1,351 research outputs found
The hidden burden of adult allergic rhinitis : UK healthcare resource utilisation survey
Funding Funding for this survey was provided by Meda Pharma.Peer reviewedPublisher PD
Effects of allergen immunotherapy in the MASK-air study: a proof-of-concept analysis
info:eu-repo/semantics/publishedVersio
Barriers to Asthma Treatment in the United States: Results From the Global Asthma Physician and Patient Survey
BACKGROUND: The Global Asthma Physician and Patient (GAPP) survey evaluated the perceptions of both physicians and patients on the management of asthma. Here we present the results from the United States (US) subpopulation of the GAPP survey. METHODS: The GAPP Survey was a large, global study (physicians, n = 1733; patients, n = 1726; interviews, n = 3459). In the US, 208 adults (aged ≥ 18 years) with asthma and 224 physicians were recruited. Respondents were questioned using self-administered online interviews with close-ended questionnaires. RESULTS: Physician and patient responses were found to differ in regard to perception of time spent on asthma education, awareness of disease symptoms and their severity, asthma medication side effects, and adherence to treatment and the consequence of nonadherence. Comparison of the US findings with the global GAPP survey results suggest the US physician-patient partnership compared reasonably well with the other countries in the survey. Both patients and physicians cited a need for new asthma medication. CONCLUSIONS: Similar to the global GAPP survey, the US-specific findings indicate that in general there is a lack of asthma control, poor adherence to therapy, and room for improvement in patient-physician communication and partnership in treating asthma
A detector module with highly efficient surface-alpha event rejection operated in CRESST-II Phase 2
The cryogenic dark matter experiment CRESST-II aims at the direct detection
of WIMPs via elastic scattering off nuclei in scintillating CaWO crystals.
We present a new, highly improved, detector design installed in the current run
of CRESST-II Phase 2 with an efficient active rejection of surface-alpha
backgrounds. Using CaWO sticks instead of metal clamps to hold the target
crystal, a detector housing with fully-scintillating inner surface could be
realized. The presented detector (TUM40) provides an excellent threshold of
keV and a resolution of keV (at
2.60keV). With significantly reduced background levels, TUM40 sets
stringent limits on the spin-independent WIMP-nucleon scattering cross section
and probes a new region of parameter space for WIMP masses below
3GeV/c. In this paper, we discuss the novel detector design and the
surface-alpha event rejection in detail.Comment: 9 pages, 6 figure
Exploring CEvNS with NUCLEUS at the Chooz Nuclear Power Plant
Coherent elastic neutrino-nucleus scattering (CENS) offers a unique way
to study neutrino properties and to search for new physics beyond the Standard
Model. Nuclear reactors are promising sources to explore this process at low
energies since they deliver large fluxes of (anti-)neutrinos with typical
energies of a few MeV. In this paper, a new-generation experiment to study
CENS is described. The NUCLEUS experiment will use cryogenic detectors
which feature an unprecedentedly low energy threshold and a time response fast
enough to be operated in above-ground conditions. Both sensitivity to
low-energy nuclear recoils and a high event rate tolerance are stringent
requirements to measure CENS of reactor antineutrinos. A new experimental
site, denoted the Very-Near-Site (VNS) at the Chooz nuclear power plant in
France is described. The VNS is located between the two 4.25 GW
reactor cores and matches the requirements of NUCLEUS. First results of on-site
measurements of neutron and muon backgrounds, the expected dominant background
contributions, are given. In this paper a preliminary experimental setup with
dedicated active and passive background reduction techniques is presented.
Furthermore, the feasibility to operate the NUCLEUS detectors in coincidence
with an active muon-veto at shallow overburden is studied. The paper concludes
with a sensitivity study pointing out the promising physics potential of
NUCLEUS at the Chooz nuclear power plant
Results on MeV-scale dark matter from a gram-scale cryogenic calorimeter operated above ground
Models for light dark matter particles with masses below 1 GeV/c are a
natural and well-motivated alternative to so-far unobserved weakly interacting
massive particles. Gram-scale cryogenic calorimeters provide the required
detector performance to detect these particles and extend the direct dark
matter search program of CRESST. A prototype 0.5 g sapphire detector developed
for the -cleus experiment has achieved an energy threshold of
eV, which is one order of magnitude lower than previous
results and independent of the type of particle interaction. The result
presented here is obtained in a setup above ground without significant
shielding against ambient and cosmogenic radiation. Although operated in a
high-background environment, the detector probes a new range of light-mass dark
matter particles previously not accessible by direct searches. We report the
first limit on the spin-independent dark matter particle-nucleon cross section
for masses between 140 MeV/c and 500 MeV/c.Comment: 6 pages, 6 figures, v3: ancillary files added, v4: high energy
spectrum (0.6-12keV) added to ancillary file
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