The effect of preoperative stoma site marking on quality of life in patients undergoing ostomy surgery

The purpose of this study was to determine if preoperative stoma site marking by a Wound, Ostomy, Continence (WOC) nurse affects patient quality of life. This study used a descriptive design with a convenience sample of 25 ostomy patients. Sixty-three surveys were mailed to study participants and the response rate was 40%. Ten subjects (40%) had their stoma site marked by a WOC nurse preoperatively and fifteen subjects did not. Eleven participants reported that their ostomy was permanent (44%), while fourteen of the participants (56%) state they had a temporary stoma. Thirteen of the subjects had elective ostomy surgery (52%) and twelve (48%) had an ostomy created under emergent conditions. Overall quality of life scores did not differ between the marked and unmarked subjects. However, subjects who did not have their stoma site marked preoperatively had greater problems with pouch leakage (p=.0055) than those who were marked preoperatively

Donnez au suivant ou le transfert d'expertise en soutien à l'insertion professionnelle

Comprend des références bibliographiques.La directrice du regroupement PERFORMA et l’une des répondantes locales de ce dernier au Cégep de Saint-Jérôme nous présentent le Microprogramme de 2e cycle en insertion professionnelle en enseignement au collégial (MIPEC), une formation qui permet le développement des compétences essentielles à l’enseignement collégial. Structuré comme un programme d’études, le MIPEC est un exemple de communautés d’apprentissage génératrices de communautés de pratique, en ce sens que les professeurs débutants sont formés et encadrés par des tuteurs qui sont généralement eux-mêmes des professeurs d’expérience, voire à l’aube d’une retraite, profitant du programme pour transmettre la richesse de leur savoir-faire et de leur expertise, favorisant ainsi l’insertion professionnelle au sein des collèges

Decoupling Simulated Annealing From Massive Multiplayer Online Role-Playing Games in RAID

End-users agree that compact technology are an interesting new topic in the field of electri- cal engineering, and physicists concur. In fact, few futurists would disagree with the deploy- ment of Byzantine fault tolerance, demonstrates the structured importance of cryptography. We construct a novel algorithm for the simulation of write-ahead logging (JDL), validating that Byzantine fault tolerance can be made peer-to- peer, classical, and stable. It is often an important mission but is supported by previous work in the field

Genetic heterogeneity of HER2 amplification and telomere shortening in papillary thyroid carcinoma

Extensive research is dedicated to understanding if sporadic and familial papillary thyroid carcinoma are distinct biological entities. We have previously demonstrated that familial papillary thyroid cancer (fPTC) cells exhibit short relative telomere length (RTL) in both blood and tissues and that these features may be associated with chromosome instability. Here, we investigated the frequency of HER2 (Human Epidermal Growth Factor Receptor 2) amplification, and other recently reported genetic alterations in sporadic PTC (sPTC) and fPTC, and assessed correlations with RTL and BRAF mutational status. We analyzed HER2 gene amplification and the integrity of ALK, ETV6, RET, and BRAF genes by fluorescence in situ hybridization in isolated nuclei and paraffin-embedded formalin-fixed sections of 13 fPTC and 18 sPTC patients. We analyzed BRAFV600E mutation and RTL by qRT-PCR. Significant HER2 amplification (p = 0.0076), which was restricted to scattered groups of cells, was found in fPTC samples. HER2 amplification in fPTCs was invariably associated with BRAFV600E mutation. RTL was shorter in fPTCs than sPTCs (p < 0.001). No rearrangements of other tested genes were observed. These findings suggest that the association of HER2 amplification with BRAFV600E mutation and telomere shortening may represent a marker of tumor aggressiveness, and, in refractory thyroid cancer, may warrant exploration as a site for targeted therapy

Analysis of programmed cell death in Tobacco Bright Yellow-2 cells.

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ST. MARY OF EGYPT IN BL MS COTTON OTHO B. X: NEW TEXTUAL EVIDENCE FOR AN OLD ENGLISH SAINT\u27S LIFE

Scholarship of the anonymous Old English prose Life of St. Mary of Egypt ranges from source studies and linguistic analyses to explorations of Anglo-Saxon female sexuality and comparisons to saints\u27 lives translated by the monk Ælfric, but all of these studies have been based on either the text extant in BL MS Cotton Julius E. vii or on W. W. Skeat\u27s edition of the Julius manuscript, Ælfric\u27s Lives of Saints (1881-1900). There is, however, an as yet unedited fragmentary copy of the Old English Mary of Egypt in BL MS Cotton Otho B. x, a manuscript severely damaged by fire in 1731. Digital imaging of damaged manuscripts in concert with ultraviolet fluorescence and other special lighting techniques has been shown to be effective for restoring the legibility of previously inaccessible texts. By means of such digital facsimiles I have transcribed the text of Mary of Egypt in Otho B. x, have collated this text with Skeat\u27s edition, and have discovered that Otho B. x contains textual evidence not found in Julius E. vii. In this thesis, I present my findings and discuss the significance of this new textual evidence for the Old English Life of St. Mary of Egypt

Tribute to David Gregory, Esq.

The Board and Staff of the Maine Law Review dedicate this issue to the memory of Professor David Doliver Gregory, who passed away on December 9, 2000. The Maine legal community and the University of Maine School of Law mourn the loss of our beloved teacher, advocate, and friend. In the collective memory of his students, Professor Gregory will always be remembered for the Socratic genius that he employed so effectively in class; his keen wit, often accompanied by a knowing smile and a twinkle in his eyes; his passion for ferreting out seemingly elusive legal principles; and his compassion and warmth for those he instructed. Perhaps above all, Professor Gregory will be recalled as the archetypal Law Professor that he was. He was the rarest of educators, someone who taught us how to challenge ourselves intellectually, and who demonstrated both in his life and in his teaching that the law not only reaches all facets of society but also touches upon the most fundamental and important aspects of human existence itself. On January 17, 2001 hundreds of his colleagues and students gathered at the First Parish Church in Portland, Maine to celebrate Professor Gregory\u27s life. What follows are the remembrances delivered at the memorial service and two tributes from professional colleagues that give a picture of his life in the courtroom and the classroom

Antisense Oligonucleotides (ASOs) in Motor Neuron Diseases: A Road to Cure in Light and Shade

Antisense oligonucleotides (ASOs) are short oligodeoxynucleotides designed to bind to specific regions of target mRNA. ASOs can modulate pre-mRNA splicing, increase levels of functional proteins, and decrease levels of toxic proteins. ASOs are being developed for the treatment of motor neuron diseases (MNDs), including spinal muscular atrophy (SMA), amyotrophic lateral sclerosis (ALS) and spinal and bulbar muscular atrophy (SBMA). The biggest success has been the ASO known as nusinersen, the first effective therapy for SMA, able to improve symptoms and slow disease progression. Another success is tofersen, an ASO designed to treat ALS patients with SOD1 gene mutations. Both ASOs have been approved by the FDA and EMA. On the other hand, ASO treatment in ALS patients with the C9orf72 gene mutation did not show any improvement in disease progression. The aim of this review is to provide an up-to-date overview of ASO research in MNDs, from preclinical studies to clinical trials and, where available, regulatory approval. We highlight the successes and failures, underline the strengths and limitations of the current ASO research, and suggest possible approaches that could lead to more effective treatments