Technology and connection in the deaf world

Thesis (S.M. in Science Writing)--Massachusetts Institute of Technology, Dept. of Humanities, Graduate Program in Science Writing, 2010.Cataloged from PDF version of thesis.Includes bibliographical references (p. 27-30).In 1984, the FDA approved a medical device called a cochlear implant for adult use in the United States. Unlike assistive hearing technologies that came before it, such as hearing aids, cochlear implants could offer wider access to sound even to the profoundly deaf. Given adult success with the device, the FDA lowered in 1990 the required age for implantation to two years old. The following year the National Association of the Deaf published a position statement on cochlear implants comparing them to "cultural genocide." This thesis explores two parallel stories. Drawing on interviews with implant engineers, surgeons, audiologists, and other specialists, the piece describes how cochlear implants function and how the devices have improved since the 1980s. Equally, the thesis pulls from interviews with bioethicists, deaf and hard of hearing individuals, educators at a signing deaf school, and others in the deaf community to describe the unique attributes and history of deaf culture and the changing and diverse reactions of the deaf community to this medical device.by Joseph Benjamin Calamia.S.M.in Science Writin

Immigrazione, Diritto e Diritti: profili internazionalistici ed europei

Il Volume ha la duplice valenza di testo universitario e di testo di riferimento per gli studiosi che vogliono costruirsi una competenza utile in enti internazionali o nazionali, per i professionisti del diritto (in particolare, avvocati e magistrati), per gli operatori delle ONG nonché delle forze dell’ordine e degli altri enti pubblici chiamati a governare i fenomeni migratori. Nella prima parte, sono state affrontate alcune questioni generali, che mostrano come sia venuta evolvendosi la cooperazione internazionale in materia e il diritto che ne è il frutto, e come siano progressivamente sorti differenti status che arricchiscono e complicano il quadro d’analisi. Nella seconda parte sono stati analizzati i profili concernenti l’uscita dal territorio e il ritorno, il controllo delle frontiere, l’ingresso in uno Stato che non è il proprio. Una costante attenzione è dedicata all’ampia normativa elaborata dall’UE. La terza parte affronta il tema del trattamento dello straniero ammesso sul territorio: un capitolo di inquadramento generale è affiancato da alcuni studi tematici, inerenti alla sfera dei rapporti sociali ed economici, all’istruzione e ai titoli di studio e professionali, alla partecipazione alla vita politica e ai processi elettorali. La quarta parte affronta le complesse questioni poste dalle diverse forme di allontanamento, lette anche in relazione alla tutela dei diritti umani. Infine, la quinta parte tratta questioni che non avrebbero potuto trovare agevole collocazione nelle altre parti (l’unità familiare, le varie forme di cooperazione tra Stati in tema di migrazioni, la Convenzione ONU del 1990 sui lavoratori migranti)

Análisis comparativo de células madre mesenquimales procedentes de pacientes artrósicos y sanos en diferenciación condrogénica

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Isolated Metachronous Splenic Metastasis from Colon Cancer: Possible Explanations for This Rare Entity

The incidence of splenic metastases secondary to colorectal cancer is very low; these lesions have been more frequently reported as secondary to breast, lung, and ovarian cancer. Splenic metastases are particularly common in melanoma; their incidence has been reported as being as high as 34% at autopsy [1]. Most cases of secondary splenic metastases have been described in patients with tumors of the left colon while only few cases being reported as originating from right colon tumors (Table 1). The finding of a splenic mass in the absence of a history of malignancy suggests a primary lesion (lymphoma, hematoma, etc.), while a history of oncological disease raises the possibility of a secondary lesion [2]

Evaluation of chondroprotective effect of glucosamine and chondroitin sulfate by a proteomic approach

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The addition of simvastatin administration to cold storage solution of explanted whole liver grafts for facing ischemia/reperfusion injury in an area with a low rate of deceased donation: a monocentric randomized controlled double-blinded phase 2 study.

BACKGROUND: Liver transplantation is the best treatment for end-stage liver disease. The interruption of the blood supply to the donor liver during cold storage damages the liver, affecting how well the liver will function after transplant. The drug Simvastatin may help to protect donor livers against this damage and improve outcomes for transplant recipients. The aim of this study is to evaluate the benefits of treating the donor liver with Simvastatin compared with the standard transplant procedure. PATIENT AND METHODS: We propose a prospective, double-blinded, randomized phase 2 study of 2 parallel groups of eligible adult patients. We will compare 3-month, 6-month, and 12-month graft survival after LT, in order to identify a significant relation between the two homogenous groups of LT patients. The two groups only differ by the Simvastatin or placebo administration regimen while following the same procedure, with identical surgical instruments, and medical and nursing skilled staff. To reach these goals, we determined that we needed to recruit 106 patients. This sample size achieves 90% power to detect a difference of 14.6% between the two groups survival using a one-sided binomial test. DISCUSSION: This trial is designed to confirm the effectiveness of Simvastatin to protect healthy and steatotic livers undergoing cold storage and warm reperfusion before transplantation and to evaluate if the addition of Simvastatin translates into improved graft outcomes. TRIAL REGISTRATION: ISRCTN27083228

Cuantificación por SILAC del efecto de la nicotina sobre condrocitos articulares

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Quantitative proteomics analysis of chondrogenic differentiation of mesenchymal stem cells by SILAC

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Proteome analysis during a new chondrogenesis model from mesenchymal stem cells of human umbilical cord stroma

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Búsqueda de biomarcadores séricos de artrosis mediante depleción secuencias combinada con DIGE

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