Enrichment of innate lymphoid cell populations in gingival tissue

Innate lymphoid cells (ILCs) are a population of lymphocytes that act as the first line of immunologic defense at mucosal surfaces. The ILC family in the skin, lungs, and gastrointestinal tissues has been investigated, and there are reports of individual subsets of ILCs in the oral tissues. We sought to investigate the whole ILC population (group 1, 2, and 3 subsets) in the murine gingivae and the lymph nodes draining the oral cavity. We show that ILCs made up a greater proportion of the whole CD45+ lymphocyte population in the murine gingivae (0.356% ± 0.039%) as compared with the proportion of ILCs in the draining lymph nodes (0.158% ± 0.005%). Cytokine profiling of the ILC populations demonstrated different proportions of ILC subsets in the murine gingivae versus the regional lymph nodes. The majority of ILCs in the draining lymph nodes expressed IL-5, whereas there were equal proportions of IFN-γ- and IL-5 expressing ILCs in the oral mucosa. The percentage of IL-17+ ILCs was comparable between the murine gingivae and the oral draining lymph nodes. These data suggest an enrichment of ILCs in the murine gingivae, and these ILCs reflect a cytokine profile discrepant to that of the local draining lymph nodes. These studies indicate diversity and enrichment of ILCs at the oral mucosal surface. The function of ILCs in the oral cavity remains to be determined; here, we provide a premise of ILC populations that merits future consideration in investigations of mouse models and human tissues

Effects of the Ionic Liquid Structure on porosity of lignin-derived carbon materials

Converting lignin into advanced porous carbon materials, with desirable surface functionalities, can be challenging. While lignin-derived carbons produced by pyrolysis at >600 °C develop porosity, they also simultaneously lose nearly all their surface functional groups. By contrast, pyrolysis of lignin at lower temperatures (e.g., <400 °C) results in the formation of nonporous char that retains some surface functionalities. However, copyrolysis of lignin with some ionic liquids (ILs) at lower temperatures offers an opportunity to produce porous carbon materials with both large surface areas and an abundance of surface functional groups. This study investigates the effects of IL properties (solubility, thermal, and ionic size) on the specific surface areas of lignin-derived carbons produced by copyrolysis of lignin and ILs at 350–400 °C for 20 min. It was found that ILs that have bulky anions and small cation sizes can induce porosity in lignin-derived carbons with large surface areas. Among 16 ILs that were tested, [C2MIm][NTF2] demonstrated the best performance; the inclusion of it in the copyrolysis process resulted in lignin-derived carbons with ∼528 m2 g–1 and 0.48 cm3 g–1. Lignin-derived carbons produced using no IL, [C2MIm][NTF2], and [C4MIm][OTF] were further characterized for morphology, interfacial chemical, and elemental properties. The copyrolysis of lignin and [C2MIm][NTF2], and [C4MIm][OTF] resulted in doping of heteroatoms (N and S) on the porous carbon materials during pyrolysis reaction. The present findings contribute to a better understanding of the main property of ILs responsible for creating porosity in lignin carbon during pyrolysis

Upsilon production in pp and pA collisions: from RHIC to the LHC

I discuss Upsilon production in pp collisions at RHIC, Tevatron and LHC energies, in particular the behaviour of the differential cross section in rapidity and the impact of QCD corrections on the P_T differential cross section. I also emphasise the very good agreement between the parameter-free predictions of the Colour-Singlet Model (CSM) and the first LHC data, especially in the region of low transverse momenta, which is the most relevant one for heavy-ion studies. I also show that the CSM predicts Upsilon cross-section ratios in agreement with the most recent LHC data. I then briefly discuss the nuclear-matter effects on Upsilon production at RHIC and the LHC in p(d)A collisions and, by extension, in AA collisions. I argue that a) the Upsilon break-up probability can be neglected, at RHIC and the LHC, b) gluon shadowing --although non-negligible-- is not strong enough to describe forward RHIC data, c) backward RHIC data hints at a gluon EMC effect, possibly stronger than the quark one. Outlooks for the LHC pPb run are also presented.Comment: Contribution to the 5th International Conference On Hard And Electromagnetic Probes Of High-Energy Nuclear Collisions (HP2012), 27 May - 1 June 2012, Cagliari, Italy. 4 pages, 5 figures, LaTeX, uses ecrc.sty (included). v2: version to appear in Nucl. Phys. A (A few typos corrected, 2 refs. added and fig. 1(a) updated with the new STAR point

Cold nuclear matter effects on J/psi production: intrinsic and extrinsic transverse momentum effects

Cold nuclear matter effects on J/psi production in proton-nucleus and nucleus-nucleus collisions are evaluated taking into account the specific J/psi production kinematics at the partonic level, the shadowing of the initial parton distributions and the absorption in the nuclear matter. We consider two different parton processes for the c-cbar pair production: one with collinear gluons and a recoiling gluon in the final state and the other with initial gluons carrying intrinsic transverse momentum. Our results are compared to RHIC observables. The smaller values of the nuclear modification factor R_AA in the forward rapidity region (with respect to the mid rapidity region) are partially explained, therefore potentially reducing the need for recombination effects.Comment: 7 pages, 11 figures, LaTeX, uses elsarticle.cls (included).v2: version (with minor text revisions and Fig 2 and 4a modified) to appear in Phys.Lett.

On the mechanisms of heavy-quarkonium hadroproduction

We discuss the various mechanisms potentially at work in hadroproduction of heavy quarkonia in the light of computations of higher-order QCD corrections both in the Colour-Singlet (CS) and Colour-Octet (CO) channels and the inclusion of the contribution arising from the s-channel cut in the CS channel. We also discuss new observables meant to better discriminate between these different mechanisms.Comment: Invited review talk at 3rd International Conference On Hard And Electromagnetic Probes Of High-Energy Nuclear Collisions (HP2008), 8-14 June 2008, Illa da Toxa, Galicia, Spain. 11 pages, 21 figures, LaTeX, uses svjour.cls and svepj.clo (included

Coexistence of Single and Double-Quantum Vortex Lines

We discuss the configurations in which singly and doubly quantized vortex lines may coexist in a rotating superfluid. General principles of energy minimization lead to the conclusion that in equilibrium the two vortex species segregate within a cylindrical vortex cluster in two coaxial domains where the singly quantized lines are in the outer annular region. This is confirmed with simulation calculations on discrete vortex lines. Experimentally the coexistence can be studied in rotating superfluid $^3$He-A. With cw NMR techniques we find the radial distribution of the two vortex species to depend on how the cluster is prepared: (i) By cooling through $T_c$ in rotation, coexistence in the minimum energy configuration is confirmed. (ii) A glassy agglomerate is formed if one starts with an equilibrium cluster of single-quantum vortex lines and adds to it sequentially double-quantum lines, by increasing the rotation velocity in the superfluid state. This proves that the energy barriers, which separate different cluster configurations, are too high for metastabilities to anneal.Comment: 12 pages, 11 figures; Changed content, 15 pages, 14 figure

Digital play and the actualisation of the consumer imagination

In this article, the authors consider emerging consumer practices in digital virtual spaces. Building on constructions of consumer behavior as both a sense-making activity and a resource for the construction of daydreams, as well as anthropological readings of performance, the authors speculate that many performances during digital play are products of consumer fantasy. The authors develop an interpretation of the relationship between the real and the virtual that is better equipped to understand the movement between consumer daydreams and those practices actualized in the material and now also in digital virtual reality. The authors argue that digital virtual performances present opportunities for liminoid transformations through inversions, speculations, and playfulness acted out in aesthetic dramas. To illustrate, the authors consider specific examples of the theatrical productions available to consumers in digital spaces, highlighting the consumer imagination that feeds them, the performances they produce, and the potential for transformation in consumer-players