3,166 research outputs found

    The Home Economics Teacher in Virginia: Her Training and Experience

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    Selective inhibition of phosphodiesterases 4, 5 and 9 induces HSP20 phosphorylation and attenuates amyloid beta 1-42 mediated cytotoxicity

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    Phosphodiesterase (PDE) inhibitors are currently under evaluation as agents that may facilitate the improvement of cognitive impairment associated with Alzheimer's disease. Our aim was to determine whether inhibitors of PDEs 4,5 and 9 could alleviate the cytotoxic effects of amyloid beta 1–42 (Aβ1-42) via a mechanism involving the small heatshock protein HSP20. We show that inhibition of PDEs 4,5 and 9 but not 3 induces the phosphorylation of HSP20 which, in turn, increases the co-localisation between the chaperone and Aβ1-42 to significantly decrease the toxic effect of the peptide. We conclude that inhibition of PDE9 is most effective to combat Aβ1-42 cytotoxicity in our cell model

    New perspectives on language and gender: Linguistic prescription and compliance in call centres

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    Despite a shift to service-based economies, male-dominated, high-status workplaces have been the predominant focus of research into language and gender in the workplace. This study redresses this shortcoming by considering one female-dominated, low-status, highly regimented workplace that is emblematic of the globalized service economy: call centres. Drawing on 187 call centre service interactions, institutional documents, interviews, and observations from call centres in two national contexts, the study employs an innovative combination of quantitative and qualitative discourse-analytic techniques to compare rule compliance of male and female workers. Female agents in both national contexts are found to comply more with the linguistic prescriptions despite managers and agents emphatically denying the relevance of gender. The study offers a new perspective on language and gender, pointing to the need to expand the methodologies and theories currently favoured to understand how language perpetuates occupational segregation in twenty-first-century workplaces

    Euclidean simplices generating discrete reflection groups

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    Let PP be a convex polytope in the Euclidean space \E^n. Consider the group GPG_P generated by reflections in the facets of PP. We say that PP {\it generates a reflection group GPG_P}. In the present paper, we list all Euclidean simplices generating discrete reflection groups.Comment: 20 pages; MPIM preprin

    Latino and Non-Latino Perceptions of the Air Quality in California's San Joaquin Valley.

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    The San Joaquin Valley (SJV) of California has poor air quality, high rates of asthma, and high rates of obesity. Informational campaigns aimed at increasing awareness of the health impacts of poor air quality and promoting behavior change need to be tailored to the specific target audiences. The study examined perceptions of air quality, perceived health impacts, and methods of accessing information about air quality between Latinos and other groups in the SJV. Residents of the SJV (n = 744) where surveyed via one of three methods: community organizations (256), public locations (251), and an internet panel (237). The results suggest that people perceive the air quality in their region to be generally unhealthy, particularly for sensitive groups. The air quality is more likely to be reported as being unhealthy by people with health problems and less unhealthy by Latinos and people who report regularly exercising. Latinos are more likely to report working outdoors regularly, but also more likely to report being able to reduce their exposure if the air quality is unhealthy. The results report differences in informational sources about air quality, suggesting that informational campaigns should target high risk groups using a variety of media

    Understanding Public Views about Air Quality and Air Pollution Sources in the San Joaquin Valley, California.

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    The San Joaquin Valley of California has poor air quality and high rates of asthma. Surveys were collected from 744 residents of the San Joaquin Valley from November 2014 to January 2015 to examine the public's views about air quality. The results of this study suggest that participants exposed to high PM2.5 (particulate matter less than 2.5 microns in size) concentrations perceived air pollution to be of the worst quality. Air quality in the San Joaquin Valley was primarily perceived as either moderate or unhealthy for sensitive groups. Females perceived air pollution to be of worse quality compared to males. Participants perceived unemployment, crime, and obesity to be the top three most serious community problems in the San Joaquin Valley. Participants viewed cars and trucks, windblown dust, and factories as the principle contributors to air pollution in the area. There is a need to continue studying public perceptions of air quality in the San Joaquin Valley with a more robust survey with more participants over several years and seasons

    Qualitative Indicators of Social Resilience in Small-Scale Fishing Communities: An Emphasis on Perceptions and Practice

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    This paper reports on ethnographic research aimed at understanding what resilience means to those living within fishery-dependent communities. We draw on semi-structured and oral history interviews, focus groups, and household and business interviews in four Maine fishing communities to examine the reflections of fishermen and other community members on the past, present, and future of their communities, including the threats they face and how they are able to respond to them. Based on our analysis, we identify broad qualitative indicators of resilience: survival, social identity, diversification, getting by, and optimism. The indicators of resilience that we identify are difficult to fully understand using secondary data and, therefore, we argue that understanding them also requires an ethnographic research approach that focuses on the practices of fishermen and the context in which those fishermen live
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