Defect CFTs and holographic multiverse

We investigate some aspects of a recent proposal for a holographic description of the multiverse. Specifically, we focus on the implications on the suggested duality of the fluctuations of a bubble separating two universes with different cosmological constants. We do so by considering a similar problem in a 2+1 CFT with a codimension one defect, obtained by an M5-brane probe embedding in AdS_4x S^7, and studying its spectrum of fluctuations. Our results suggest that the kind of behavior required by the spectrum of bubble fluctuations is not likely to take place in defect CFTs with an AdS dual, although it might be possible if the defect supports a non-unitary theory.Comment: 19 pages; v2: typos fixed, minor changes

Thermal Giant Graviton with Non-commutative Dipole Field

Using the type II near-extremal 3D-branes solution we apply the T-duality and smeared twist to construct the supergravity backgrounds which dual to the 4D finite temperature non-commutative dipole field theories. We first consider the zero-temperature system in which, depending on the property of dipole vectors it may be N=2, N=1 or N=0 theory. We investigate the rotating D3-brane configurations moving on the spactimes and show that, for the cases of N=2 and N =1 the rotating D3-brane could be blowed up to the stable spherical configuration which is called as giant graviton and has a less energy than the point-like graviton. The giant graviton configuration is stable only if its angular momentum was less than a critical value of $P_c$ which is an increasing function of the dipole strength. For the case of non-supersymmetric theory, however, the spherical configuration has a larger energy than the point-like graviton. We also find that the dipole field always render the dual giant graviton to be more stable than the point-like graviton. The relation of dual giant graviton energy with its angular momentum, which in the AdS/CFT correspondence being the operator anomalous dimension is obtained. We furthermore show that the temperature does not change the property of the giant graviton, while it will render the dual giant graviton to be unstable.Comment: Latex 20 pages, add comments about BPS bound below (3.8

Shot noise of large charge quanta in superconductor/semiconductor/superconductor junctions

We have found experimentally that the noise of ballistic electron transport in a superconductor/semiconductor/superconductor junction is enhanced relative to the value given by the general relation, S_V=2eIR^2coth(eV/2kT), for two voltage regions in which this expression reduces to its thermal and shot noise limits. The noise enhancement is explained by the presence of large charge quanta, with effective charge q*=(1+2Delta/eV)e, that generate a noise spectrum S_V=2q*IR^2, as predicted in Phys. Rev. Lett. 76, 3814 (1996). These charge quanta result from multiple Andreev reflections at each junction interface, which are also responsible for the subharmonic gap structure observed in the voltage dependence of the junction's conductance.Comment: 5 pages, 5 figures, submitted to Physical Review B as a Rapid Communication. v2 author name in reference corrected. v3 added references. v4 clarifications in the text and reference added thanks to C. Urbin

Page charge of D-branes and its behavior in topologically nontrivial B-fields

The RR Page charges for the D(2p+1)-branes with B-field in type IIB supergravity are constructed consistently from brane source currents. The resulting Page charges are B-independent in the nontrivial and intricate way. It is found that in topologically trivial B-field the Page charge is conserved, but in the topologically nontrivial B-field it is no longer to be conserved, instead there is a jump between two Page charges defined in each patch, and we interpret this jump as Hanany-Witten effect.Comment: 25 pages, 4 figures, typos corrected and reference adde

GSK3β inhibition and canonical Wnt signaling in mice hearts after myocardial ischemic damage

Altres ajuts: This work was supported by the Ministerio de Ciencia e Innovación (to LB); the Instituto de Salud Carlos III (to LB and to MBP); the Generalitat of Catalunya-Secretaria d'Universitats i Recerca del Departament d'Economia i Coneixement de la Generalitat (to LB); the Fundacion Investigación Cardiovascular to LB, and the Spanish Society of Cardiology (SEC2015 to MBP).Aims Myocardial infarction induces myocardial injury and tissue damage. During myocardial infarction strong cellular response is initiated to salvage the damaged tissues. This response is associated with the induction of different signaling pathways. Of these, the canonical Wnt signaling is increasingly important for its prosurvival cellular role, making it a good candidate for the search of new molecular targets to develop therapies to prevent heart failure in infarcted patients. Methods Herein we report that GSK3β regulates the canonical Wnt signaling in C57Bl6 mice hearts. GSK3β is a canonical Wnt pathway inhibitor. Using GSK3β inhibitors and inducing myocardial injury (MI) in Lrp5 mice model we show that GSK3β phosphorylation levels regulate downstream canonical Wnt pathway genes in the ischemic heart. In the setting of MI, myocardial damage assessment usually correlates with functional and clinical outcomes. Therefore, we measured myocardial injury size in Wt and Lrp5 mice in the presence and absence of two different GSK3 inhibitors prior to MI. Myocardial injury was independent of GSK3 inhibitor treatments and GSK3β expression levels. Results These studies support a central role for GSK3β in the activation of the canonical Wnt pathway in the Wt heart. Although LRP5 is protective against myocardial injury, GSK3β expression levels do not regulate heart damage

Correlator of Fundamental and Anti-symmetric Wilson Loops in AdS/CFT Correspondence

We study the two circular Wilson loop correlator in which one is of anti-symmetric representation, while the other is of fundamental representation in 4-dimensional ${\cal N}=4$ super Yang-Mills theory. This correlator has a good AdS dual, which is a system of a D5-brane and a fundamental string. We calculated the on-shell action of the string, and clarified the Gross-Ooguri transition in this correlator. Some limiting cases are also examined.Comment: 22 pages, 5 figures, v2: typos corrected, v3: final version in JHE

Adventures in Holographic Dimer Models

We abstract the essential features of holographic dimer models, and develop several new applications of these models. First, semi-holographically coupling free band fermions to holographic dimers, we uncover novel phase transitions between conventional Fermi liquids and non-Fermi liquids, accompanied by a change in the structure of the Fermi surface. Second, we make dimer vibrations propagate through the whole crystal by way of double trace deformations, obtaining nontrivial band structure. In a simple toy model, the topology of the band structure experiences an interesting reorganization as we vary the strength of the double trace deformations. Finally, we develop tools that would allow one to build, in a bottom-up fashion, a holographic avatar of the Hubbard model.Comment: 22 pages, 8 figures; v2: brief description of case of pure D5 lattice added in sec.3; v3: minor typo fixed; v4: minor change

On the M-theory description of supersymmetric gluodynamics

We study the stringy description of N=1 supersymmetric SU(N) gauge theory on R^{1,2} X S^1. Our description is based on the known Klebanov-Strassler and Maldacena-Nunez solutions, properly modified to account for the compact dimension. The presence of this circle turns out to be a non trivial modification and it leads us to consider the up-lifted eleven dimensional solution. We discuss some of its properties. Perhaps the most interesting one is that extra BPS M-branes are present. These generate a non-perturbative superpotential that we explicitly compute. Our findings, besides their interest in the gauge-string correspondence, may also have applications in the cosmological KKLT and KKLMMT scenarios.Comment: 24 pages; typos corrected and references adde

Atmospheric pressure gas chromatography-time-of-flight-mass spectrometry (APGC-ToF-MS) for the determination of regulated and emerging contaminants in aqueous samples after stir bar sorptive extraction (SBSE)

This work presents the development, optimization and validation of a multi-residue method for the simultaneous determination of 102 contaminants, including fragrances, UV filters, repellents, endocrine disruptors, biocides, polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and several types of pesticides in aqueous matrices. Water samples were processed using stir bar sorptive extraction (SBSE) after the optimization of several parameters: agitation time, ionic strength, presence of organic modifiers, pH, and volume of the derivatizing agent. Target compounds were extracted from the bars by liquid desorption (LD). Separation, identification and quantification of analytes were carried out by gas chromatography (GC) coupled to time-of-flight (ToF-MS) mass spectrometry. A new ionization source, atmospheric pressure gas chromatography (APGC), was tested. The optimized protocol showed acceptable recovery percentages (50–100%) and limits of detection below 1 ng L−1 for most of the compounds. Occurrence of 21 out of 102 analytes was confirmed in several environmental aquatic matrices, including seawater, sewage effluent, river water and groundwater. Non-target compounds such as organophosphorus flame retardants were also identified in real samples by accurate mass measurement of their molecular ions using GC-APGC–ToF-MS. To the best of our knowledge, this is the first time that this technique has been applied for the analysis of contaminants in aquatic systems. By employing lower energy than the more widely used electron impact ionization (EI), AGPC provides significant advantages over EI for those substances very susceptible to high fragmentation (e.g., fragrances, pyrethroids)