Multi-View Collaborative Representation Classification

Department of Finance and Education of Guangdong Province 2016 [202]: Key Discipline Construction Program, China; Education Department of Guangdong Province: New and Integrated Energy System Theory and Technology Research Group [Project Number 2016KCXTD022]

Multi-seeded melt growth (MSMG) of bulk Y-Ba-Cu-O using thin-film seeds

Y-Ba-Cu-O (YBCO) and Sm-Ba-Cu-O (SmBCO) thin films have been used for the first time as heterogeneous seeds to multi-seed successfully the melt growth of bulk YBCO in a multi-seeded melt growth (MSMG) process. The use of thin film seeds, which may be prepared with highly controlled orientation (i.e. with a well-defined a-b plane and precisely known a-direction), is based on their superheating properties and reduces significantly contamination of the bulk sample by the seed material. A variety of grain boundaries were obtained by varying the angle between the seeds. Microstructural studies indicate that the extent of residual melt deposited at the grain boundary decreases with increasing grain boundary contact angle. It is established that the growth front proceeds continuously at the (110)/(110) grain boundary without trapping liquid, which leads to the formation of a clean grain boundary

A financial model for lithium-ion storage in a photovoltaic and biogas energy system

Electrical energy storage (EES) such as lithium-ion (Li-ion) batteries can reduce curtailment of renewables, maximizing renewable utilization by storing surplus electricity. Several techno-economic analyses have been performed on EES, but few have investigated the financial performance. This paper presents a state-of-the-art financial model obtaining novel and significative financial and economics results when applied to Li-ion EES. This work is a significant step forward since traditional analysis on EES are based on oversimplified and unrealistic economic models. A discounted cash flow model for the Li-ion EES is introduced and applied to examine the financial performance of three EES operating scenarios. Real-life solar irradiance, load, and retail electricity price data from Kenya are used to develop a set of case studies. The EES is coupled with photovoltaics and an anaerobic digestion biogas power plant. The results show the impact of capital cost: the Li-ion project is unprofitable in Kenya with a capital cost of 1500 $/kWh, but is profitable at 200$/kWh. The study shows that the EES will generate a higher profit if it is cycled more frequently (hence a higher lifetime electricity output) although the lifetime is reduced due to degradation

Multi-view deep forecasting for hourly solar irradiance with error correction

Short-term solar irradiance forecasting is crucial in managing power network operations and solar photovoltaic applications. In this paper, a Multi-view Deep Forecasting method with Error Correction (MvDF_EC) for 1-hour ahead solar forecasting is proposed. MvDF_EC comprises of the Multi-view Deep Forecasting method (MvDF) and a robust Radial Basis Function Neural Network trained via minimizing the Localized Generalization Error for compensating the solar forecasting error of MvDF. MvDF consists of three deep neural networks which learn representations of input data from different views. The three views are 1) the hierarchical local temporal information extracted by the Temporal Convolutional Neural Network (TCN), 2) the key context sequential information captured by the Bi-directional Long Short-Term Memory Neural Network with Temporal Attention (BLSTMattn), and 3) long-term temporal dependencies between local temporal patterns filtered by the Convolutional Gated Recurrent Unit Neural Network (C_GRU). The solar forecasting performance of the proposed MvDF_EC is evaluated with the National Solar Radiation Database. Simulation results show that MvDF_EC yields the most accurate solar prediction compared with the benchmarks including the smart persistence and the state-of-the-art models. The lowest relative Root Mean Square Error values for Maraba and Labelle are 22.08% and 27.40%, respectively in 1-hour ahead solar forecasting.National Natural Science Foundation of China under Grants 61876066 and 61572201; Guangzhou Science and Technology Plan Project 201804010245; Department of Finance and Education of Guangdong Province 2016 [202] Key Discipline Construction Program, China; the Education Department of Guangdong Province: New and Integrated Energy System Theory and Technology Research Group [Project Number 2016KCXTD022]; Brunel University London BRIEF Funding, UK

LHC Discovery Potential for Non-Standard Higgs Bosons in the 3b Channel

In a variety of well motivated models, such as two Higgs Doublet Models (2HDMs) and the Minimal Supersymmetric Standard Model (MSSM), there are neutral Higgs bosons that have significantly enhanced couplings to b-quarks and tau leptons in comparison to those of the SM Higgs. These so called non-standard Higgs bosons could be copiously produced at the LHC in association with b quarks, and subsequently decay into b-quark pairs. However, this production channel suffers from large irreducible QCD backgrounds. We propose a new search strategy for non-standard neutral Higgs bosons at the 7 TeV LHC in the 3b's final state topology. We perform a simulation of the signal and backgrounds, using state of the art tools and methods for different sets of selection cuts, and conclude that neutral Higgs bosons with couplings to b-quarks of about 0.3 or larger, and masses up to 400 GeV, could be seen with a luminosity of 30 fb^{-1}. In the case of the MSSM we also discuss the complementarity between the 3b channel and the inclusive tau pair channel in exploring the supersymmetric parameter space.Comment: 14 pages, 3 figures, 4 tables, references added, published versio

Primary extraskeletal osteosarcoma of omentum majus

Extraskeletal osteosarcoma is a rare malignant soft tissue tumor. Here we present a case of a primary extraskeletal osteosarcoma arising from omentum majus in a 40-year-old Chinese woman. Ultrasonography of the pelvic cavity showed a large soft tissue mass with marked calcification. Complete surgical resection of the primary tumor was performed and the histopathological diagnosis was extraskeletal osteosarcoma of omentum majus. She was followed up without adjuvant radiotherapy and chemotherapy, and died from widespread intra-abdominal, lung and liver metastases 7 months postoperatively

Revisit Neural Network based Load Forecasting

Department of Finance and Education of Guangdong Province 2016 [202]: Key Discipline Construction Program, China; Education Department of Guangdong Province: New and Integrated Energy System Theory and Technology Research Group [Project Number 2016KCXTD022]

An Analytical Model to Predict and Minimize the Residual Stress of Laser Cladding Process

Laser Cladding is one of the advanced thermal techniques used to repair or modify the surface properties of high value components such as tools, military and aerospace parts. Tensile residual stresses are formed in the thermally treated area of this process. This work focuses on to find out key factors of formation and minimization of tensile residual stresses in dissimilar materials. In order to predict the tensile residual stress, one dimensional analytical model has been adopted. Four cladding materials (Al2O3, TiC, TiO2, ZrO2) on the H13 tool steel substrate and a range of preheating temperature of the substrate, from 300K to 1200K, have been investigated. The thermal strain and Young’s modulus are found as key factors of formation and minimization of residual stresses. Additionally, the investigation of preheating temperature of the substrate showed the reduction of residual stress with increasing the preheating temperature of the substrate

Ribosomal oxygenases are structurally conserved from prokaryotes to humans

2-Oxoglutarate (2OG)-dependent oxygenases have important roles in the regulation of gene expression via demethylation of N-methylated chromatin components1,2 and in the hydroxylation of transcription factors3 and splicing factor proteins4. Recently, 2OG-dependent oxygenases that catalyse hydroxylation of transfer RNA5,6,7 and ribosomal proteins8 have been shown to be important in translation relating to cellular growth, TH17-cell differentiation and translational accuracy9,10,11,12. The finding that ribosomal oxygenases (ROXs) occur in organisms ranging from prokaryotes to humans8 raises questions as to their structural and evolutionary relationships. In Escherichia coli, YcfD catalyses arginine hydroxylation in the ribosomal protein L16; in humans, MYC-induced nuclear antigen (MINA53; also known as MINA) and nucleolar protein 66 (NO66) catalyse histidine hydroxylation in the ribosomal proteins RPL27A and RPL8, respectively. The functional assignments of ROXs open therapeutic possibilities via either ROX inhibition or targeting of differentially modified ribosomes. Despite differences in the residue and protein selectivities of prokaryotic and eukaryotic ROXs, comparison of the crystal structures of E. coli YcfD and Rhodothermus marinus YcfD with those of human MINA53 and NO66 reveals highly conserved folds and novel dimerization modes defining a new structural subfamily of 2OG-dependent oxygenases. ROX structures with and without their substrates support their functional assignments as hydroxylases but not demethylases, and reveal how the subfamily has evolved to catalyse the hydroxylation of different residue side chains of ribosomal proteins. Comparison of ROX crystal structures with those of other JmjC-domain-containing hydroxylases, including the hypoxia-inducible factor asparaginyl hydroxylase FIH and histone Nε-methyl lysine demethylases, identifies branch points in 2OG-dependent oxygenase evolution and distinguishes between JmjC-containing hydroxylases and demethylases catalysing modifications of translational and transcriptional machinery. The structures reveal that new protein hydroxylation activities can evolve by changing the coordination position from which the iron-bound substrate-oxidizing species reacts. This coordination flexibility has probably contributed to the evolution of the wide range of reactions catalysed by oxygenases

Agent based modelling helps in understanding the rules by which fibroblasts support keratinocyte colony formation

Background: Autologous keratincoytes are routinely expanded using irradiated mouse fibroblasts and bovine serum for clinical use. With growing concerns about the safety of these xenobiotic materials, it is desirable to culture keratinocytes in media without animal derived products. An improved understanding of epithelial/mesenchymal interactions could assist in this. Methodology/Principal Findings: A keratincyte/fibroblast o-culture model was developed by extending an agent-based keratinocyte colony formation model to include the response of keratinocytes to both fibroblasts and serum. The model was validated by comparison of the in virtuo and in vitro multicellular behaviour of keratinocytes and fibroblasts in single and co-culture in Greens medium. To test the robustness of the model, several properties of the fibroblasts were changed to investigate their influence on the multicellular morphogenesis of keratinocyes and fibroblasts. The model was then used to generate hypotheses to explore the interactions of both proliferative and growth arrested fibroblasts with keratinocytes. The key predictions arising from the model which were confirmed by in vitro experiments were that 1) the ratio of fibroblasts to keratinocytes would critically influence keratinocyte colony expansion, 2) this ratio needed to be optimum at the beginning of the co-culture, 3) proliferative fibroblasts would be more effective than irradiated cells in expanding keratinocytes and 4) in the presence of an adequate number of fibroblasts, keratinocyte expansion would be independent of serum. Conclusions: A closely associated computational and biological approach is a powerful tool for understanding complex biological systems such as the interactions between keratinocytes and fibroblasts. The key outcome of this study is the finding that the early addition of a critical ratio of proliferative fibroblasts can give rapid keratinocyte expansion without the use of irradiated mouse fibroblasts and bovine serum