The Effect Of A Medical Decompression Protocol On The Use Of Antiemetics, Nasogastric Tube Usage And Diet Advance In Late Stage Cancer Patients With Functional Intestinal Obstruction

At the end of life, many patients suffer from a syndrome that simulates classic small bowel obstruction. The traditional approach to intestinal obstruction is relief of pressure in the gastrointestinal tract using mechanical methods such as naso-gastric tube insertion and suctioning. This relieves the distension of the hollow organs and thus the nausea.. Pharmacologic methods are also used in the care of these patients, however, there is debate as to which agents to use and when to use them. The Medical Decompression protocol is a non-invasive pharmacologic approach to this problem. It brings with it ease and economy of delivery, the ability to administer it in intravenous as well as oral form, and is a multi-agent protocol of tried and true drugs used at the end of life: 1/2 Metoclopramide, Dexamethasone, Diphenhydramine, and Pantoprazole Prior to initiating this intervention, patients and their families are educated and are aware that this intervention is most likely a temporary measure aimed at symptom relief, as well as an attempt to improve quality of life. Our sample contained 42 males and 62 females, with an average age of about 70 years. About 51% of participants received MD (n = 53). Results indicated that there was a statistically significant difference between the two groups related to days to progress diet. We propose that a pharmacologic method such as MD is strongly considered as first line treatments for the functional intestinal obstruction syndrome and indeed be considered as adjuncts to allow the removal of invasive mechanical interventions in the end of life patient

Permanent genetic resources added to Molecular Ecology Resources Database 1 October 2010-30 November 2010

This article documents the addition of 277 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Ascochyta rabiei, Cambarellus chapalanus, Chionodraco hamatus, Coptis omeiensis, Cynoscion nebulosus, Daphnia magna, Gerbillus nigeriae, Isurus oxyrinchus, Lates calcarifer, Metacarcinus magister, Oplegnathus fasciatus, Pachycondyla verenae, Phaethon lepturus, Pimelodus grosskopfii, Rotylenchulus reniformis, Scomberomorus niphonius, Sepia esculenta, Terapon jarbua, Teratosphaeria cryptica and Thunnus obesus. These loci were cross-tested on the following species: Austropotamobius italicus, Cambarellus montezumae, Cambarellus puer, Cambarellus shufeldtii, Cambarellus texanus, Chionodraco myersi, Chionodraco rastrospinosus, Coptis chinensis, Coptis chinensis var. brevisepala, Coptis deltoidea, Coptis teeta, Orconectes virilis, Pacifastacus leniusculus, Pimelodus bochii, Procambarus clarkii, Pseudopimelodus bufonius, Rhamdia quelen, Sepia andreana, Sepiella maindroni, Thunnus alalunga, Thunnus albacares, Thunnus maccoyii, Thunnus orientalis, Thunnus thynnus and Thunnus tonggol