Gamma radiation measurements using an optical fiber laser

Trabajo presentado a la 26th International Conference on Optical Fiber Sensors. Suiza, 2020A fiber ring laser cavity configuration was used to analyze the effect of gamma-irradiation over the performance of different types of erbium doped fibers. Preliminary results validates this method to monitor gamma-radiation in real time.Financial support from the Spanish Comisión Interministerial de Ciencia y Tecnología within project TEC2016- 76021-C2-1-R and FEDER funds from the European Union are acknowledged. The reported investigations were performed in the frame of the COST Action MP 1401

Trabajo social con comunidades en el siglo XXI

El texto responde a un propósito eminentemente didáctico. Es producto de la colaboración de varios autores procedentes de las universidades de Murcia, Sonora (México) y la UNED. Los autores resaltan la importancia de la intervención social comunitaria como disciplina y cómo profesión, considerando como objetivo del Trabajo social comunitario recuperar, potenciar y significar las condiciones de vida y la trayectoria personal de los ciudadano

Aproximación a la evaluación de un programa de "formación fuera del aula" en la Universidad

The present time of a world in constant change invites of a special way to the educational ones of any scope, to look for new ways to imply the student. In order to be able to approach I tot the deepest reality of the educative process: to be able to remove the best thing from each one. The present case shows a program that looks for to us, through different activities outside the classroom, to introduce to the college student, not in the paradigms and own lessons of each subject, but in something more general than are in the base of all university education. One is keys like the search of the truth, the synthesis of knowledge's, the integral formation and the service to the society.La actualidad de un mundo en constante cambio invita de una manera especial a los docentes de cualquier ámbito a buscar nuevas maneras de implicar al alumno en su propia formación, para acercarlo a la realidad más profunda del proceso educativo y poder sacar lo mejor de cada uno. El presente estudio nos muestra un programa que busca, a través de diferentes actividades fuera del aula, introducir al universitario, no en los paradigmas y enseñanzas propios de cada asignatura, sino en algo más general que está en la base de toda educación universitaria. Se trata de claves de sentido, como la búsqueda de la verdad, la síntesis de saberes, la formación integral y el servicio a la sociedad

Minimal residual disease evaluation by flow cytometry is a complementary tool to cytogenetics for treatment decisions in acute myeloid leukaemia

For PETHEMA Programa para el Estudio de la Terapéutica en Hemopatías Malignas Cooperative Study Group.The clinical utility of minimal residual disease (MRD) analysis in acute myeloid leukaemia (AML) is not yet defined. We analysed the prognostic impact of MRD level at complete remision after induction therapy using multiparameter flow cytometry in 306 non-APL AML patients. First, we validated the prognostic value of MRD-thresholds we have previously proposed (≥0.1%; ≥0.01-0.1%; and <0.01), with a 5-year RFS of 38%, 50% and 71%, respectively (p = 0.002). Cytogenetics is the most relevant prognosis factor in AML, however intermediate risk cytogenetics represent a grey zone that require other biomarkers for risk stratification, and we show that MRD evaluation discriminate three prognostic subgroups (p = 0.03). Also, MRD assessments yielded relevant information on favourable and adverse cytogenetics, since patients with favourable cytogenetics and high MRD levels have poor prognosis and patients with adverse cytogenetics but undetectable MRD overcomes the adverse prognosis. Interestingly, in patients with intermediate or high MRD levels, intensification with transplant improved the outcome as compared with chemotherapy, while the type of intensification therapy did not influenced the outcome of patients with low MRD levels. Multivariate analysis revealed age, MRD and cytogenetics as independent variables. Moreover, a scoring system, easy in clinical practice, was generated based on MRD level and cytogenetics.This work was supported in part by Spanish grants from Fondo de Investigación Sanitaria-ISCIII (FIS 00/0023-03, PI12/02321), DGCYT (SAF 94- 0308, SAF2001-1687), Conserjería de Educación de Castilla y León (HUS416A12), and Red Temática de Investigación Cooperativa en Cáncer (RTICC-ISCIII) (RD12/0036/0069).Peer Reviewe

Fluorescence Guided Surgery with 5-Aminolevulinic Acid for Resection of Spinal Cord Ependymomas

Study Design A retrospective study. Purpose We report our experience with 5-aminolevulinic acid (5-ALA)–assisted resection of spinal cord ependymomas in adults. Overview of Literature Ependymoma is the most frequent primary spinal cord tumor in adults. Surgery is the treatment of choice in most cases. However, while complete resection is achieved in approximately 80% of cases, clinical improvement is achieved in 15% only. Five-ALA fluorescence–guided surgery seems to be useful for this tumor type. Methods We studied 14 patients undergoing 5-ALA fluorescence-guided surgery for spinal cord ependymomas in our service. The modified McCormick classification was used to determine clinical status and the degree of resection was assessed with magnetic resonance imaging. Results Of the 14 patients, the tumor showed an intense emission of fluorescence in 12 and the fluorescence was weak and nonuniform in two. Complete resection was achieved in 11 cases. According to the McCormick classification, 10 patients improved, two remained the same, and two deteriorated. Conclusions Our results confirm that 5-ALA fluorescence-guided resection is useful in spinal cord ependymoma resection. Although the rate of complete resections is similar to that in published series without 5-ALA, clinical results are better when using 5-ALA with a lower percentage of clinical deterioration

Potential of Native Microalgae from the Peruvian Amazon on the Removal of Pollutants

Environmental pollution is a severe and common problem in all the countries worldwide. Various physicochemical technologies and organisms (e.g., plants, microorganisms, etc.) are used to address these environmental issues, but low-cost, practical, efficient, and effective approaches have not been available yet. Microalgae offer an attractive, novel, and little-explored bioremediation alternative because these photosynthetic organisms can eliminate pathogenic microorganisms and remove heavy metals and toxic organic compounds through processes still under study. Our research team has conducted some experiments to determine the bioremediation potential of native microalgae on some pollutant sources (i.e., leachate and wastewater) and its ability to remove hazardous chemical compounds. Therefore, in this chapter, we provide the results of our research and updated information about this exciting topic. Experiments were conducted under controlled culture conditions using several native microalgae species, variable time periods, different pollutant sources, and hazardous chemicals such as ethidium bromide. The results indicated that native microalgae can remove pollutants (i.e., phosphorus, ammonia, etc.) of wastewater, leachate, and some hazardous chemical compounds such as ethidium bromide. In conclusion, native microalgae have an excellent potential for removing several pollutants and, consequently, could be used to develop bioremediation technologies based on native microalgae from the Peruvian Amazon