ALMA Observation of NGC5135: The Circumnuclear CO(6-5) and Dust Continuum Emission at 45 Parsec Resolution[⋆\star]

We present high-resolution (0.17\arcsec $\times$ 0.14\arcsec) Atacama Large Millimeter/submillimeter Array (ALMA) observations of the CO\,(6-5) line, and 435\um\ dust continuum emission within a $\sim$9\arcsec $\times$ 9\arcsec\ area centered on the nucleus of the galaxy NGC\,5135. NGC\,5135 is a well-studied luminous infrared galaxy that also harbors a Compton-thick active galactic nucleus (AGN). At the achieved resolution of 48 $\times$ 40\,pc, the CO\,(6-5) and dust emissions are resolved into gas "clumps" along the symmetrical dust lanes associated with the inner stellar bar. The clumps have radii between $\sim$45-180\,pc and CO\,(6-5) line widths of $\sim$60-88\,\kms. The CO\,(6-5) to dust continuum flux ratios vary among the clumps and show an increasing trend with the \FeII/Br-$\gamma$ ratios, which we interpret as evidence for supernova-driven shocked gas providing a significant contribution to the \co65\ emission. The central AGN is undetected in continuum, nor in CO\,(6-5) if its line velocity width is no less than $\sim$\,40\,\kms. We estimate that the AGN contributes at most 1\% of the integrated CO\,(6-5) flux of 512 $\pm$ 24$\,$Jy\kms\ within the ALMA field of view, which in turn accounts for $\sim$32\% of the CO\,(6-5) flux of the whole galaxy.Comment: 21 pages, 12 figures, Accepted for publication in Ap

An Hα\alpha Imaging Survey of the Low-surface-brightness Galaxies Selected from the Fall Sky Region of the 40%\% ALFALFA \ion{H}{1} Survey

We present the observed H$\alpha$ flux and derived star formation rates (SFRs) for a fall sample of low$-$surface$-$brightness galaxies (LSBGs). The sample is selected from the fall sky region of the 40$\%$ ALFALFA {\ion{H}{1}} survey $-$ SDSS DR7 photometric data, and all the $H\alpha$ images were obtained using the 2.16 m telescope, operated by the National Astronomy Observatories, Chinese Academy of Sciences. A total of 111 LSBGs were observed and $H\alpha$ flux was measured in 92 of them. Though almost all the LSBGs in our sample are {\ion{H}{1}}$-$rich, their SFRs derived from the extinction and filter$-$transmission$-$corrected $H\alpha$ flux, are less than 1M_{\sun}$yr^{-1}$. LSBGs and star forming galaxies have similar {\ion{H}{1}} surface densities, but LSBGs have much lower SFRs and SFR surface densities than star$-$forming galaxies. Our results show that LSBGs deviate from the Kennicutt-Schmidt law significantly, which indicate that they have low star formation efficiency. The SFRs of LSBGs are close to average SFRs in Hubble time and support the previous arguments that most of the LSBGs are stable systems and they tend to seldom contain strong interactions or major mergers during their star formation histories

An Hα\alpha Imaging Survey of the Low-surface-brightness Galaxies Selected from the Fall Sky Region of the 40%\% ALFALFA \ion{H}{1} Survey

We present the observed H$\alpha$ flux and derived star formation rates (SFRs) for a fall sample of low$-$surface$-$brightness galaxies (LSBGs). The sample is selected from the fall sky region of the 40$\%$ ALFALFA {\ion{H}{1}} survey $-$ SDSS DR7 photometric data, and all the $H\alpha$ images were obtained using the 2.16 m telescope, operated by the National Astronomy Observatories, Chinese Academy of Sciences. A total of 111 LSBGs were observed and $H\alpha$ flux was measured in 92 of them. Though almost all the LSBGs in our sample are {\ion{H}{1}}$-$rich, their SFRs derived from the extinction and filter$-$transmission$-$corrected $H\alpha$ flux, are less than 1M_{\sun}$yr^{-1}$. LSBGs and star forming galaxies have similar {\ion{H}{1}} surface densities, but LSBGs have much lower SFRs and SFR surface densities than star$-$forming galaxies. Our results show that LSBGs deviate from the Kennicutt-Schmidt law significantly, which indicate that they have low star formation efficiency. The SFRs of LSBGs are close to average SFRs in Hubble time and support the previous arguments that most of the LSBGs are stable systems and they tend to seldom contain strong interactions or major mergers during their star formation histories

S100 Calcium Binding Protein A10, A Novel Oncogene, Promotes the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma

Hepatocarcinogenesis is a highly complicated process that is promoted by a series of oncogenes. Our study aims to identify novel oncogenes promoting hepatocellular carcinoma (HCC) by bioinformatic analysis and experimental validation. Here, we reported that S100 calcium binding protein A10 (S100A10) was screened out as a potential novel oncogene in HCC by integrated analysis of OEP000321 dataset and the Cancer Genome Atlas (TCGA)-Liver-Cancer data. Furthermore, S100A10 was highly expressed in HCC samples and observably associated with patients’ overall survival (OS). Overexpression of S100A10 in Hep3B and Huh-7 increased the cell proliferation, whereas downregulation of S100A10 in SK-Hep-1 and HepG2 cells reduced the cell viability to almost stop growing. In vivo tumor growth assays showed that S100A10-overexpressing Hep3B cells had a larger tumor size than control. Moreover, S100A10 overexpression promoted Hep3B cells migration and invasion, and S100A10 knockdown inhibited SK-Hep-1 cells migration and invasion, in vitro. In conclusion, it is demonstrated that S100A10 is a novel oncogene in HCC, indicating a possible novel therapeutic strategy of HCC

ALMA [N \i\i ] 205 \mu m Imaging Spectroscopy of the Lensed Submillimeter galaxy ID 141 at redshift 4.24

We present the Atacama Large Millimeter/submillimeter Array (ALMA) observation of the Sub-millimeter galaxy (SMG) ID 141 at z=4.24 in the [N II] 205 $\mu$m line (hereafter [N II]) and the underlying continuum at (rest-frame) 197.6 $\mu$m. Benefiting from lensing magnification by a galaxy pair at z=0.595, ID 141 is one of the brightest z$>4$ SMGs. At the angular resolutions of $\sim1.2''$ to $1.5''$ ($1'' \sim6.9$ kpc), our observation clearly separates, and moderately resolves the two lensed images in both continuum and line emission at $\rm S/N>5$ . Our continuum-based lensing model implies an averaged amplification factor of $\sim5.8$ and reveals that the de-lensed continuum image has the S\'ersic index $\simeq 0.95$ and the S\'ersic radius of $\sim0.18'' (\sim 1.24$ kpc). Furthermore, the reconstructed [N II] velocity field in the source plane is dominated by a rotation component with a maximum velocity of $\sim 300$ km/s at large radii, indicating a dark matter halo mass of $\sim 10^{12}M_{\odot}$. This, together with the reconstructed velocity dispersion field being smooth and modest in value ($<100$ km/s) over much of the outer parts of the galaxy, favours the interpretation of ID 141 being a disk galaxy dynamically supported by rotation. The observed [N II]/CO (7-6) and [N II]/[C II] 158 $\mu$m line luminosity ratios, which are consistent with the corresponding line ratio vs. far-infrared color correlation from local luminous infrared galaxies, imply a de-lensed star formation rate of ($1.8\pm 0.6)\times10^3M_\odot$/yr and provide an independent estimate on the size of the star-forming region $0.7^{+0.3}_{-0.3}$ kpc in radius.Comment: 13 pages, 6 figures, 2 tables, accepted by ApJ, lensing model code can be found here https://gitlab.com/cxylzlx/tiny_len

Intrinsic Morphology of Ultra-diffuse Galaxies

With the published data of apparent axis ratios for 1109 ultra-diffuse galaxies (UDGs) located in 17 low-redshift (z~ 0.020 - 0.063) galaxy clusters and 84 UDGs in 2 intermediate-redshift (z~ 0.308 - 0.348) clusters, we take advantage of a Markov Chain Monte Carlo approach and assume a ubiquitous triaxial model to investigate the intrinsic morphologies of UDGs. In contrast to the conclusion of Burkert (2017), i.e., the underlying shapes of UDGs are purely prolate ($C=B<A$), we find that the data favor the oblate-triaxial models ($C<B\lesssim A$) over the nearly prolate ones. We also find that the intrinsic morphologies of UDGs are relevant to their stellar masses/luminosities, environments, and redshifts. First, for the low-redshift UDGs in the same environment, the more-luminous ones are always thicker than the less-luminous counterparts, possibly due to the more voilent internal supernovae feedback or external tidal interactions for the progenitors of the more-luminous UDGs. The UDG thickness dependence on luminosity is distinct from that of the typical quiescent dwarf ellipticals (dEs) and dwarf spheroidals (dSphs) in the local clusters and groups, but resembles that of massive galaxies; in this sense, UDGs may not be simply treated as an extension of the dE/dSph class with similar evolutionary histories. Second, for the low-redshift UDGs within the same luminosity range, the ones with smaller cluster-centric distances are more puffed-up, probably attributed to tidal interactions. Finally, the intermediate-redshift cluster UDGs are more flattened, which plausibly suggests a `disky' origin for high-redshift, initial UDGs.Comment: Accepted for publication in ApJ; new versio

The atomic gas of star-forming galaxies at z∼\sim0.05 as revealed by the Five-hundred-meter Aperture Spherical Radio Telescope

We report new HI observations of four z$\sim$0.05 star-forming galaxies undertaken during the commissioning phase of the Five-hundred-meter Aperture Spherical Radio Telescope (FAST). FAST is the largest single-dish telescope with a 500 meter aperture and a 19-Beam receiver. Exploiting the unprecedented sensitivity provided by FAST, we aim to study the atomic gas, via the HI 21cm emission line, in low-$z$ star-forming galaxies taken from the Valpara\'iso ALMA/APEX Line Emission Survey (VALES) project. Together with previous ALMA CO($J=1-0$) observations, the HI data provides crucial information to measure the gas mass and dynamics. As a pilot HI survey, we targeted four local star-forming galaxies at $z\sim0.05$. In particular, one of them has already been detected in HI by the Arecibo Legacy Fast ALFA survey (ALFALFA), allowing a careful comparison. We use an ON-OFF observing approach that allowed us to reach an rms of 0.7mJy/beam at a 1.7km/s velocity resolution within only 20 minutes ON-target integration time. We demonstrate the great capabilities of the FAST 19-beam receiver for pushing the detectability of the HI emission line of extra-galactic sources. The HI emission line detected by FAST shows good consistency with the previous ALFALFA results. Our observations are put in context with previous multi-wavelength data to reveal the physical properties of these low-$z$ galaxies. We find that the CO($J=1-0$) and HI emission line profiles are similar. The dynamical mass estimated from the HI data is an order of magnitude higher than the baryon mass and the dynamical mass derived from the CO observations, implying that the mass probed by dynamics of HI is dominated by the dark matter halo. In one case, a target shows an excess of CO($J=1-0$) in the line centre, which can be explained by an enhanced CO($J=1-0$) emission induced by a nuclear starburst showing high velocity dispersion.Comment: 5 pages, 3 figures, 2 appendix, A&A Letter accepte