ATP as a presynaptic modulator

© 2000 Elsevier Science Inc.There is considerable evidence that ATP acts as a fast transmitter or co-transmitter in autonomic and sensory nerves mostly through activation of ionotropic P2X receptors but also through metabotropic P2Y receptors. By analogy, the observations that ATP is released from stimulated central nervous system (CNS) nerve terminals and that responses to exogenously added ATP can be recorded in central neurons, lead to the proposal that ATP might also be a fast transmitter in the CNS. However, in spite of the robust expression of P2 receptor mRNA and binding to P2 receptors in the CNS, the demonstration of central purinergic transmission has mostly remained elusive. We now review evidence to suggest that ATP may also act presynaptically rather than solely postsynaptically in the nervous system.Fundação Ciência e Tecnologia and European nio

Deflationary cosmology: constraints from angular size and ages of globular clusters

Observational constraints to a large class of decaying vacuum cosmologies are derived using the angular size data of compact radio sources and the latest age estimates of globular clusters. For this class of deflationary $\Lambda(t)$ models, the present value of the vacuum energy density is quantified by a positive $\beta$ parameter smaller than unity. In the case of milliarcsecond compact radio-sources, we find that the allowed intervals for $\beta$ and the matter density parameter $\Omega_m$ are heavily dependent on the value of the mean projected linear size $l$. For $l \simeq 20h^{-1} - 30h^{-1}$ pc, the best fit occurs for $\beta \sim 0.58$, $\Omega_{\rm{m}} \sim 0.58$, and $\beta \sim 0.76$, $\Omega_{\rm{m}} \sim 0.28$, respectively. This analysis shows that if one minimizes $\chi^{2}$ for the free parameters $l$, $\Omega_{\rm{m}}$ and $\beta$, the best fit for these angular size data corresponds to a decaying $\Lambda(t)$ with $\Omega_{\rm{m}} = 0.54$ $\beta=0.6$ and $l = 22.64h^{-1}$ pc. Constraints from age estimates of globular clusters and old high redshift galaxies are not so restrictive, thereby suggesting that there is no age crisis for this kind of $\Lambda(t)$ cosmologies.Comment: 6 pages, 3 figures, revised version to appear in Phys. Rev.

Is Λ\LambdaCDM an effective CCDM cosmology?

We show that a cosmology driven by gravitationally induced particle production of all non-relativistic species existing in the present Universe mimics exactly the observed flat accelerating $\Lambda$CDM cosmology with just one dynamical free parameter. This kind of scenario includes the creation cold dark matter (CCDM) model [Lima, Jesus & Oliveira, JCAP 011(2010)027] as a particular case and also provides a natural reduction of the dark sector since the vacuum component is not needed to accelerate the Universe. The new cosmic scenario is equivalent to $\Lambda$CDM both at the background and perturbative levels and the associated creation process is also in agreement with the universality of the gravitational interaction and equivalence principle. Implicitly, it also suggests that the present day astronomical observations cannot be considered the ultimate proof of cosmic vacuum effects in the evolved Universe because $\Lambda$CDM may be only an effective cosmology.Comment: 6 pages, 2 figures, changes in the abstract, introduction, new references and typo correction

Accessing the Acceleration of the Universe with Sunyaev-Zel'dovich and X-ray Data from Galaxy Clusters

By using exclusively the Sunyaev-Zel'dovich effect and X-ray surface brightness data from 25 galaxy clusters in the redshift range 0.023< z < 0.784 we access cosmic acceleration employing a kinematic description. Such result is fully independent on the validity of any metric gravity theory, the possible matter-energy contents filling the Universe, as well as on the SNe Ia Hubble diagram.Comment: 3 pages, 4 figures, To appear in the Proceedings of the Twelfth Marcel Grossmann Meeting on General Relativit

Asteroseismology and Magnetic Cycles

Small cyclic variations in the frequencies of acoustic modes are expected to be a common phenomenon in solar-like pulsators, as a result of stellar magnetic activity cycles. The frequency variations observed throughout the solar and stellar cycles contain information about structural changes that take place inside the stars as well as about variations in magnetic field structure and intensity. The task of inferring and disentangling that information is, however, not a trivial one. In the sun and solar-like pulsators, the direct effect of the magnetic field on the oscillations might be significantly important in regions of strong magnetic field (such as solar- / stellar-spots), where the Lorentz force can be comparable to the gas-pressure gradient. Our aim is to determine the sun- / stellar-spots effect on the oscillation frequencies and attempt to understand if this effect contributes strongly to the frequency changes observed along the magnetic cycle. The total contribution of the spots to the frequency shifts results from a combination of direct and indirect effects of the magnetic field on the oscillations. In this first work we considered only the indirect effect associated with changes in the stratification within the starspot. Based on the solution of the wave equation and the variational principle we estimated the impact of these stratification changes on the oscillation frequencies of global modes in the sun and found that the induced frequency shifts are about two orders of magnitude smaller than the frequency shifts observed over the solar cycle.Comment: 4 pages, 6 figures, ESF Conference: The Modern Era of Helio- and Asteroseismology, to be published on 3 December 2012 at Astronomische Nachrichten 333, No. 10, 1032-103

Wang-Landau sampling in three-dimensional polymers

Monte Carlo simulations using Wang-Landau sampling are performed to study three-dimensional chains of homopolymers on a lattice. We confirm the accuracy of the method by calculating the thermodynamic properties of this system. Our results are in good agreement with those obtained using Metropolis importance sampling. This algorithm enables one to accurately simulate the usually hardly accessible low-temperature regions since it determines the density of states in a single simulation.Comment: 5 pages, 9 figures arch-ive/Brazilian Journal of Physic

Are Galaxy Clusters Suggesting an Accelerating Universe?

The present cosmic accelerating stage is discussed through a new kinematic method based on the Sunyaev- Zel'dovich effect (SZE) and X-ray surface brightness data from galaxy clusters. By using the SZE/X-ray data from 38 galaxy clusters in the redshift range $0.14 \leq z \leq 0.89$ [Bonamente et al., Astrop. J. {\bf 647}, 25 (2006)] it is found that the present Universe is accelerating and that the transition from an earlier decelerating to a late time accelerating regime is relatively recent. The ability of the ongoing Planck satellite mission to obtain tighter constraints on the expansion history through SZE/X-ray angular diameters is also discussed. Our results are fully independent on the validity of any metric gravity theory, the possible matter- energy contents filling the Universe, as well as on the SNe Ia Hubble diagram from which the presenting accelerating stage was inferred.Comment: 6 pages, 6 figures, AIP Conf. Proc. Invisible Universe: Proceedings of the Conferenc

Asteroseismic Theory of Rapidly Oscillating Ap Stars

This paper reviews some of the important advances made over the last decade concerning theory of roAp stars.Comment: 9 pages, 5 figure