13,137 research outputs found

    Whales, dolphins, and porpoises of the western North Atlantic: a guide to their identification

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    This is an identification guide for cetaceans (whales, dolphins, and porpoises). It was designed to assist laypersons in identifying cetaceans encountered in the western North Atlantic Ocean and was intended for use by ongoing cetacean observer programs. This publication includes sections on identifying cetaceans at sea as well as stranded animals on shore. Species accounts are divided by body size and presence or lack of a dorsal fin. Appendices cover tags used on cetacean species; how to record and report cetacean observations at see and for stranded cetaceans; and a list of contacts for reporting cetacean strandings. (Document pdf contains 183 pages - file takes considerable time to open

    Modern Logic and Judicial Decision Making: A Sketch of One View

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    Two hundred years elapsed before the nineteenth century logicians Boole, De Morgan, and others, finally succeeded in formally developing the calculus of reason-ing first suggested by the German mathematician, Leibniz. It is, perhaps, to the credit of the legal profession that less than one century has subsequently elapsed, and already some lawyers and legal writers, along with other scholars, are beginning to explore the relationship between modern logic and law. What is attempted here is to outline the bare bones of one tentative way of looking at the relationship between modern logic and the judicial decision process. From the useful vantage point of a Lasswellian social process framework of analysis, logic and judicial decision making are considered contextually within that total mani-fold of events that we call the world. Thus viewed, the judicial decision making process is just one constituent of the complex unfolding of events through time. We attempt to represent some of the complexities involved in each of these processes and the relationships between them by means of a series of diagrams. By suggesting that we begin with the world as our context, we make no claim to describing it in complete detail. To the contrary, the sketch presented here-we would emphasize the word sketch and the word tentative -is rough, incomplete, and subject to considerable improvement. But one of our purposes will be served if the outline points the way toward cumulative efforts to achieve a comprehensive description of the judicial decision process. In addition to this broad look at logic, judicial decision making, and the world, a more modest aim is to describe, in some detail and with reasonable clarity, one aspect of the relation between logic and judicial decision making

    Physics case of the very high energy electron--proton collider, VHEeP

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    The possibility of a very high energy electron-proton (VHEeP) collider with a centre-of-mass energy of 9 TeV has been presented at previous workshops. These proceedings briefly summarise the VHEeP concept, which was recently published, and developments since then, as well as future directions. At the VHEeP collider, with a centre-of-mass energy 30 times greater than HERA, parton momentum fractions, xx, down to about 10−810^{-8} are accessible for photon virtualities, Q2Q^2, of 1 GeV2^2. This extension in the kinematic range to low xx complements proposals for other electron-proton or electron-ion colliders.Comment: 6 pages, 2 figures, for proceedings of DIS 2017 worksho

    Tropidosteptes forestierae (Hemiptera: Heteroptera: Miridae: Mirinae): a new species of Plant Bug injuring ornamental Florida Swampprivet, Forestiera segregata (Oleaceae), in South Florida

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    The mirine plant bug Tropidosteptes forestierae, new species (Hemiptera: Miridae) is described from Collier County, Florida, where it was found causing serious injury to an extensive ornamental hedge of Florida swampprivet, Forestiera segregata (Jacq.) Krug and Urb. (Oleaceae). Adult male and female, fifth instar, and egg are described. Color images of the adults, nymph, egg, and injury; scanning photomicrographs of selected adult structures; and illustrations of male genitalia are provided. A key to help distinguish the 16 species of Tropidosteptes known to occur in the southeastern United States is given

    Using a Primordial Gravitational Wave Background to Illuminate New Physics

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    A primordial spectrum of gravitational waves serves as a backlight to the relativistic degrees of freedom of the cosmological fluid. Any change in the particle physics content, due to a change of phase or freeze-out of a species, will leave a characteristic imprint on an otherwise featureless primordial spectrum of gravitational waves and indicate its early-Universe provenance. We show that a gravitational wave detector such as the Laser Interferometer Space Antenna would be sensitive to physics near 100 TeV in the presence of a sufficiently strong primordial spectrum. Such a detection could complement searches at newly proposed 100 km circumference accelerators such as the Future Circular Collider at CERN and the Super Proton-Proton Collider in China, thereby providing insight into a host of beyond Standard Model issues, including the hierarchy problem, dark matter, and baryogenesis.Comment: 7 pages, 3 figures; added reference

    The calculative nature of microbial biofilms and bioaggregates

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    Biological proliferation isopt imized at variouslevels of organization, including the molecule (e.g. nucleic acids, prions), the cell (e.g. prokaryotic cells, eukaryotic cells), and the community (e.g. microbial biofilms, bioaggregates). Although it was initially assumed that this occurred through the genesis of information within DNA alone, it now appearsthat innovative design originates at other levels of organization in addition to DNA. For example, the recombination of community structures affects the proliferation rate of genetic structures; and the recombination of genetic structures affects the proliferation rate of community structures. This feedback mechanism computes compromises between the form and function of both community and nucleic acid. A nested series of proliferating objects (e.g. genetic structure, cell structure, community structure) is thus capable of continually updating the form of each object in the series. This accounts for the calculative nature of prokaryotic cells, eukaryotic cells, biofilms, bioaggregates, microbial consortia, and most other complex adaptive systems

    The Dwarf Spheroidal Companions to M31: WFPC2 Observations of Andromeda I

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    Images have been obtained with the Hubble Space Telescope WFPC2 camera of Andromeda I, a dwarf spheroidal (dSph) galaxy that lies in the outer halo of M31. The resulting color-magnitude diagrams reveal for the first time the morphology of the horizontal branch in this system. We find that, in a similar fashion to many of the galactic dSph companions, the horizontal branch (HB) of And~I is predominantly red. Combined with the metal abundance of this dSph, this red HB morphology indicates that And I can be classified as a ``second parameter'' system in the outer halo of M31. This result then supports the hypothesis that the outer halo of M31 formed in the same extended chaotic manner as is postulated for the outer halo of the Galaxy.Comment: 26 pages using aas2pp4.sty, including 2 tables and 7 figures, to be published in AJ. Figure 1 is in gif form. To include in main ps file, use xv to create a ps file called Da_Costa.fig1.ps and uncomment appropriate lines in .tex fil

    Dihydropyrimidine-thiones and clioquinol synergize to target beta-amyloid cellular pathologies through a metal-dependent mechanism

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    The lack of therapies for neurodegenerative diseases arises from our incomplete understanding of their underlying cellular toxicities and the limited number of predictive model systems. It is critical that we develop approaches to identify novel targets and lead compounds. Here, a phenotypic screen of yeast proteinopathy models identified dihydropyrimidine-thiones (DHPM-thiones) that selectively rescued the toxicity caused by β-amyloid (Aβ), the peptide implicated in Alzheimer’s disease. Rescue of Aβ toxicity by DHPM-thiones occurred through a metal-dependent mechanism of action. The bioactivity was distinct, however, from that of the 8-hydroxyquinoline clioquinol (CQ). These structurally dissimilar compounds strongly synergized at concentrations otherwise not competent to reduce toxicity. Cotreatment ameliorated Aβ toxicity by reducing Aβ levels and restoring functional vesicle trafficking. Notably, these low doses significantly reduced deleterious off-target effects caused by CQ on mitochondria at higher concentrations. Both single and combinatorial treatments also reduced death of neurons expressing Aβ in a nematode, indicating that DHPM-thiones target a conserved protective mechanism. Furthermore, this conserved activity suggests that expression of the Aβ peptide causes similar cellular pathologies from yeast to neurons. Our identification of a new cytoprotective scaffold that requires metal-binding underscores the critical role of metal phenomenology in mediating Aβ toxicity. Additionally, our findings demonstrate the valuable potential of synergistic compounds to enhance on-target activities, while mitigating deleterious off-target effects. The identification and prosecution of synergistic compounds could prove useful for developing AD therapeutics where combination therapies may be required to antagonize diverse pathologies.D.F.T was funded by NRSA Fellowship NIH 5F32NS061419. D.F.T. and S.L. were supported by WIBR funds in support of research on Regenerative Disease, the Picower/JPB Foundation, and the Edward N. and Della L. Thome Foundation. G.A.C. and S.L. were funded by a Howard Hughes Medical Institute (HHMI) Collaborative Innovation Award. L.E.B., R.T., and S.E.S. were funded by NIH GM086180, NIH GM067041, and NIH GM111625. (5F32NS061419 - NRSA Fellowship NIH; WIBR funds in support of research on Regenerative Disease; Picower/JPB Foundation; Edward N. and Della L. Thome Foundation; Howard Hughes Medical Institute (HHMI) Collaborative Innovation Award; GM086180 - NIH; NIH GM067041 - NIH; NIH GM111625 - NIH)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705239/Accepted manuscrip

    Eating Disorder Symptoms, Body Image Attitudes, and Risk Factors in Non-Traditional and Traditional Age Female College Students.

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    This study investigates whether there are certain age groups in college that are more susceptible to eating problems and the contributing factors for eating disorders. The participants were 144 college women divided into traditional and non-traditional age groups. The EDI-2, BSI, RSE, and additional items were administered. The results show that non-traditional age college women were as likely to have eating disorder symptoms and more likely to possess body dissatisfaction than traditional age college students. The data support body dissatisfaction, aging concerns, perfectionism, depression, anxiety, and having children as potential risk factors for eating disturbances. This study suggests that there are high prevalence rates of eating disturbances in all college female age groups, but that the highest prevalence may actually be in older women. It is imperative that clinicians and others working in colleges realize these issues can affect students of all ages
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