Lower Mississippian Chert Development, Southern Midcontinent Region

The Lower Mississippian Boone Formation is a chert-bearing, fossiliferous limestone typically 100-115m. thick forming the Springfield Plateau across the tri-state region of northwestern Arkansas, southwestern Missouri, and northeastern Oklahoma. The Boone represents the maximum flooding, highstand, and regressive intervals of a single, third order transgressive-regressive carbonate cycle bounded by regional unconformities. Two types of chert occur in this formation, and provide the basis for subdivision of the Boone into informal lower and upper members in northern Arkansas. The lower Boone represents early Osagean maximum flooding conditions and consists of calcisiltites with interbedded dark, nodular chert. This chert exhibits compaction phenomena and shrinkage fractures, indicating a penecontemporaneous origin from reorganization of silica immediately below the sediment water interface prior to lithification of the carbonate sediments (Manger et al. 1988a). The upper Boone represents late Osagean highstand and regression and consists primarily of carbonate grainstones and packstones (Shelby 1986). This interval contains white, later diagenetic chert, interpreted as a groundwater phenomenon in which silica has replaced lithified carbonate along its bedding planes, replicating the fabric of the limestone (Manger and Shelby 2000). This later diagenetic chert replacement favors the finer grained intervals and replicates the fabric of the limestone being replaced. Previous studies have shown that the penecontemporaneous chert typically comprises 40-50% of the lower Boone interval, while the later diagenetic chert contribution to the upper Boone ranges from 30-95% (Liner 1979). Understanding chert development is unsettled, and has been the subject of debate, primarily involving the source of the silica producing the chert, and the mode of formation of the chert-bearing intervals. Geochemical analyses suggest a volcanic rather than biogenic source for the silica in the Boone Formation

Hydrothermally Emplaced, Lower Mississippian, Tripolitic Chert and Its Possible Relationship to the Tri-State Lead-Zinc Mining District

Across the southern Ozark Region, northern Arkansas, southwestern Missouri, and northeastern Oklahoma, exposures of the Lower Mississippian Boone Formation and its equivalents exhibit well-developed tripolitic chert that has been mined, more or less continuously, for at least 80 years. The tripolitic chert is a replacement of an interval within the basal portion of the upper Boone Formation in Arkansas and Oklahoma, and equivalent to the Elsey Formation in Missouri. The movement of silica-rich, hydrothermal fluids appears to have been much like that of a confined aquifer. It followed the basal upper Boone Formation (Arkansas) = Elsey Formation (Missouri) and was bound below by an impermeable interval at the top of the lower Boone Formation (Arkansas) = Reeds Spring Formation (Missouri), and above by the base of the upper Boone Formation (Arkansas) = Burlington-Keokuk (Missouri). The first hydrothermal event incompletely silicified the basal upper Boone = Elsey Formation. After leaching of the remnant carbonate, thus forming the tripolitic chert, a second hydrothermal event deposited terminated and doubly terminated quartz crystals, and druse in the tripolitic chert voids. This hydrothermal event may have pro-duced the Mississippi Valley-Type (MVT) lead-zinc deposits in northeast Oklahoma and southwestern Missouri. The famous deposits at Picher, Oklahoma, and Joplin, Missouri, appear to be positioned in the apparent path of the hydrothermal fluid migration. While timing of these hydrothermal events is unclear, they may reflect lateral secretion produced by the Ouachita Orogeny in the Late Pennsylvanian

ϕ\phi meson production in sNN\sqrt{s_{NN}} = 200 GeV Au+Au and pp collisions at RHIC

We present the results for the measurement of $\phi$ meson production in $\sqrt{s_{NN}}$ = 200 GeV Au+Au and pp collisions at the Relativistic Heavy Ion Collider (RHIC). Using the event mixing technique, spectra and yields are obtained from the $\phi\to K^{+}K^{-}$ decay channel for different centrality bins in Au+Au collisions and in pp collisions. We observe that the spectrum shape in Au+Au collisions depends weakly on the centrality and the shape of the spectrum in pp collisions is significantly different from that in Au+Au collisions. In Au+Au collisions, the extracted yield of $\phi$ meson is flat as a function of rapidity; The $$ of $\phi$, extracted from the fit function to the spectra, shows a different behavior as a function of centrality than that of $\pi^-$, $K^-$ and $\bar{p}$Comment: Proceedings for the 7th International Conference on Strangeness in Quark Matte

Hodgkin's lymphoma presenting with heart failure: a case report

<p>Abstract</p> <p>Introduction</p> <p>Cardiac involvement in malignant lymphoma is one of the least investigated subjects in oncology. This article reports a case of cardiac involvement in Hodgkin's lymphoma which presented as heart failure.</p> <p>Case presentation</p> <p>We report the case of an 8-year-old Afghan girl with Hodgkin's lymphoma. The disease presented with systemic signs and symptoms, including abdominal distension, weakness, pallor, chills, fever, generalized edema, hepatosplenomegaly and generalized lymphadenopathy, as well as signs of heart failure. Test results showed a rare form of heart metastasis.</p> <p>Conclusion</p> <p>We report a case of Hodgkin's lymphoma with metastasis to the heart, detected premortem. Although the involvement of the heart in a malignancy is relatively common, premortem detection is unusual and only few studies have reported it in the literature.</p

Patterns of adherence to and compliance with the Portuguese smoke-free law in the leisure-hospitality sector

CIEC – Research Centre on Child Studies, UM (FCT R&D 317)Background: In 2008, the Portuguese smoke-free law came into effect including partial bans in the leisure-hospitality (LH) sector. The objective of the study is to assess the prevalence of smoking control policies (total ban, smoking permission and designated smoking areas) adopted by the LH sector in Portugal. The levels of noncompliance with each policy are investigated as well as the main factors associated with smoking permission and noncompliance with the law. Methods: Cross-sectional study conducted between January 2010 and May 2011. A random sample of venues was selected from the Portuguese LH sector database, proportionally stratified according to type, size and geographical area. All venues were assessed in loco by an observer. The independent effects of venues’ characteristics on smoking permission and the level of noncompliance with the law were explored using logistic regression. Results: Overall, 1.412 venues were included. Total ban policy was adopted by 75.9% of venues, while 8.4% had designated smoking areas. Smoking ban was more prevalent in restaurants (85.9%). Only 29.7% of discos/bars/pubs opted for complete ban. Full or partial smoking permission was higher in discos/bar/pubs (OR = 7.37; 95%CI 4.87 to 11.17). Noncompliance with the law was higher in venues allowing smoking and lower in places with complete ban (33.6% and 7.6% respectively, p, 0.001). Discos/bars/pubs with full smoking permission had the highest level of noncompliance (OR = 3.31; 95%CI 1.40 to 7.83). Conclusions: Our findings show a high adherence to smoking ban policy by the Portuguese LH sector. Nonetheless, one quarter of the venues is fully or partially permissive towards smoking, with the discos/bars/pubs considerably contributing to this situation. Venues with smoking permission policies were less compliant with the legislation. The implementation of a comprehensive smoke-free law, without any exceptions, is essential to effectively protect people from the second hand smoke.The work is part of a large Epidemiological Study on the Portuguese Tobacco Control Policy, developed by the Instituto de Medicina Preventiva da Faculdade de Medicina de Lisboa and supported, in its preliminary part, by the Direccao Geral da Saude (DGS) and, in the second part, by the national funding institution Fundacao para a Ciencia e Tecnologia (FCT). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

Defining sepsis on the wards: results of a multi-centre point-prevalence study comparing two sepsis definitions

Our aim was to prospectively determine the predictive capabilities of SEPSIS-1 and SEPSIS-3 definitions in the emergency departments and general wards. Patients with National Early Warning Score (NEWS) of 3 or above and suspected or proven infection were enrolled over a 24-h period in 13 Welsh hospitals. The primary outcome measure was mortality within 30 days. Out of the 5422 patients screened, 431 fulfilled inclusion criteria and 380 (88%) were recruited. Using the SEPSIS-1 definition, 212 patients had sepsis. When using the SEPSIS-3 definitions with Sequential Organ Failure Assessment (SOFA) score ≥ 2, there were 272 septic patients, whereas with quickSOFA score ≥ 2, 50 patients were identified. For the prediction of primary outcome, SEPSIS-1 criteria had a sensitivity (95%CI) of 65% (54–75%) and specificity of 47% (41–53%); SEPSIS-3 criteria had a sensitivity of 86% (76–92%) and specificity of 32% (27–38%). SEPSIS-3 and SEPSIS-1 definitions were associated with a hazard ratio (95%CI) 2.7 (1.5–5.6) and 1.6 (1.3–2.5), respectively. Scoring system discrimination evaluated by receiver operating characteristic curves was highest for Sequential Organ Failure Assessment score (0.69 (95%CI 0.63–0.76)), followed by NEWS (0.58 (0.51–0.66)) (p < 0.001). Systemic inflammatory response syndrome criteria (0.55 (0.49–0.61)) and quickSOFA score (0.56 (0.49–0.64)) could not predict outcome. The SEPSIS-3 definition identified patients with the highest risk. Sequential Organ Failure Assessment score and NEWS were better predictors of poor outcome. The Sequential Organ Failure Assessment score appeared to be the best tool for identifying patients with high risk of death and sepsis-induced organ dysfunction

Lithologic Stratigraphic Position, Sequence and Diagenetic History, Lower Mississippian Tripolitic Chert, Northern Arkansas and Southern Missouri

Tripolitic chert development in the southern Ozark region is associated with a third-order, transgressive-regressive cycle comprising St. Joe transgressive packstones, succeeded by lower Boone calcisiltites, with black, penecontemporaneous, nodular chert deposited during maximum flooding, overlain by basal upper Boone calcisiltites deposited during highstand. The onset of regression produced upper Boone packstones and grainstones with white-gray, later diagenetic chert reflecting groundwater replacement along bedding planes. Tripolitic chert is a product of the highstand calcisiltites at the base of the upper Boone Formation of Arkansas, and its equivalent, the Elsey Formation of southern Missouri. This tripolitic chert appears to reflect a hydrothermal event likely occurring after the emplacement processes of both Boone cherts that had ended by Chesterian time. After hydrothermal silicification, the interval experienced groundwater removal of most of the remaining carbonate leaving open porosity characteristic of tripolitic chert. A second hydrothermal event precipitated terminated and doubly terminated quartz crystals as well as quartz druse in the cavities produced by the earlier carbonate leaching from the tripolitic chert. Timing of the hydrothermal events is not clear, but they may reflect lateral secretion produced by the Ouachita Orogeny in the late Pennsylvanian

SAPHO syndrome associated with hidradenitis suppurativa and pyoderma gangrenosum successfully treated with adalimumab and methotrexate : a case report and review of the literature

SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare inflammatory condition describing the combination of skin, bone, and joint manifestations that has a heterogeneous presentation. We report a case of severe SAPHO syndrome in association with hidradenitis suppurativa and pyoderma gangrenosum in a 27-year-old male. The patient had an initial migratory arthritis affecting the knees, ankles, metacarpophalangeal joints, proximal interphalangeal joints, wrists, shoulder, and lower back, which progressed to a persistent arthritis and swelling at the sternum, shoulders, wrists, hands, feet, and lower back. Radiographic changes were consistent with the diagnosis of SAPHO syndrome. Serum proinflammatory cytokine levels were significantly elevated and improved substantially after 3 months of therapy. Rationale for therapy in this patient was the observation that tumor necrosis alpha antagonists have been successfully used in SAPHO syndrome, and since arthropathy was so prominent in our patient, we elected to use adalimumab combined with methotrexate