16 research outputs found

    A Mobitz type II atrioventricular block in multicentric ischemic stroke

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    Cardiac and cerebrovascular illnesses are major causes of mortality and morbidity. Thromboembolisms, which are the result of cardiac arrhythmia, are important causes of ischemic stroke. In this study, we present a rare case of multicentric ischemic stroke induced by Mobitz type II atrioventricular block.The Pan African Medical Journal 2016;2

    The relation between preset distinguishing sequences and synchronizing sequences

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    We study the relation between synchronizing sequences and preset distinguishing sequences which are some special sequences used in finite state machine based testing. We show that the problems related to preset distinguishing sequences can be converted into related problems of synchronizing sequences. Using the results existing in the literature for synchronizing sequences, we offer several reflections of these results for preset distinguishing sequences. Although computing a preset distinguishing sequence is PSPACE-hard , we do identify a class of machines for which computing a preset distinguishing sequence can be performed in polynomial time and argue that this class is practically relevant. We also present an experimental study to compare the performance of exponential brute-force and polynomial heuristic algorithms to compute a preset distinguishing sequence

    Possible Associations of APE1 Polymorphism with Susceptibility and HOGG1 Polymorphism with Prognosis in Gastric Cancer

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    Background: Multiple genetic and epigenetic alterations in several genes are implicated in the multistep process of human gastric carcinogenesis. In this study, we examined the polymorphisms of six DNA repair genes: APE1, HOGG1, XRCC1, XRCC3, XPD, and XPG in patients with gastric cancer (GC). Patients and Methods: Forty patients with GC and 247 controls were included in this study. DNA polymorphisms were determined by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) method. Results: The frequency of the Asp/Glu genotype and Glu allele of APE1 in patients with GC was significantly higher than in the control group (p=0.05). We also observed a higher frequency of the Ser/Ser genotype of HOGG1 in grade III tumors, and in tumors with metastasis to adjacent tissue and solid organs (p<0.05). Conclusion: Our results suggest that (i) APE1 gene polymorphism may be associated with GC risk and (ii) HOGG1 gene polymorphism may be informative in the prognosis of GC
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