Realising the technological promise of smartphones in addiction research and treatment: An ethical review

Background Smartphone technologies and mHealth applications (or apps) promise unprecedented scope for data collection, treatment intervention, and relapse prevention when used in the field of substance abuse and addiction. This potential also raises new ethical challenges that researchers, clinicians, and software developers must address. Aims This paper aims to identify ethical issues in the current uses of smartphones in addiction research and treatment. Methods A search of three databases (PubMed, Web of Science and PsycInfo) identified 33 studies involving smartphones or mHealth applications for use in the research and treatment of substance abuse and addiction. A content analysis was conducted to identify how smartphones are being used in these fields and to highlight the ethical issues raised by these studies. Results Smartphones are being used to collect large amounts of sensitive information, including personal information, geo-location, physiological activity, self-reports of mood and cravings, and the consumption of illicit drugs, alcohol and nicotine. Given that detailed information is being collected about potentially illegal behaviour, we identified the following ethical considerations: protecting user privacy, maximising equity in access, ensuring informed consent, providing participants with adequate clinical resources, communicating clinically relevant results to individuals, and the urgent need to demonstrate evidence of safety and efficacy of the technologies. Conclusions mHealth technology offers the possibility to collect large amounts of valuable personal information that may enhance research and treatment of substance abuse and addiction. To realise this potential researchers, clinicians and app-developers must address these ethical concerns to maximise the benefits and minimise risks of harm to users

Argument schemes for two-phase democratic deliberation

A formal two-phase model of democratic policy deliberation is presented, in which in the first phase sufficient and necessary criteria for proposals to be accepted are determined (the ‘acceptable’ criteria) and in the second phase proposals are made and evaluated in light of the acceptable criteria resulting from the first phase. Such a separation gives the discussion a clear structure and prevents time and resources from being wasted on evaluating arguments for proposals based on unacceptable criteria. Argument schemes for both phases are defined and formalised in a logical framework for structured argumentation. The process of deliberation is abstracted from and it is assumed that both deliberation phases result in a set of arguments and attack and defeat relations between them. The acceptability status of criteria and proposals within the resulting argumentation framework is then evaluated using preferred semantics. For cases where preferences are required to choose between proposals, inference rules for deriving preferences between sets from an ordering of their elements are given.MediamaticsElectrical Engineering, Mathematics and Computer Scienc

The Complexity of Repairing, Adjusting, and Aggregating of Extensions in Abstract Argumentation

We study the computational complexity of problems that arise in abstract argumentation in the context of dynamic argumentation, minimal change, and aggregation. In particular, we consider the following problems where always an argumentation framework F and a small positive integer k are given. - The Repair problem asks whether a given set of arguments can be modified into an extension by at most k elementary changes (i.e., the extension is of distance k from the given set). - The Adjust problem asks whether a given extension can be modified by at most k elementary changes into an extension that contains a specified argument. - The Center problem asks whether, given two extensions of distance k, whether there is a "center" extension that is a distance at most (k-1) from both given extensions. We study these problems in the framework of parameterized complexity, and take the distance k as the parameter. Our results covers several different semantics, including admissible, complete, preferred, semi-stable and stable semantics

Learning processes and their mediating role between teaching quality and student achievement: a systematic review

This systematic literature review was conducted in order to further the understanding of how learning processes act as mediators between teaching quality and student achievement. Eighteen quantitative studies were included for analysis. In 24 of 53 mediation paths (45%) learning processes were identified and confirmed as mediators and in 29 mediation paths (55%) non-significant mediating effects were found. The complexity of the included studies’ context, methodology, conceptualization, and operationalization posed challenges for a quantitative synthesis. The findings provide some initial ideas for how to better design future research into indirect effects of teaching quality

Gravitational wave astronomy

The first decade of the new millenium should see the first direct detections of gravitational waves. This will be a milestone for fundamental physics and it will open the new observational science of gravitational wave astronomy. But gravitational waves already play an important role in the modeling of astrophysical systems. I review here the present state of gravitational radiation theory in relativity and astrophysics, and I then look at the development of detector sensitivity over the next decade, both on the ground (such as LIGO) and in space (LISA). I review the sources of gravitational waves that are likely to play an important role in observations by first- and second-generation interferometers, including the astrophysical information that will come from these observations. The review covers some 10 decades of gravitational wave frequency, from the high-frequency normal modes of neutron stars down to the lowest frequencies observable from space. The discussion of sources includes recent developments regarding binary black holes, spinning neutron stars, and the stochastic background.Comment: 29 pages, 2 figures, as submitted for special millenium issue of Classical and Quantum Gravit

Improving the health and welfare of people who live in slums

Summary In the first paper in this Series we assessed theoretical and empirical evidence and concluded that the health of people living in slums is a function not only of poverty but of intimately shared physical and social environments. In this paper we extend the theory of so-called neighbourhood effects. Slums offer high returns on investment because beneficial effects are shared across many people in densely populated neighbourhoods. Neighbourhood effects also help explain how and why the benefits of interventions vary between slum and non-slum spaces and between slums. We build on this spatial concept of slums to argue that, in all low-income and-middle-income countries, census tracts should henceforth be designated slum or non-slum both to inform local policy and as the basis for research surveys that build on censuses. We argue that slum health should be promoted as a topic of enquiry alongside poverty and health

Minimum Sensitivity Based Robust Beamforming with Eigenspace Decomposition

An enhanced eigenspace-based beamformer (ESB) derived using the minimum sensitivity criterion is proposed with significantly improved robustness against steering vector errors. The sensitivity function is defined as the squared norm of the appropriately scaled weight vector and since the sensitivity function of an array to perturbations becomes very large in the presence of steering vector errors, it can be used to find the best projection for the ESB, irrespective of the distribution of additive noises. As demonstrated by simulation results, the proposed method has a better performance than the classic ESBs and the previously proposed uncertainty set based approach

Processing and Transmission of Information

Contains reports on seven research projects

A Comparative Study of Defeasible Argumentation and Non-monotonic Fuzzy Reasoning for Elderly Survival Prediction Using Biomarkers

Computational argumentation has been gaining momentum as a solid theoretical research discipline for inference under uncertainty with incomplete and contradicting knowledge. However, its practical counterpart is underdeveloped, with a lack of studies focused on the investigation of its impact in real-world settings and with real knowledge. In this study, computational argumentation is compared against non-monotonic fuzzy reasoning and evaluated in the domain of biological markers for the prediction of mortality in an elderly population. Different non-monotonic argument-based models and fuzzy reasoning models have been designed using an extensive knowledge base gathered from an expert in the field. An analysis of the true positive and false positive rate of the inferences of such models has been performed. Findings indicate a superior inferential capacity of the designed argument-based models

Study of the a_0(980) meson via the radiative decay phi->eta pi^0 gamma with the KLOE detector

We have studied the phi->a_0(980) gamma process with the KLOE detector at the Frascati phi-factory DAPhNE by detecting the phi->eta pi^0 gamma decays in the final states with eta->gamma gamma and eta->pi^+ pi^- pi^0. We have measured the branching ratios for both final states: Br(phi->eta pi^0 gamma)=(7.01 +/- 0.10 +/- 0.20)x10^-5 and (7.12 +/- 0.13 +/- 0.22)x10^-5 respectively. We have also extracted the a_0(980) mass and its couplings to eta pi^0, K^+ K^-, and to the phi meson from the fit of the eta pi^0 invariant mass distributions using different phenomenological models.Comment: 17 pages, 6 figures, submitted to Physics Letters B. Corrected typos in eq.