308 research outputs found

    Mapping SMEs financial literacy research: bibliometric analysis and literature review

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    Financial literacy in SMEs constitutes an emerging research field, increasing its scientific production exponentially in recent years, and in a very heterogeneous way. The purpose of this paper its to review 88 contributions for the period 2005-2020 through bibliometric techniques. Specifically, we carry out a co-occurrence and co-citation analysis of the keywords and cited references to obtain two thematic clusters and four theoretical roots. Thus, through its combination in five thematic groups, we develop an integrative framework that allow us to identify the research paths addressed, and propose important lines of future research, providing a research guide for scholars.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Financial literacy in SMES: a bibliometric analysis of an emerging topic

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    The purpose of this study is to review the existing literature on financial literacy (FL) in SMEs in general, and particularly in family SMEs, and describe the current state of publications in this area through the use of bibliometric techniques. The review of 88 documents, in the period between 2005 and 2020, will identify the agents involved (countries, organizations, journals, authors, publications) that have the greatest influence on the development of this research topic. In turn, the content analysis through the co-occurrence of the author's keywords will detect the driving themes. In the first analysis carried out, it is evident the positive impact that FL has on the performance and access to financing of the SMEs. Other lines of growing interest and still little developed are the effect of FL on firm capital structure and innovation. The main contribution of this research is to provide coverage to the existing gap in FL in SMEs bibliometric analysis, helping scholars to locate the existing gaps in this research topic.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Se retiró la Agustina hecha un demonio. Artículo determinado + antropónimo en documentación judicial del siglo XVIII

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    En este artículo se estudia la estructura «artículo determinado + nombre propio de persona» (el Antonio) en un corpu s de documentos del Reino de Granada (Granada, Málaga, Almería) del siglo XVIII. El corpus está formado por veintiuna declaraciones de testigos pertenecientes a diez juicios distintos. En los estudios previos de carácter diacrónico, se afirma que esta estructura sobreespecificada se emplea para ofrecer valoración negativa sobre el referente humano. Queremos comprobar si los ejemplos de nuestro corpus sirven también para expresar conceptualizaciones negativas. Además de la pauta «artículo + nombre propio», analizamos otras estructuras con antropónimo, que se emplean para hacer referencia en la narración a los protagonistas: «el dicho + nom bre propio» (el dicho Juan Pérez, nombre propio escueto (Juan Pérez), aposición explicativa (Juan Pérez alcalde del lugar) y aposición idendficadva {el abogado Juan Pérez).Proyectos de referencia P09HUM 4466, (Junta de Andalucía / Fondos FEDER ) y FFI2010-18736 (MICINN / Fondos FEDER)

    Selection of Tumor-Specific Cytotoxic T Lymphocytes in Acute Myeloid Leukemia Patients Through the Identification of T-Cells Capable to Establish Stable Interactions With the Leukemic Cells: “Doublet Technology”

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    The relevance of the immune system in cancer has long been studied. Autologous adoptive T cell therapies, based on the use of tumor infiltrating lymphocytes (TILs), have made great progress in recent years for the treatment of solid tumors, especially melanoma. However, further work is needed to isolate tumor-reactive T cells among patients diagnosed with hematologic malignancies. The dynamics of the interaction between T cells and antigen presenting cells (APC) dictate the quality of the immune responses. While stable joints between target cells and T lymphocytes lead to the induction of T cell activation and immune response, brief contacts contribute to the induction of immune-tolerance. Taking advantage of the strong interaction between target cell and activated T-cells, we show the feasibility to identify and isolate tumor-specific cytotoxic T lymphocytes (CTLs) from acute myeloid leukemia (AML) patients by flow cytometry. Using this technology, CTLs bound through T cell receptor (TCR) to tumor cells can be identified in peripheral blood and bone marrow and subsequently selected and isolated by FACS-based cell sorting. These CTLs display higher percentage of effector cells and marked cytotoxic activity against AML blasts. In conclusion, we have developed a new procedure to identify and select specific cytotoxic T cells in patients diagnosed with acute myeloid leukemia.Instituto de Salud Carlos III PFIS-FI12/00189Instituto de Salud Carlos III ISCIII PI14/02074Instituto de Salud Carlos III PI11/02366Instituto de Salud Carlos III PI17/02177European Union (ERDF/ESF, Investing in your future)CIBER CB16/12/0048

    Analysis of pesticide residues in honeybee (Apis mellifera L.) and in corbicular pollen. Exposure in citrus orchard with an integrated pest management system

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    In the last years, the honeybee population is facing growing threats such as expansion of pathogens, incorrect use of phytosanitary products and environmental contaminants, loss or fragmentation of habitat, invasive species and climate change. The citrus cropping by Integrated Pest Management (IPM) in Spain combines strategies to reduce pest populations preventing environmental problems and reducing levels of damage by using chemicals only when it is strictly necessary. The goal of this study is to develop a simple analytical method to evaluate pesticide residue levels in honeybees and corbicular pollen when honeybees are exposed to plant protection products (PPPs) used in integrated pest management citrus orchards. The proposed method is based in an ultrasound assisted extraction procedure followed by a dispersive solid phase extraction (d-SPE) clean-up with alumina and LC-MS/MS pesticides determination. The method was validated in samples of honeybee and corbicular pollen for 10 pesticides commonly used in citrus orchards under IPM. This procedure was compared with QuEChERS methodologies for these matrices. The developed method was applied to determine pesticides in both matrices in a two -year study in citrus orchards.info:eu-repo/semantics/acceptedVersio

    Evaluation of residue levels of imidacloprid and thiamethoxam after foliar application to the citrus varieties Lane Late, Valencia Late, Rohde Summer, and Nules

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    Neonicotinoids are used to protect citrus trees against pests. Dissipation and persistence of neonicotinoids in pollen and nectar of citrus trees after foliar applications and their potential exposure to pollinators have not been well characterized. Field studies were conducted using three orange and one mandarin varieties to compare the imidacloprid and thiamethoxam residue levels and their decline in pollen and nectar after treatments in pre-bloom close to flowering period and their persistence 1 yr after treatment. The possible risk to honeybees was assessed. In nectar, thiamethoxam and imidacloprid residues were between 61 and 99% lower than in pollen, depending on the citrus variety or/and the days after treatment when applied close to blooming. At the end of the flowering period, imidacloprid in pollen and nectar was not detected in the mandarin variety after treatment in pre-bloom, whereas for thiamethoxam, no residues were detected in nectar but 10 ng/g was detected in pollen. There were no quantifiable levels of residues for either neonicotinoids in pollen or nectar during the flowering period of the following year. Neonicotinoid residue levels and their decline in nectar and pollen in citrus depended on the timing of applications relative to flowering and on the citrus variety. The absence of neonicotinoid residues 1 yr out after foliar applications in all varieties assayed demonstrated that none of the neonicotinoids tested were persistent. The results could be different in other citrus varieties, and therefore, also the exposure assessment for managed pollinators.info:eu-repo/semantics/acceptedVersio

    The Influence of Host Fruit and Temperature on the Body Size of Adult Ceratitis capitata (Diptera: Tephritidae) under Laboratory and Field conditions

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    The adult body size of the Mediterranean fruit ßy, Ceratitis capitata (Wiedemann) (Diptera: Tephritidae), varies in natural conditions. Body size is an important Þtness indicator in the Mediterranean fruit ßy;largerindividuals are more competitive at mating and have a greater dispersion capacity and fertility. Both temperature during larval development and host fruit quality have been cited as possible causes for this variation.We studied the inßuence of host fruit and temperature during larval development on adult body size (wing area) in the laboratory, and determined body size variation in Þeld populations of the Mediterannean fruit ßy in eastern Spain. Field ßies measured had two origins: 1) ßies periodically collected throughout the year in Þeld traps from 32 citrus groves, during the period 2003Ð2007; and 2) ßies evolved from different fruit species collected between June and December in 2003 and 2004. In the lab, wing area of male and female adults varied signiÞcantly with temperature during larval development, being larger at the lowest temperature. Adult size also was signiÞcantly different depending on the host fruit in which larvae developed. The size of the ßies captured at the Þeld, either from traps or from fruits, varied seasonally showing a gradual pattern of change along the year. The largest individuals were obtained during winter and early spring and the smallest during late summer. In Þeld conditions, the size of the adult Mediterannean fruit ßy seems apparently more related with air temperature than with host fruit. The implications of this adult size pattern on the biology ofC. capitata and on the application of the sterile insect technique are discussed.We thank Apostolos Pekas for his useful comments on previous versions of the manuscript. This work was supported by the project RTA03-103-C6-3 assigned to F. G. 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