed for applied magnetic fields corresponding to the peak in magnetization

Symmetry breaking at the (111) interfaces of SrTiO3{_3} hosting a 2D-electron system

We used x-ray absorption spectroscopy to study the orbital symmetry and the energy band splitting of (111) LaAlO${_3}$/SrTiO${_3}$ and LaAlO${_3}$/EuTiO${_3}$/SrTiO${_3}$ heterostructures, hosting a quasi two-dimensional electron system (q2DES), and of a Ti-terminated (111) SrTiO${_3}$ single crystal, also known to form a q2DES at its surface. We demonstrate that the bulk tetragonal Ti-3d D${_4}$${_h}$ crystal field is turned into trigonal D${_3}$${_d}$ crystal field in all cases. The symmetry adapted a${_1}$${_g}$ and e${^\pi_g}$ orbitals are non-degenerate in energy and their splitting, \Delta, is positive at the bare STO surface but negative in the heterostructures, where the a${_1}$${_g}$ orbital is lowest in energy. These results demonstrate that the interfacial symmetry breaking induced by epitaxial engineering of oxide interfaces has a dramatic effect on their electronic properties, and it can be used to manipulate the ground state of the q2DES.Comment: 6 pages article, plus 5 pages supplementary informatio

Development of broad-spectrum human monoclonal antibodies for rabies post-exposure prophylaxis

Currently available rabies post-exposure prophylaxis (PEP) for use in humans includes equine or human rabies immunoglobulins (RIG). The replacement of RIG with an equally or more potent and safer product is strongly encouraged due to the high costs and limited availability of existing RIG. In this study, we identified two broadly neutralizing human monoclonal antibodies that represent a valid and affordable alternative to RIG in rabies PEP. Memory B cells from four selected vaccinated donors were immortalized and monoclonal antibodies were tested for neutralizing activity and epitope specificity. Two antibodies, identified as RVC20 and RVC58 (binding to antigenic site I and III, respectively), were selected for their potency and broad-spectrum reactivity. In vitro, RVC20 and RVC58 were able to neutralize all 35 rabies virus (RABV) and 25 non-RABV lyssaviruses. They showed higher potency and breath compared to antibodies under clinical development (namely CR57, CR4098, and RAB1) and commercially available human RIG. In vivo, the RVC20-RVC58 cocktail protected Syrian hamsters from a lethal RABV challenge and did not affect the endogenous hamster post-vaccination antibody response