2,973 research outputs found

    Temperature effects on the magnetization of quasi-one-dimensional Peierls distorted materials

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    It is shown that temperature acts to disrupt the magnetization of Peierls distorted quasi-one-dimensional materials (Q1DM). The mean-field finite temperature phase diagram for the field theory model employed is obtained by considering both homogeneous and inhomogeneous condensates. The tricritical points of the second order transition lines of the gap parameter and magnetization are explicitly calculated. It is also shown that in the absence of an external static magnetic field the magnetization is always zero, at any temperature. As expected, temperature does not induce any magnetization effect on Peierls distorted Q1DM.Comment: 11 pages, 2 figure

    Sensitive Dependence on Parameters of Continuous-time Nonlinear Dynamical Systems

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    We would like to thank the partial support of this work by the Brazilian agencies FAPESP (processes: 2011/19296-1 and 2013/26598-0, CNPq and CAPES. MSB acknowledges EPSRC Ref. EP/I032606/1.Peer reviewedPostprin

    Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer.

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    The cancer stem cell hypothesis, that a small population of tumour cells are responsible for tumorigenesis and cancer progression, is becoming widely accepted and recent evidence has suggested a prognostic and predictive role for such cells. Intra-tumour heterogeneity, the diversity of the cancer cell population within the tumour of an individual patient, is related to cancer stem cells and is also considered a potential prognostic indicator in oncology. The measurement of cancer stem cell abundance and intra-tumour heterogeneity in a clinically relevant manner however, currently presents a challenge. Here we propose signalling entropy, a measure of signalling pathway promiscuity derived from a sample's genome-wide gene expression profile, as an estimate of the stemness of a tumour sample. By considering over 500 mixtures of diverse cellular expression profiles, we reveal that signalling entropy also associates with intra-tumour heterogeneity. By analysing 3668 breast cancer and 1692 lung adenocarcinoma samples, we further demonstrate that signalling entropy correlates negatively with survival, outperforming leading clinical gene expression based prognostic tools. Signalling entropy is found to be a general prognostic measure, valid in different breast cancer clinical subgroups, as well as within stage I lung adenocarcinoma. We find that its prognostic power is driven by genes involved in cancer stem cells and treatment resistance. In summary, by approximating both stemness and intra-tumour heterogeneity, signalling entropy provides a powerful prognostic measure across different epithelial cancers

    Symmetry Nonrestoration in a Resummed Renormalized Theory at High Temperature

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    We reinvestigate the interesting phenomenon of symmetry nonrestoration at high temperature in the multifield O(N_1) X O(N_2) model. We apply modified self-consistent resummation (MSCR) in order to obtain the scalar dressed masses and find in what circumstances a resummed multifield theory which has symmetry (non)restoration can be renormalized. It is shown that, aside from the consistency of the MSCR method, the basic ingredient that guarantees the renormalization of a multifield model within a resummation approach is the T^2 mass behavior of field theory at high temperature.Comment: 14 pages, 1 ps figure, revtex, Phys. Rev. D versio

    Trapping Phenomenon Attenuates the Consequences of Tipping Points for Limit Cycles

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    We would like to thank the partial support of this work by the Brazilian agencies FAPESP (processes: 2011/19296-1, 2013/26598-0, and 2015/20407-3), CNPq and CAPES. MSB acknowledges EPSRC Ref. EP/I032606/1.Peer reviewedPublisher PD

    Experimental observation of a complex periodic window

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    The existence of a special periodic window in the two-dimensional parameter space of an experimental Chua's circuit is reported. One of the main reasons that makes such a window special is that the observation of one implies that other similar periodic windows must exist for other parameter values. However, such a window has never been experimentally observed, since its size in parameter space decreases exponentially with the period of the periodic attractor. This property imposes clear limitations for its experimental detection.Comment: 4.2 pages, 4 figure

    Torsion-Adding and Asymptotic Winding Number for Periodic Window Sequences

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    In parameter space of nonlinear dynamical systems, windows of periodic states are aligned following routes of period-adding configuring periodic window sequences. In state space of driven nonlinear oscillators, we determine the torsion associated with the periodic states and identify regions of uniform torsion in the window sequences. Moreover, we find that the measured of torsion differs by a constant between successive windows in periodic window sequences. We call this phenomenon as torsion-adding. Finally, combining the torsion and the period adding rules, we deduce a general rule to obtain the asymptotic winding number in the accumulation limit of such periodic window sequences
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