22,193 research outputs found
Coherent Imaging Spectroscopy of a Quantum Many-Body Spin System
Quantum simulators, in which well controlled quantum systems are used to
reproduce the dynamics of less understood ones, have the potential to explore
physics that is inaccessible to modeling with classical computers. However,
checking the results of such simulations will also become classically
intractable as system sizes increase. In this work, we introduce and implement
a coherent imaging spectroscopic technique to validate a quantum simulation,
much as magnetic resonance imaging exposes structure in condensed matter. We
use this method to determine the energy levels and interaction strengths of a
fully-connected quantum many-body system. Additionally, we directly measure the
size of the critical energy gap near a quantum phase transition. We expect this
general technique to become an important verification tool for quantum
simulators once experiments advance beyond proof-of-principle demonstrations
and exceed the resources of conventional computers
D-Brane Recoil and Supersymmetry Breaking as a Relaxation Process
We propose a new mechanism for the formation of conical singularities on
D-branes by means of recoil resulting from scattering of closed string states
propagating in the (large) transverse dimensions. By viewing the (spatial part
of the) four-dimensional world as a 3-brane with large transverse dimensions
the above mechanism can lead to supersymmetry obstruction at the TeV scale. The
vacuum remains supersymmetric while the mass spectrum picks up a supersymmetry
obstructing mass splitting. The state with ``broken'' supersymmetry is not an
equilibrium ground state, but is rather an excited state of the D-brane which
relaxes to the supersymmetric ground state asymptotically in (cosmic) time.Comment: 9 pages revtex, uses axodraw style (Arguments clarified, citations
added; no change in conclusions.
Time-resolved fluorescence microscopy to study biologically related applications using sol-gel derived and cellular media
Application of density functional theory in the synthesis of electroactive polymers
A wide range of conjugated organic compounds undergo anodic electropolymerisation to produce polymers of high conductivity. However, electrooxidation does not always result in the formation of electroactive materials, since some reactions produce insulating films or soluble oligomers. Density functional theory (DFT) has been used to predict the outcome of electropolymerisation reactions by calculating the unpaired electron π-spin density distribution of monomeric radical cations, in order to determine coupling positions in the resultant polymers. π-Spin densities calculated for pyrrole, thiophene and (E)-stilbene are found to be in good agreement with experimental values. DFT has been used to investigate the low conductivity and redox inactivity of poly[(E)-3-styrylthiophenes] and poly[(E)-2-styrylheterocycles]. High positive spin densities at the alkene spacer linkage in the corresponding monomeric radical cations were found, suggesting crosslinking of the polymers via the double bond. In contrast, electroactive polymers of improved conductivity are formed from the electropolymerisation of some (Z)-2-α,β-diarylacrylonitriles. For these monomers, DFT calculations show the positions of highest spin density to be located at the α-positions of the heterocyclic rings, suggesting the presence of α,α′-linked monomeric couplings necessary for electroactivity
Sequential simulation model development
Sequential simulation (SqS) is a physical form of simulation that recreates care pathway trajectories rather than single episodes of care. Current physical simulation in health care focuses on specific tasks or particular teams and settings. However, the patient perspective is a journey through the care system and not an isolated component. To date, SqS has been used for a range of applications, including training multidisciplinary teams on end-of-life care, developing integrated care approaches, quality improvement projects, designing new models of care, evaluating new interventions, and improving care of the deteriorating patient in an acute setting, to name but a few. Many applications are possible, and therefore the design process can be lengthy and complex. This article outlines an approach the author took over a 3-year period to generate a usable SqS model through empirical and theoretical data. The model draws on process, observational, survey, and evaluative data to generate an understanding of the key components that constitute the design process of an SqS. This approach resulted in an empirically and theoretically driven model that can be used and refined by others in the field of health-care simulation
Contextual influences on social enterprise management in rural and urban communities
The idea that difference exists between rural and urban enterprise activity is not new, the obvious comparators are measures such as social architecture, resource availability and accessibility. However, when the concept and practice of management in social enterprise is compared in these two contexts then there is opportunity to further our understanding of the contextual challenges encountered by social enterprise. In this paper six cases studies are compared and analysed: three cases are urban social enterprises and three classified as remote rural social enterprises. The urban cases are social enterprises located around Glasgow in the west of Scotland and are compared with three remote rural location studies, one on the Scottish mainland peninsula, the other in northern Scotland and the final case on a Scottish western island. We conclude that the main differences between remote rural and urban management of social enterprise are heavily nuanced by in-migration levels in both rural and urban locations, leadership and community needs and therefore deserving of context relevant policy
Factors contributing to the time taken to consult with symptoms of lung cancer: a cross-sectional study
<b>Objectives</b>: To determine what factors are associated with the time people take to consult with symptoms of lung cancer, with a focus on those from rural and socially deprived areas.
<b>Methods</b>: A cross-sectional quantitative interview survey was performed of 360 patients with newly diagnosed primary lung cancer in three Scottish hospitals (two in Glasgow, one in NE Scotland). Supplementary data were obtained from medical case notes. The main outcome measures were the number of days from (1) the date participant defined first symptom until date of presentation to a medical practitioner; and (2) the date of earliest symptom from a symptom checklist (derived from clinical guidelines) until date of presentation to a medical practitioner.
<b>Results</b>: 179 participants (50%) had symptoms for more than 14 weeks before presenting to a medical practitioner (median 99 days; interquartile range 31–381). 270 participants (75%) had unrecognised symptoms of lung cancer. There were no significant differences in time taken to consult with symptoms of lung cancer between rural and/or deprived participants compared with urban and/or affluent participants. Factors independently associated with increased time before consulting about symptoms were living alone, a history of chronic obstructive pulmonary disease (COPD) and longer pack years of smoking. Haemoptysis, new onset of shortness of breath, cough and loss of appetite were significantly associated with earlier consulting, as were a history of chest infection and renal failure.
<b>Conclusion</b>: For many people with lung cancer, regardless of location and socioeconomic status, the time between symptom onset and consultation was long enough to plausibly affect prognosis. Long-term smokers, those with COPD and/or those living alone are at particular risk of taking longer to consult with symptoms of lung cancer and practitioners should be alert to this
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